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May 2025
Background Note

Social Enterprise in Latin America

By: Brian L. Trelstad and Karina Souza

This research note provides an overview of the social enterprise ecosystem in Latin America, exploring current dynamics across key markets, including country-specific insights on Brazil, Mexico, Argentina, Colombia, Chile, and Central America. In a region characterized... View Details

May 2025
Case

'Net Zero in Action': Impact Investing at the McKnight Foundation

By: Lauren Cohen, Christina R. Wing and Sophia Pan

Elizabeth McGeveran, Vice President of Investments at the McKnight Foundation, reflected on how to effectively advance the organization’s net-zero strategy. The foundation had committed 10% of its endowment to building a portfolio of impact investments and was among... View Details

April 2025
Case

The CHIPS Program Office (Abridged)

By: Mitch Weiss and Sebastian Negron-Reichard

In February 2023, U.S. Commerce Secretary Gina Raimondo weighed signing off on a Notice of Funding Opportunity (“NOFO”) with at least one unconventional provision: a pre-application (“pre-app”) to the actual application for parts of $39 billion in direct semiconductor... View Details

Keywords: Entrepreneurship; Public Sector; Government Administration; Government Legislation; Motivation and Incentives; Semiconductor Industry; Public Administration Industry; United States

2025
Book

The Experimentation Machine: Finding Product–Market Fit in the Age of AI

By: Jeffrey J. Bussgang

Leverage AI to be a 10x Founder

Today’s most successful founders know that the startups that learn the fastest will win. In The Experimentation Machine, I reveal how AI is transforming the way startups find product-market fit and scale.... View Details

Keywords: AI; Founder; Startup; AI and Machine Learning; Technology Adoption; Business Startups; Entrepreneurship; Market Entry and Exit

March 2025
Case

Mobvoi's Path Through Market Challenges and Business Reinvention

By: Paul A. Gompers and Shu Lin

Founded in 2012, Mobvoi evolved through multiple transformations—from AI-driven voice technology to smart wearables and later AI-generated content. Backed by major investors, the company navigated shifts in strategy while facing two failed IPO attempts. As market... View Details

Keywords: Business Startups; Entrepreneurship; AI and Machine Learning; Transformation; Initial Public Offering; Business Strategy; Technology Industry; China

March 2025
Case

Niramai: An AI Solution to Save Lives

By: Rembrand Koning, Maria P. Roche and Kairavi Dey

Founded in 2017, Niramai developed Thermalytix, a breast cancer screening tool. Thermalytix used a high-resolution thermal sensing device and machine learning algorithms to analyze thermal images and detect tumors. Its patented solution leveraged big data analytics,... View Details

Keywords: Entrepreneurship; AI and Machine Learning; Technology Adoption; Health Care and Treatment; Technology Industry; Technology Industry; Asia; India; South Asia

February 2025
Supplement

Intenseye: Powering Workplace Health and Safety with AI (B)

By: Michael W. Toffel, Shane Greenstein and Sadika El Hariri

Intenseye used its $25 million series A funds to refine and expand its digital safety platform while refining its target markets and ideal customer profile. As the company implemented new approaches to create value for its clients, such as developing an AI-powered... View Details

February 2025
Case

Doing Business in Casablanca, Morocco

By: Karen G. Mills, Ahmed Dahawy and Choetsow Tenzin

This case examines the challenges and opportunities of doing business in Morocco. The case explores the various historical, cultural, and social factors that impact the business environment. It also highlights Morocco’s unique economy where cash remains a dominant... View Details

Keywords: Business Model; Cultural Entrepreneurship; Social Entrepreneurship; Business History; Business and Government Relations; Technological Innovation; Cash; Culture; Distribution Industry; Financial Services Industry; Morocco

February 2025
Case

Fly, Fix, Fly at True Anomaly

By: Joshua Lev Krieger, Jim Matheson, Fiona Murray and David Allen

How should companies learn from failure? Founded by four U.S. Space Force warfighters, the tough tech startup True Anomaly wanted to compete with major defense contractors to supply the U.S. Department of Defense with satellites and software that could help protect... View Details

Keywords: Business Startups; Engineering; National Security; Digital Platforms; Failure; Problems and Challenges; Business and Government Relations; Entrepreneurship; Aerospace Industry; United States; Colorado

January 2025
Case

Summer Health: Raising an AI-First Company?

