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  • 2021
  • Working Paper

Do Policies to Increase Access to Treatment for Opioid Use Disorder Work?
By: Eric Barrette, Leemore S. Dafny and Karen Shen
As of 2016 there were an estimated 2.1 million Americans suffering from opioid use disorder (OUD). To date, most policy interventions have focused on curbing opioid prescriptions and extending insurance coverage to include substance use disorder. However, relatively...  View Details
Keywords: Opioid Treatment; Medication-assisted Treatment; Substance Use Disorder; Private Insurance; Health Care and Treatment; Health Disorders; Insurance; United States
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  • March 2020
  • Case

The Trouble with TCE
By: Vincent Pons, Rafael Di Tella and Galit Goldstein
Trichloroethylene, or TCE, was a chemical used by tens of thousands of businesses in the United States. It was an affordable tool for many. Yet, TCE had been associated with important health risks, including cancer and autoimmune disease. TCE potentially posed other...  View Details
Keywords: Trichloroethylene; Toxicity; Lobbying; Chemicals; Health Disorders; Governing Rules, Regulations, and Reforms; Policy; Ethics; Business and Government Relations; Chemical Industry; United States
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  • 2020
  • Working Paper

Time and the Value of Data
By: Ehsan Valavi, Joel Hestness, Newsha Ardalani and Marco Iansiti
This paper investigates the effectiveness of time-dependent data in improving the quality of AI-based products and services. Time-dependency means that data loses its relevance to problems over time. This loss causes deterioration in the algorithm's performance and,...  View Details
Keywords: Economics Of AI; Machine Learning; Non-stationarity; Perishability; Value Depreciation
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  • August 2020
  • Article

Contextual Determinants of Parental Reflective Functioning: Children with Autism versus Their Typically Developing Siblings
By: Yael Enav, Dana Erhard-Weiss, Amit Goldenberg, Marguerite Knudston, Antonio Y. Hardan and James J. Gross
In this study, we examined parental reflective functioning using the Parental Developmental Interview when parents were talking about their interactions with their child with autism versus the child’s typically developing siblings. Our sample included 30 parents who...  View Details
Keywords: Autism Spectrum Disorders; Family Functioning And Support; Parents; Reflective Functioning; Siblings; Health Disorders; Family and Family Relationships
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  • Article

Treatment Of Opioid Use Disorder Among Commercially Insured U.S. Adults, 2008–17
By: Karen Shen, Eric Barrette and Leemore S. Dafny
There is abundant literature on efforts to reduce opioid prescriptions and misuse, but comparatively little on the treatment provided to people with opioid use disorder (OUD). Using claims data representing 12–15 million nonelderly adults covered through commercial...  View Details
Keywords: Opioid Treatment; Medication-assisted Treatment; Substance Use Disorder; Private Insurance; Health Disorders; Health Care and Treatment; Insurance; United States
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  • March 2020
  • Case

EyeControl: Inspiring Communication
By: Paul A. Gompers and Danielle Golan
Eye-controlled communication device startup EyeControl was founded in Tel Aviv, Israel in 2016 by cofounders with a shared personal connection to locked-in syndrome—a neurological disorder that left sufferers cognitively sound, yet paralyzed, with the exception of eye...  View Details
Keywords: Health Disorders; Communication Technology; Business Startups; Expansion; Finance; Decision Making; Social Enterprise; Medical Devices and Supplies Industry
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  • 2019
  • Working Paper

Throwing the Baby Out with the Drinking Water: Unintended Consequences of Arsenic Mitigation Efforts in Bangladesh
By: Nina Buchmann, Erica Field, Rachel Glennerster and Reshmaan Hussam
The 1994 discovery of arsenic in ground water in Bangladesh prompted a massive public health effort to test all tubewells in the country and convince nearly one-quarter of the population to switch to arsenic-free drinking water sources. According to numerous sources,...  View Details
Keywords: Child Mortality; Arsenic; Unintended Consequences; Health Disorders; Safety; Outcome or Result; Bangladesh
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  • August 21, 2018
  • Article

Patient–Physician Gender Concordance and Increased Mortality Among Female Heart Attack Patients
By: Brad Greenwood, Seth Carnahan and Laura Huang
We examine patient gender disparities in survival rates following acute myocardial infarctions (i.e., heart attacks) based on the gender of the treating physician. Using a census of heart attack patients admitted to Florida hospitals between 1991 and 2010, we find...  View Details
Keywords: Health Disorders; Health Care and Treatment; Gender; Outcome or Result
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  • Article

TDABC Cost Analysis of Ocular Disorders in an Ophthalmology Emergency Department versus Urgent Care: Clinical Experience at Massachusetts Eye and Ear
By: Robert S. Kaplan, Jonathan Chou, Mahek Shah, Amy Watts, Matthew Gardiner, Joan Miller and John I. Lowenstein
Purpose  To perform a cost analysis comparison for managing common ocular disorders in an eye emergency department (ED) versus an urgent care setting using a time-driven activity-based cost model (TDABC) to assist physicians and staff in appropriate allocation of...  View Details
Keywords: Time-driven Activity-based Cost Model; Emergency Room; Urgent Care Clinic; Cost; Analysis; Activity Based Costing and Management; Health Care and Treatment
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  • 2017
  • Chapter

High Stakes Negotiation: Indian Gaming and Tribal/State Compacts
By: Gavin Clarkson and James K. Sebenius
Although Indian tribes and the surrounding states were often bitter enemies throughout much of the history of the United States, recently tribes and states have been able to work cooperatively in a number of areas. In some instances, Congress has mandated such...  View Details
Keywords: Indian Gaming; Negotiation; Regulation; Tribal Sovereignty; Sovereign Finance; Negotiation Participants; Relationships; Cooperation; Connecticut
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  • Article

