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Publications

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      • January 2023
      • Case

      Cleave Therapeutics: Taking a Risk on Oncology Drug Discovery

      By: Regina Herzlinger and Brian Walker
      How can a successful executive assess her next move as the CEO of a firm with a promising and yet uncertain new drug? Amy Burroughs’ mandate to find a therapeutic window for Cleave Therapeutics oncology drug was on track but faced an uncertain future. Overseeing the...  View Details
      Keywords: Product Development; Leadership; Health Testing and Trials; Research and Development; Risk and Uncertainty; Financial Condition; Partners and Partnerships; Pharmaceutical Industry
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      Herzlinger, Regina, and Brian Walker. "Cleave Therapeutics: Taking a Risk on Oncology Drug Discovery." Harvard Business School Case 323-045, January 2023.
      • January 2023
      • Case

      Nick Saban: Embracing “The Process” of Sustaining Success

      By: Ranjay Gulati and Eppa Rixey
      Nick Saban, head coach of the University of Alabama football team from 2007-2022, fielded teams that won 183 of 208 games (88%), including a record-tying six national championships. Saban’s approach to coaching, known to many as “The Process,” and the consistent...  View Details
      Keywords: Purpose; Leadership And Managing People; Football; Recruiting; Talent Acquisition; Talent And Talent Management; Talent Development And Retention; Organization Change And Adaptation; Organizational Behavior; Sports; Leadership; Leadership Development; Organizational Culture; Organizational Change and Adaptation; Sports Industry; United States
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      Gulati, Ranjay, and Eppa Rixey. "Nick Saban: Embracing “The Process” of Sustaining Success." Harvard Business School Case 423-033, January 2023.
      • January–February 2023
      • Article

      The Overlooked Key to a Successful Scale-Up

      By: Jeffrey F. Rayport, Davide Sola and Martin Kupp
      Many start-ups experience enormous popularity and runaway growth, but only a few go on to become stable giants. What separates them from the pack? They all go through a developmental stage called extrapolation, say three business school professors.
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      Keywords: Entrepreneurship And Strategy; Scalability; Business Startups; Growth and Development Strategy; Entrepreneurship
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      Rayport, Jeffrey F., Davide Sola, and Martin Kupp. "The Overlooked Key to a Successful Scale-Up." Harvard Business Review (January–February 2023): 56–65.
      • 2022
      • Working Paper

      Nailing Prediction: Experimental Evidence on the Value of Tools in Predictive Model Development

      By: Daniel Yue, Paul Hamilton and Iavor Bojinov
      Predictive model development is understudied despite its importance to modern businesses. Although prior discussions highlight advances in methods (along the dimensions of data, computing power, and algorithms) as the primary driver of model quality, the value of tools...  View Details
      Keywords: Analytics and Data Science
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      Yue, Daniel, Paul Hamilton, and Iavor Bojinov. "Nailing Prediction: Experimental Evidence on the Value of Tools in Predictive Model Development." Harvard Business School Working Paper, No. 23-029, December 2022.
      • December 2022
      • Case

      Iberdrola: Leading the Energy Revolution

      By: Juan Alcácer and Emer Moloney
      At the end of 2019, Ignacio Galán, the Chairman and CEO of the world's third largest utility, Iberdrola, relected on his almost 20 years at the company. He managed a portfolio of three very different businesses, each with their own specific opportunities and...  View Details
      Keywords: Energy; Energy Generation; Energy Sources; Non-Renewable Energy; Renewable Energy; Engineering; Innovation and Management; Innovation Leadership; Innovation Strategy; Technological Innovation; Leadership; Growth and Development Strategy; Market Timing; Industry Growth; Mission and Purpose; Strategy; Energy Industry; Green Technology Industry; Utilities Industry; Transportation Industry; Auto Industry; Spain; United Kingdom; United States; Brazil; Mexico
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      Alcácer, Juan, and Emer Moloney. "Iberdrola: Leading the Energy Revolution." Harvard Business School Case 723-398, December 2022.
      • November 2022 (Revised December 2022)
      • Case