By: Jeffrey J. Bussgang, Sarah Mehta and Maxim Pike Harrell

In October 2023, Summer Health CEO Ellen DaSilva arrived at a defining juncture for her pediatric telehealth startup. Founded in 2021, Summer Health offered parents rapid access to licensed pediatricians via text message. DaSilva, an experienced telehealth executive,... View Details

Keywords: AI and Machine Learning; Technology Adoption; Entrepreneurship; Leadership; Business Startups; Health Care and Treatment; Business Strategy; Product Development; Health Industry; Telecommunications Industry; United States

January 2025
Case

Untapped Global: Financing Africa's Missing Middle

By: Raymond Kluender and Emanuele Colonnelli

In November 2024, Jim Chu, founder and CEO of Untapped Global, faced mounting internal tensions over the company’s strategic direction. Untapped had developed a data-driven revenue-based financing (RBF) model to address the “missing middle” problem—the $5.2 trillion... View Details

January 2025
Case

PayJoy: Financing for the Next Billion

By: Boris Groysberg and Sarah L. Abbott

PayJoy, an impact-driven financial technology company founded in 2015, provides smartphone financing and other financial products to customers who lack access to traditional credit products. As of early 2025, PayJoy had issued $2.5 billion in loans to 13 million... View Details

January 2025
Teaching Note

Vytal: Packaging-as-a-Service

By: George Serafeim, Michael W. Toffel and Stacy Straaberg

Teaching Note for HBS Case No. 124-007. The Germany-based startup Vytal operated the largest digital-native reusable packaging-as-a-service network globally, having raised nearly €15 million, established a large network of restaurant partners, and prevented the use of... View Details

January 2025 (Revised April 2025)
Case

Blue Frontier: Disrupting Air Conditioning

By: Rosabeth Moss Kanter and Jacob A. Small

Serial entrepreneur Daniel Betts founded Blue Frontier in South Florida to offer a climate-friendly solution to increase air conditioning efficiency and dehumidify using new technology he developed. Backed by significant venture capital, Blue Frontier had to choose... View Details

Keywords: Entrepreneurship; Climate Change; Environmental Sustainability; Technological Innovation; Market Entry and Exit; Performance Efficiency; Business Strategy; Florida

January 2025 (Revised April 2025)
Case

Mercado Libre: The Best Is Yet to Come

By: Krishna G. Palepu, Fernando Fragueiro, Carla Larangeira and Mariana Cal

In 2024, Marcos Galperín, CEO and co-founder of Mercado Libre, reflected on its 25-year rise as Latin America’s largest marketplace, fintech leader, and most valuable public company. With operations spanning 18 countries and a robust ecosystem combining e-commerce,... View Details

December 2024
Case

Core Innovation Capital: Investing in Fintech for Good

By: Ray Kluender, Natalia Rigol, Benjamin Roth and Nicole Tempest Keller

In 2017, Arjan Schütte, founder of Core Innovation Capital, faced a decision on whether to invest in Hugo Insurance, an auto insurance startup. Core, an early-stage social impact VC firm, focused on “fintech for good,” by investing in financial services for low- to... View Details

Keywords: Fintech; Venture Capital; Social Entrepreneurship; Insurance; Measurement and Metrics; Investment; Corporate Social Responsibility and Impact; Product Positioning; Technology Industry; Technology Industry; Technology Industry; United States

December 2024
Supplement

Core Innovation Capital: Investing in Fintech for Good (B)

By: Ray Kluender, Natalia Rigol, Benjamin Roth and Nicole Tempest Keller

In 2017, Core Innovation Capital invested $725,000 in Hugo Insurance, a pay-as-you-drive auto insurance startup targeting the non-standard market. Core followed with $300,000 in 2019 during a Seed II round. By 2022, Hugo founder, David Bergendahl, sought $10 million in... View Details

Keywords: Fintech; Venture Capital; Social Entrepreneurship; Insurance; Measurement and Metrics; Investment; Technology Industry; Technology Industry; Technology Industry; United States

10 Dec 2024
Interview

A New Model for Funding Healthcare Innovation

By: Regina E. Herzlinger and Duke Rohlen

Ajax Health founder Duke Rohlen (HBS MBA 2001) and HBS Professor Regina Herzlinger join host Brian Kenny to discuss the key success factors for both start-up and established medical technology firms. The case “Ajax Health: A New Model for Medical Technology Innovation”... View Details

Keywords: Entrepreneurship; Innovation and Invention; Business Model; Private Equity; Health Industry

December 2024
Case

Xtalic

By: Joshua Lev Krieger and Jim Matheson

This case study examines the commercialization efforts of Xtalic, a startup founded by MIT scientists based on their discovery of a novel material science method to protect metal substrates. The case focuses on the strategic decisions involved in bringing this... View Details

Keywords: Innovation ＆ Entrepreneurship; Innovation and Management; Entrepreneurial Finance; Entrepreneurship; Business Model; Business Startups; Agreements and Arrangements; Science-Based Business; Commercialization

2024
Working Paper

Charting (and Updating) the Path: A Bayesian Perspective on Entrepreneurial Learning

By: Joshua L. Krieger

This chapter explores two distinct modes of entrepreneurial learning: assessing venture viability and choosing between alternative development paths. It introduces a framework for decomposing venture viability into technological feasibility, commercial potential and... View Details

Keywords: Decision Making; Entrepreneurship; Growth and Development Strategy; Learning

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