The first outsider to run the company, Tobias is credited with orchestrating a major turnaround of Eli Lilly. Under his direction, Lilly introduced two successful drugs (Zyprexa for schizophrenia and Gemzar for cancer), solidified and expanded its blockbuster antidepressant drug, Prozac, and streamlined its overall operations. He managed costs and divested of non-core businesses, spinning off medical devices to form Guidant Corporation. Through his efforts, Lilly’s market capitalization grew from $14 billion to $70 billion.