      Replika AI: Monetizing a Chatbot

      By: Julian De Freitas and Nicole Tempest Keller
      In early 2018, Eugenia Kuyda, co-founder and CEO of San Francisco-based chatbot Replika AI, was deciding how to monetize the app she had built. Launched in 2017, Replika was a consumer AI “companion app” developed by a team of AI software engineers originally based in...  View Details
      Keywords: Mental Health; Subscriber Models; TAM; Monetization Strategy; Marketing Strategy; Product Marketing; AI and Machine Learning; Applications and Software; Product Positioning; Health Disorders; Technology Industry
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      De Freitas, Julian, and Nicole Tempest Keller. "Replika AI: Monetizing a Chatbot." Harvard Business School Case 523-016, November 2022. (Revised December 2022.)
      • November 2022
      • Case

      Goonj: Growing in the Face of a Pandemic

      By: V. Kasturi Rangan and Priyank Narayan
      Founded by the husband and wife team of Anshu and Meenakshi Gupta in 1999, Goonj had quickly emerged as one of the leading disaster relief and rural development organizations in India. Their main mode of development was through providing a clothing kit to the village...  View Details
      Keywords: COVID-19 Pandemic; Management; Family Business; Natural Disasters; Social Issues; Entrepreneurship; Operations; Business and Community Relations; Strategy; India
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      Rangan, V. Kasturi, and Priyank Narayan. "Goonj: Growing in the Face of a Pandemic." Harvard Business School Case 523-051, November 2022.
      • November 2022
      • Teaching Note

      Proximie: Using XR Technology to Create Borderless Operating Rooms

      By: Ariel D. Stern, Alpana Thapar and Menna Hassan
      Founded by Nadine Hachach-Haram in 2016, Proximie was a digital medicine platform that used mixed reality and a host of digital audio and visual tools to enable clinicians, proctors, and medical device company personnel to be virtually present in operating rooms (ORs),...  View Details
      Keywords: Technological Innovation; Business Growth and Maturation; Growth and Development Strategy; Corporate Social Responsibility and Impact; Decision Making; Health Industry; Medical Devices and Supplies Industry
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      Stern, Ariel D., Alpana Thapar, and Menna Hassan. "Proximie: Using XR Technology to Create Borderless Operating Rooms." Harvard Business School Teaching Note 623-034, November 2022.
      • November 2022 (Revised December 2022)
      • Case

      Ava Labs: Navigating the Next Blockchain

      By: Marco Di Maggio and Wenyao Sha
      John Wu, President of Ava Labs, the primary developer of the Avalanche blockchain, and Emin Gün Sirer, the software company’s Founder and CEO, team up to develop a lending and borrowing protocol that would jumpstart the Decentralized finance (DeFi) economy on...  View Details
      Keywords: Blockchain; Decentralized Finance; Alternative Assets; Financial Instruments; Assets; Decisions; Financing and Loans; Technology Industry; Financial Services Industry
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      Di Maggio, Marco, and Wenyao Sha. "Ava Labs: Navigating the Next Blockchain." Harvard Business School Case 223-027, November 2022. (Revised December 2022.)
      • November 2022
      • Case

      The Globalization of Manchester City Football Group

      By: Maria P. Roche, Tiona Zuzul, Exequiel Hernandez and Amy Klopfenstein
      This case describes the efforts of City Football Group (CFG) to purchase Esporte Clube Bahia (Bahia), a Brazilian professional soccer club. CFG’s strategy was to acquire under-performing clubs worldwide, invest money in high-profile players, and improve the teams’...  View Details
      Keywords: Business Ventures; Acquisition; Business Conglomerates; Geography; Geographic Location; Geographic Scope; Globalization; Global Strategy; Globalized Markets and Industries; Markets; Demand and Consumers; Marketing; Brands and Branding; Organizations; Organizational Change and Adaptation; Sports; Strategy; Competition; Competitive Advantage; Diversification; Expansion; Sports Industry; Europe; United Kingdom; England; South America; Brazil
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      Roche, Maria P., Tiona Zuzul, Exequiel Hernandez, and Amy Klopfenstein. "The Globalization of Manchester City Football Group." Harvard Business School Case 723-391, November 2022.
      • November 2022
      • Case

