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- June 2024
- Article
Enhancing Value and Well-Being: The Basket of Motivators Framework for Aligning Neurology Clinical Practices with Performance Outcomes
By: Peter N. Hadar, Susanna Gallani and Lidia Moura
Physician burnout, which is prevalent in neurology, has accelerated in recent years. While multifactorial, a major contributing factor to burnout is a payment model that rewards volume over quality, leaving physicians overburdened and unfulfilled. The aim of this...
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Keywords:
Compensation and Benefits;
Personal Development and Career;
Well-being;
Motivation and Incentives
Hadar, Peter N., Susanna Gallani, and Lidia Moura. "Enhancing Value and Well-Being: The Basket of Motivators Framework for Aligning Neurology Clinical Practices with Performance Outcomes." Neurology: Clinical Practice 14, no. 1 (June 2024).
- March 2024
- Case
From “BIG” Ideas to Sustainable Impact at ICL Group (A)
By: Linda A. Hill and Lydia Begag
In the summer of 2023, Eduard (“Eddie”) Croitoru, Vice President (VP) of ICL Group (“ICL”) Corporate Initiatives, was reflecting on ICL’s internal ideation program, the Business Innovation for Growth (BIG) Accelerator. When Raviv Zoller become the CEO of ICL in 2018,...
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Keywords:
Change Management;
Agribusiness;
Accounting;
Communication;
Engineering;
Energy;
Renewable Energy;
Chemicals;
Machinery and Machining;
Metals and Minerals;
Mining;
Social Entrepreneurship;
Corporate Entrepreneurship;
Values and Beliefs;
Environmental Sustainability;
Natural Resources;
Globalization;
Information Technology;
Innovation and Invention;
Leadership;
Organizational Culture;
Personal Development and Career;
Manufacturing Industry;
Agriculture and Agribusiness Industry;
Chemical Industry;
Israel;
China;
United States
- February 2024
- Case
ReSpo.Vision: The Kickstart of an AI Sports Revolution
By: Paul A. Gompers, Elena Corsi and Nikolina Jonsson
This case study explores the growth journey of Polish computer vision sports start-up ReSpo.Vision in an emerging entrepreneurial ecosystem. By providing 3D data and analysis to soccer clubs, ReSpo.Vision achieved significant milestones with a €1 million seed round, an...
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Keywords:
Business Startups;
Business Plan;
Experience and Expertise;
Talent and Talent Management;
Decisions;
Decision Choices and Conditions;
Forecasting and Prediction;
Entrepreneurship;
Venture Capital;
AI and Machine Learning;
Analytics and Data Science;
Applications and Software;
Sports Industry;
Technology Industry;
Poland;
Europe
- 2024
- Article
Beyond the 510(k): The Regulation of Novel Moderate-Risk Medical Devices, Intellectual Property Considerations, and Innovation Incentives in the FDA’s De Novo Pathway
By: Mateo Aboy, Cristina Crespo and Ariel Stern
Moderate-risk medical devices constitute 99% of those that have been regulated by the U.S. Food and Drug Administration (FDA) since it gained authority to regulate medical technology nearly five decades ago. This article presents an analysis of the interaction between...
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Keywords:
Governing Rules, Regulations, and Reforms;
Health Care and Treatment;
Technology Adoption;
Technological Innovation;
Safety;
Medical Devices and Supplies Industry;
United States
Aboy, Mateo, Cristina Crespo, and Ariel Stern. "Beyond the 510(k): The Regulation of Novel Moderate-Risk Medical Devices, Intellectual Property Considerations, and Innovation Incentives in the FDA’s De Novo Pathway." Art. 29. npj Digital Medicine 7 (2024).
- January 2024
- Technical Note
The ICARUS Principles: What It Takes to Tackle the World
By: Debora L. Spar and Julia M. Comeau
Over the course of the 20th century, most of the world’s major multinational corporations framed their mission around Milton Friedman’s famous mantra: that the sole purpose of the firm is to maximize its shareholders’ profits. Recently, however, growing numbers of...