Neurodiversity as a Competitive Advantage
By: Robert D. Austin and Gary P. Pisano
Many people with neurological conditions such as autism spectrum disorder and dyslexia have extraordinary skills, including those in pattern recognition, memory, and mathematics. Yet they often struggle to fit the profiles sought by employers. A growing number of...  View Details
Keywords: Competitive Advantage; Diversity; Competency and Skills
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  • April 2017
  • Case

Luminopia: Improving Treatment for Visual Disorders
By: Doug J. Chung and Sarah Mehta
Luminopia—a start-up founded in January 2016 by three Harvard College freshmen—uses virtual reality technology to treat amblyopia (more commonly called “lazy eye”), the single biggest cause of visual disorders among children. By February 2017, the three founders had...  View Details
Keywords: Pricing; Virtual Reality; Startup; Marketing; Marketing Channels; Product Marketing; Product Launch; Product Positioning; Business Startups; Price; Medical Devices and Supplies Industry; Cambridge; Massachusetts; United States
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  • October 2016
  • Case

Addicaid: Scaling a Digital Platform for Addiction Wellness and Recovery
By: Robert S. Huckman and Sarah Mehta
In 2013, Sam Frons founded Addicaid—a mobile application (app) that allowed people in addiction recovery to track their progress, check in with counselors, and connect with others in recovery programs. The app was grounded in cognitive behavioral therapy and used the...  View Details
Keywords: Digital Health Interventions; Substance Use Disorder; Addiction Treatment; Addiction Recovery; Scale; Innovation; Health; Health Disorders; Health Industry; New York (city, NY)
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  • Article

Time-driven Activity-based Costing of Multivessel Coronary Artery Bypass Grafting across National Boundaries to Identify Improvement Opportunities: Study Protocol
By: F. Erhun, B. Mistry, T. Platcheck, A. Milstein, V.G. Narayanan and R. S. Kaplan
Coronary artery bypass graft (CABG) surgery is a common treatment for coronary artery disease—a disease that affects over 10% of US adults and is a major cause of morbidity and mortality. In 2005, the mean cost for a CABG procedure among Medicare beneficiaries in the...  View Details
Keywords: Activity Based Costing and Management; Health Disorders; Health Care and Treatment; United States; India
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  • Article

Patterns of Failure after Involved Field Radiation Therapy for Pediatric and Young Adult Hodgkin Lymphoma
By: Minh-Phuong Huynh-Le, Amanda J. Walker, Scott Duke Kominers, Ido Paz-Priel, Moody D. Wharam and Stephanie A. Terezakis
Involved field radiation therapy (IFRT) is integral in curative therapy for Hodgkin lymphoma (HL), although primarily used in patients with intermediate/high‐risk HL. We present failure patterns and clinical outcomes in a cohort of pediatric and young adult patients...  View Details
Keywords: Hematology/oncology; Hodgkin Lymphoma; Involved Field Radiation Therapy; Health Disorders; Health Care and Treatment
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  • March 2014
  • Editorial

Limits on Use of Health Economic Assessments for Rare Diseases
By: Hanna I. Hyry, Ariel Dora Stern, Jonathan CP Roos and Timothy M. Cox
Funding of expensive treatments for rare ('orphan') diseases is contentious. These agents fare poorly on 'efficiency' or health economic measures, such as the QALY, because of high cost and frequently poor gains in quality of life and survival. We show that...  View Details
Keywords: Cost; Health Disorders; Health Care and Treatment; Pharmaceutical Industry
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  • January 2014
  • Teaching Note

Dr. Benjamin Hooks and Children's Health Forum
By: Rosabeth Moss Kanter and Ai-Ling Malone
The case includes law, business, and public health perspectives on an African American leader's social entrepreneurship and leadership in other social movements. Later in his life, Dr. Benjamin Hooks championed the eradication of lead poisoning. Prior to that Hooks...  View Details
Keywords: Leading Change; Health Disorders; Social Entrepreneurship; Personal Development and Career; Social Issues; United States
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  • April 2013
  • Article

What Roger Fisher Got Profoundly Right: Five Enduring Lessons for Negotiators
By: James K. Sebenius
Roger Fisher, who died in 2012, enjoyed a remarkable career that modeled one way that an academic, especially in a professional school such as law or business, could make a significant, positive, and lasting difference in the world. Distinctive aspects of his career...  View Details
Keywords: Bargaining; Conflict Resolution; Dealmaking; Negotiation; Personal Development and Career; Conflict and Resolution
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  • Article

Putting Patients First: Social Marketing Strategies for Treating HIV in Developing Nations
By: Zoe Chance and Rohit Deshpandé
It is more than mere coincidence that the highest rates of HIV occur in the world's poorest countries. Of the over 40 million people currently living with HIV, 95 percent are in the developing world. The first part of this paper explores the economics of HIV and...  View Details
Keywords: Health Disorders; Developing Countries and Economies; Poverty; Health Care and Treatment; Social Marketing; Perspective; Customer Focus and Relationships; Profit; Africa; Asia; South America
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  • March 2003
  • Article

Technological Development and Medical Productivity: The Diffusion of Angioplasty in New York State
By: David M. Cutler and Robert S. Huckman
A puzzling feature of many medical innovations is that they simultaneously appear to reduce unit costs and increase total costs. We consider this phenomenon by examining the diffusion of percutaneous transluminal coronary angioplasty (PTCA)—a treatment for coronary...  View Details
Keywords: Innovation and Invention; Cost; Health Care and Treatment; Health Disorders; Performance Improvement; Product; New York (state, US)
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