      Arcos Dorados’ Quest for the Digitalization of Last-Mile Delivery in Colombia

      By: Jorge Tamayo, Jenyfeer Martinez Buitrago and Mariana Cal
      In 2018, Francisco Staton, Managing Director of Arcos Dorados in Colombia had to decide on the company’s strategy to expand its food ordering and delivery business in the country. Arcos Dorados stood as McDonald’s largest independent franchisee, and Colombia was one of...  View Details
      Keywords: Digital Transformation; Delivery; McDonald's; Latin America; Quick Serve Restaurants; QSR; Transformation; Decision Making; Decision Choices and Conditions; Global Strategy; Technological Innovation; Growth and Development Strategy; Agreements and Arrangements; Negotiation Tactics; Logistics; Service Delivery; Organizational Culture; Performance Improvement; Partners and Partnerships; Strategy; Food and Beverage Industry; Latin America; South America; Colombia
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      Tamayo, Jorge, Jenyfeer Martinez Buitrago, and Mariana Cal. "Arcos Dorados’ Quest for the Digitalization of Last-Mile Delivery in Colombia." Harvard Business School Case 723-395, November 2022.
      • October 2022
      • Case

      Podimetrics: Next Steps for Diabetes Cases

      By: Regina E. Herzlinger and Ben Creo
      Podimetrics, a virtual care management company treating adults with acute diabetes, sat at the intersection of medical device technology, data, and health services. Their leadership team considered the best next step for the company to take—would it be expanding the...  View Details
      Keywords: Health Care; Health Care Delivery; Health Care Entrepreneurship; Health Care Outcomes; Diabetes; Chronic Disease; Chronic Illness; Health Care and Treatment; Health Disorders; Medical Specialties; Technological Innovation; Innovation Strategy; Product Development; Business Model; Customer Focus and Relationships; Medical Devices and Supplies Industry; Health Industry
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      Herzlinger, Regina E., and Ben Creo. "Podimetrics: Next Steps for Diabetes Cases." Harvard Business School Case 323-015, October 2022.
      • September 2022
      • Case

      HPP: Tapping the Netherlands’ Potential

      By: Brian Trelstad and Idelès Kaandorp
      Stichting Het Potentieel Pakken (HPP) was launched to solve a systemic problem in the Dutch Labor Market: gender inequity that was leading to a large number of women to work part-time in fields that were in desperately short supply of labor, like health care, child...  View Details
      Keywords: COVID-19 Pandemic; Grants; Scaling And Growth; Nonprofit Organizations; Opportunities; Gender; Income; Employment; Health Care and Treatment; Human Capital; Mission and Purpose; Motivation and Incentives; Growth and Development Strategy; Employment Industry; Health Industry; Education Industry; Consulting Industry; Europe; Netherlands
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      Trelstad, Brian, and Idelès Kaandorp. "HPP: Tapping the Netherlands’ Potential." Harvard Business School Case 323-024, September 2022.
      • August 2022
      • Case

      Southwick Social Ventures

      By: Henry McGee, Mel Martin and Amy Klopfenstein
      In 2021, the HBS Impact Investment Fund student team had found a promising potential investment in Southwick Social Ventures (SSV), a worker and management-owned trouser manufacturer. With a 100% immigrant workforce, the co-operative was focused on reviving...  View Details
      Keywords: Impact Investing; Entrepreneurship; Social Entrepreneurship; Finance; Investment; Goods and Commodities; Manufacturing Industry; United States; Massachusetts
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      McGee, Henry, Mel Martin, and Amy Klopfenstein. "Southwick Social Ventures." Harvard Business School Case 323-011, August 2022.
      • August 2022
      • Case

      In-Q-Tel: Innovation On A Mission

      By: Joshua Lev Krieger and Josh Lerner
      In 2022, the leaders of In-Q-Tel (IQT) considered what was next for the unique mission-driven organization. Since 1999, IQT had one mission: to be the most sophisticated source of strategic technical knowledge and capabilities to the U.S. government and its allies. IQT...  View Details
      Keywords: Mission and Purpose; National Security; Technological Innovation; Research; Geopolitical Units; Risk Management; Recruitment; Growth and Development Strategy; Venture Capital; Knowledge Management; Information Industry; Banking Industry
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      Krieger, Joshua Lev, and Josh Lerner. "In-Q-Tel: Innovation On A Mission." Harvard Business School Case 823-031, August 2022.
      • August 2022
      • Case