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Keywords:
Purpose;
Mission;
Social Business;
Corporate Social Responsibility and Impact;
Mission and Purpose;
Social Enterprise
Spar, Debora L., and Julia M. Comeau. "The ICARUS Principles: What It Takes to Tackle the World." Harvard Business School Technical Note 324-055, January 2024.
- December 2023 (Revised February 2024)
- Case
Transforming Healthcare Delivery at Karolinska University Hospital
By: Susanna Gallani, Mary Witkowski, Elena Corsi and Nikolina Jonsson
The case study examines the journey toward value-based healthcare at Karolinska University Hospital. The hospital's ambitious shift to a patient-centered care delivery model, accompanied by the construction of a new facility, encountered challenges such as high costs,...
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Keywords:
Change Management;
Transformation;
Transition;
Business Organization;
Communication Strategy;
Information Infrastructure;
Service Delivery;
Organizational Change and Adaptation;
Organizational Structure;
Health Industry;
Sweden;
Europe
Gallani, Susanna, Mary Witkowski, Elena Corsi, and Nikolina Jonsson. "Transforming Healthcare Delivery at Karolinska University Hospital." Harvard Business School Case 124-070, December 2023. (Revised February 2024.)
- 2023
- Article
Benchmarking Large Language Models on CMExam—A Comprehensive Chinese Medical Exam Dataset
By: Junling Liu, Peilin Zhou, Yining Hua, Dading Chong, Zhongyu Tian, Andrew Liu, Helin Wang, Chenyu You, Zhenhua Guo, Lei Zhu and Michael Lingzhi Li
Recent advancements in large language models (LLMs) have transformed the field of question answering (QA). However, evaluating LLMs in the medical field is challenging due to the lack of standardized and comprehensive datasets. To address this gap, we introduce CMExam,...
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Keywords:
Large Language Model;
AI and Machine Learning;
Analytics and Data Science;
Health Industry
Liu, Junling, Peilin Zhou, Yining Hua, Dading Chong, Zhongyu Tian, Andrew Liu, Helin Wang, Chenyu You, Zhenhua Guo, Lei Zhu, and Michael Lingzhi Li. "Benchmarking Large Language Models on CMExam—A Comprehensive Chinese Medical Exam Dataset." Conference on Neural Information Processing Systems (NeurIPS), Datasets and Benchmarks Track 36 (2023).
- 2023
- Article
Dynamic HTA for Digital Health Solutions: Opportunities and Challenges for Patient-Centered Evaluation
By: Jan B. Brönneke, Annika Herr, Simon Reif and Ariel D. Stern
Germany’s 2019 Digital Healthcare Act (Digitale-Versorgung-Gesetz, or DVG) created a number of opportunities for the digital transformation of the health care delivery system. Key among these was the creation of a reimbursement pathway for patient-centered digital...
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Keywords:
Digital Transformation;
Applications and Software;
Product Development;
Insurance;
Policy;
Health Industry;
Germany
Brönneke, Jan B., Annika Herr, Simon Reif, and Ariel D. Stern. "Dynamic HTA for Digital Health Solutions: Opportunities and Challenges for Patient-Centered Evaluation." International Journal of Technology Assessment in Health Care 39, no. 1 (2023).
- 2023
- Article
Digital Health Reimbursement Strategies of 8 European Countries and Israel: Scoping Review and Policy Mapping
By: Robin van Kessel, Divya Srivastava, Ilias Kyriopoulos, Giovanni Monti, David Novillo-Ortiz, Ran Milman, Wojciech Wilhelm Zhang-Czabanowski, Greta Nasi, Ariel Dora Stern, George Wharton and Elias Mossialos
Background: The adoption of digital health care within health systems is determined by various factors, including pricing and reimbursement. The reimbursement landscape for digital health in Europe remains underresearched. Although various emergency reimbursement...
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Keywords:
Technology Adoption;
Health Care and Treatment;
Cross-Cultural and Cross-Border Issues;
Price;
Health Industry;
Europe;
Israel
van Kessel, Robin, Divya Srivastava, Ilias Kyriopoulos, Giovanni Monti, David Novillo-Ortiz, Ran Milman, Wojciech Wilhelm Zhang-Czabanowski, Greta Nasi, Ariel Dora Stern, George Wharton, and Elias Mossialos. "Digital Health Reimbursement Strategies of 8 European Countries and Israel: Scoping Review and Policy Mapping." e49003. JMIR mHealth and uHealth 11 (2023).
- 2023
- Working Paper
LALIGA—From a Soccer Competition Organizer to a Global Player in the Sports and Entertainment Industry
By: Stephen A. Greyser, Kenneth Cortsen and Juan Fuentes Fernández
LALIGA, the first- and second-tier professional soccer league (known as “football” outside of the U.S. and Canada) in Spain, enters its 100th soccer season later this decade. The most popular game in the world (Giulianotti, 2012) has gone through many changes since...
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Keywords:
Soccer;
"Sports Organizations,;
Business History;
Strategy;
Brands and Branding;
Technology Adoption;
Sports Industry
Greyser, Stephen A., Kenneth Cortsen, and Juan Fuentes Fernández. "LALIGA—From a Soccer Competition Organizer to a Global Player in the Sports and Entertainment Industry." Harvard Business School Working Paper, No. 24-009, August 2023.
- August 2023
- Case
Sky Therapeutics: Innovating in Digital Therapeutics
By: Satish Tadikonda and Olivia Reszczynski
Shad Faraz and Alex Youssef were intrigued by the opportunities in the relatively new area of Digital Therapeutics. Despite initial successes, early entrants had struggled with reimbursement and revenue-predictability challenges. However, venture investors still...
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Keywords:
Business Startups;
Entrepreneurship;
Mission and Purpose;
Health Industry;
Health Industry
Tadikonda, Satish, and Olivia Reszczynski. "Sky Therapeutics: Innovating in Digital Therapeutics." Harvard Business School Case 824-023, August 2023.
- June 2023
- Case
Biogen and the Aduhelm Melee
By: Amitabh Chandra and Lauren Gunasti
Alzheimer's Disease is a devastating condition affecting millions of Americans. At this time, there is no cure. In 2021, Biogen's Aduhelm (aducanumab) received FDA approval under the accelerated approval pathway after a controversial approval process.
This... View Details
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- June 2020
- Article
Real-time Data from Mobile Platforms to Evaluate Sustainable Transportation Infrastructure
By: Omar Isaac Asensio, Kevin Alvarez, Arielle Dror, Emerson Wenzel, Catharina Hollauer and Sooji Ha
By displacing gasoline and diesel fuels, electric cars and fleets reduce emissions from the transportation sector, thus offering important public health benefits. However, public confidence in the reliability of charging infrastructure remains a fundamental barrier to...
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Keywords:
Environmental Sustainability;
Transportation;
Infrastructure;
Behavior;
AI and Machine Learning;
Demand and Consumers
Asensio, Omar Isaac, Kevin Alvarez, Arielle Dror, Emerson Wenzel, Catharina Hollauer, and Sooji Ha. "Real-time Data from Mobile Platforms to Evaluate Sustainable Transportation Infrastructure." Nature Sustainability 3, no. 6 (June 2020): 463–471.
- May 2023 (Revised June 2023)
- Case
Novartis (A): Reimagining Medicine
By: Ramon Casadesus-Masanell, Claudio Feser, Karolin Frankenberger and David Redaschi
This case unfolds around the first-ever approved personalized cancer treatment, how Novartis wrapped it into a new business model design, and how Novartis scaled it. Novartis — one of the largest pharmaceutical companies in the world — is, among other ventures,...
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Keywords:
Health Care and Treatment;
Business Model;
Leadership;
Pharmaceutical Industry;
Switzerland
Casadesus-Masanell, Ramon, Claudio Feser, Karolin Frankenberger, and David Redaschi. "Novartis (A): Reimagining Medicine." Harvard Business School Case 723-443, May 2023. (Revised June 2023.)