      Rocket Learning: Evidence in Action

      By: Brian Trelstad, Tomas Rosales and Malini Sen
      Founders of Rocket Learning, an India-based nonprofit which focused on early childhood education (ECE), received an invitation from MIT’s Abdul Latif Jameel Poverty Action Lab (JPAL), a development research organization, to test its intervention for ECE with a...  View Details
      Keywords: Social Entrepreneurship; Early Childhood Education; Nonprofit Organizations; Literacy; Values and Beliefs; Social and Collaborative Networks; Education Industry; India; Asia
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      Trelstad, Brian, Tomas Rosales, and Malini Sen. "Rocket Learning: Evidence in Action." Harvard Business School Case 323-002, August 2022.
      • July 2022
      • Case

      Operation Overlord

      By: Boris Groysberg, Greg Goullet, Katherine Connolly Baden and Sarah L. Abbott
      On June 6, 1944, nearly 5,000 ships, 11,000 planes, and 160,000 infantrymen under an Allied joint-command of American, British, and Canadian leaders were sent across the English Channel, with hopes of re-establishing a foothold in Nazi-occupied France. Known as D-Day,...  View Details
      Keywords: Execution; Data Analytics; Leadership; Planning; Operations; Crisis Management; War; Organizational Structure; Decision Choices and Conditions; Information Management; France; England
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      Groysberg, Boris, Greg Goullet, Katherine Connolly Baden, and Sarah L. Abbott. "Operation Overlord." Harvard Business School Case 422-098, July 2022.
      • July 2022
      • Teaching Note

      The DivaCup: Navigating Distribution and Growth

      By: Ayelet Israeli
      Teaching Note for HBS Case No. 519-055. When the mother-daughter founders of DivaCup set out with a mission to disrupt the menstrual care industry with an innovative product form, they initially struggled to gain legitimacy and convince retailers to carry their unique...  View Details
      Keywords: Female; Female Ceo; Female Entrepreneur; Female Protagonist; Health & Wellness; Healthcare; Price Policies; Minimum Advertised Price; Differentiation; Positioning; Growth; Health; Health Care and Treatment; Price; Disruption; Distribution; Distribution Channels; Competitive Strategy; Competition; Growth Management; Mission and Purpose; Product Development; Product Marketing; Product Launch; Product Positioning; Advertising; Business Startups; Internet and the Web; Entrepreneurship; Social Entrepreneurship; Social Issues; Social Enterprise; Retail Industry; Medical Devices and Supplies Industry; Manufacturing Industry; Health Industry; Green Technology Industry; Education Industry; Distribution Industry; Consumer Products Industry; Canada; United States; United Kingdom
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      Israeli, Ayelet. "The DivaCup: Navigating Distribution and Growth." Harvard Business School Teaching Note 523-008, July 2022.
      • July 2022
      • Teaching Plan

      Wellthy: The Economics of Caring

      By: Brian Trelstad
      Teaching Plan for HBS Case No. 320-028. In 2014, Lindsay Jurist-Rosner (MBA ’09) founded Wellthy, a B2C business that coordinates care for working professionals seeking help to support loved ones with chronic diseases or aging parents. With personal experience as a...  View Details
      Keywords: B2B Vs. B2C; Future Of Work; Health; Social Entrepreneurship; Growth and Development Strategy; Health Care and Treatment; Recruitment; Corporate Social Responsibility and Impact; Health Industry; United States
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      Trelstad, Brian. "Wellthy: The Economics of Caring." Harvard Business School Teaching Plan 322-076, July 2022.
      • June 2022
      • Teaching Plan

      Lifebank Nigeria

      By: Brian Trelstad, Pippa Tubman Armerding and Wale Lawal
      The aspiration of addressing maternal deaths in Nigeria, which were mostly caused by blood shortages, led Temie Giwa-Tubosun to found LifeBank in 2015. LifeBank developed an online platform that enabled hospitals to connect and purchase blood from local blood banks and...  View Details
      Keywords: Systems Design; Social Business; Business At The Base Of The Pyramid; Health Care; Blood; Social Enterprise; Health Care and Treatment; Growth and Development Strategy; Finance; Health Industry; Transportation Industry; Africa; Nigeria
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      Trelstad, Brian, Pippa Tubman Armerding, and Wale Lawal. "Lifebank Nigeria." Harvard Business School Teaching Plan 322-090, June 2022.
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