- May 2023 (Revised June 2023)
- Supplement
Novartis (B): Reimagining Medicine
By: Ramon Casadesus-Masanell, Claudio Feser, Karolin Frankenberger and David Redaschi
This case unfolds around the first-ever approved personalized cancer treatment, how Novartis wrapped it into a new business model design, and how Novartis scaled it. Novartis — one of the largest pharmaceutical companies in the world — is, among other ventures,...
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Keywords:
Health Care and Treatment;
Business Model;
Production;
Business Strategy;
Pharmaceutical Industry
Casadesus-Masanell, Ramon, Claudio Feser, Karolin Frankenberger, and David Redaschi. "Novartis (B): Reimagining Medicine." Harvard Business School Supplement 723-444, May 2023. (Revised June 2023.)
- May 2023 (Revised June 2023)
- Supplement
Novartis (C): Reimagining Medicine
By: Ramon Casadesus-Masanell, Claudio Feser, Karolin Frankenberger and David Redaschi
This case unfolds around the first-ever approved personalized cancer treatment, how Novartis wrapped it into a new business model design, and how Novartis scaled it. Novartis — one of the largest pharmaceutical companies in the world — is, among other ventures,...
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Keywords:
Health Testing and Trials;
Health Care and Treatment;
Business Model;
Problems and Challenges;
Pharmaceutical Industry;
Switzerland
Casadesus-Masanell, Ramon, Claudio Feser, Karolin Frankenberger, and David Redaschi. "Novartis (C): Reimagining Medicine." Harvard Business School Supplement 723-445, May 2023. (Revised June 2023.)
- April 2023 (Revised September 2023)
- Case
Levels: The Remote, Asynchronous, Deep Work Management System
By: Joseph B. Fuller and George Gonzalez
Levels is a highly innovative startup in the health care space. They intend to revolutionize health by linking behavior—eating, exercise, sleeping, etc.—to changes in metabolism. They believe metabolic health can be managed through careful monitoring of changes in...
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Keywords:
Applications and Software;
Business Startups;
Organizational Culture;
Management Style;
Technology Industry;
United States
Fuller, Joseph B., and George Gonzalez. "Levels: The Remote, Asynchronous, Deep Work Management System." Harvard Business School Case 323-069, April 2023. (Revised September 2023.)
- March 2023
- Case
Between Two Minds: The Staglin Family
By: Lauren Cohen, Ronnie Stangler and Grace Headinger
Garen Staglin, Founder and Chairman of One Mind, reflected on his life’s work in brain health. As he contemplated stepping down in the next few years, he weighed how to pass along this legacy to his son, Brandon Staglin, the impetus behind and next generation of the...
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Keywords:
Nonprofit Organizations;
Well-being;
Management Succession;
Family Ownership;
Mission and Purpose;
Health Industry
Cohen, Lauren, Ronnie Stangler, and Grace Headinger. "Between Two Minds: The Staglin Family." Harvard Business School Case 223-053, March 2023.
- March 2023
- Case
Moderna
By: Marco Iansiti, Karim R. Lakhani, Hannah Mayer, Kerry Herman, Allison J. Wigen and Dave Habeeb
This multimedia case follows the story of Moderna and its entry into vaccine development in the wake of the COVID-19 pandemic. In summer 2020, Stephane Bancel, CEO of biotech firm Moderna, faces several challenges as his company races to develop a vaccine for COVID-19....
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- March 2023
- Case
Innovation at Google Ads: The Sales Acceleration and Innovation Labs (SAIL) (A)
By: Linda A. Hill and Emily Tedards
In 2018, Ana Owczarzak was appointed to lead Google Ads' new innovation and accelerator team - the Sales Acceleration and Innovation Labs (SAIL). The purpose of SAIL was to offer testing and incubation services for individuals within Google Ads who were developing new...
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Keywords:
Innovation Leadership;
Innovation Strategy;
Organizational Design;
Technology Industry;
Advertising Industry;
Information Technology Industry;
United States
Hill, Linda A., and Emily Tedards. "Innovation at Google Ads: The Sales Acceleration and Innovation Labs (SAIL) (A)." Harvard Business School Case 423-076, March 2023.