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- 2022
- Working Paper
Laboratory Safety and Research Productivity
By: Alberto Galasso, Hong Luo and Brooklynn Zhu
Are laboratory safety practices a tax on scientific productivity? We examine this question by exploiting the substantial increase in safety regulations at the University of California following the shocking accidental death of a research assistant in 2008....
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Keywords:
Economics Of Science;
Risk Perception;
Safety Regulations;
Safety;
Working Conditions;
Governing Rules, Regulations, and Reforms;
Innovation and Invention
Galasso, Alberto, Hong Luo, and Brooklynn Zhu. "Laboratory Safety and Research Productivity." Harvard Business School Working Paper, No. 22-072, May 2022.
- 2021
- Working Paper
Do Policies to Increase Access to Treatment for Opioid Use Disorder Work?
By: Eric Barrette, Leemore S. Dafny and Karen Shen
As of 2016 there were an estimated 2.1 million Americans suffering from opioid use disorder (OUD). To date, most policy interventions have focused on curbing opioid prescriptions and extending insurance coverage to include substance use disorder. However, relatively...
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Keywords:
Opioid Treatment;
Medication-assisted Treatment;
Substance Use Disorder;
Private Insurance;
Health Care and Treatment;
Health Disorders;
Insurance;
United States
Barrette, Eric, Leemore S. Dafny, and Karen Shen. "Do Policies to Increase Access to Treatment for Opioid Use Disorder Work?" NBER Working Paper Series, No. 29001, July 2021.
- March 2020
- Case
The Trouble with TCE
By: Vincent Pons, Rafael Di Tella and Galit Goldstein
Trichloroethylene, or TCE, was a chemical used by tens of thousands of businesses in the United States. It was an affordable tool for many. Yet, TCE had been associated with important health risks, including cancer and autoimmune disease. TCE potentially posed other...
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- August 2020
- Article
Contextual Determinants of Parental Reflective Functioning: Children with Autism versus Their Typically Developing Siblings
By: Yael Enav, Dana Erhard-Weiss, Amit Goldenberg, Marguerite Knudston, Antonio Y. Hardan and James J. Gross
In this study, we examined parental reflective functioning using the Parental Developmental Interview when parents were talking about their interactions with their child with autism versus the child’s typically developing siblings. Our sample included 30 parents who...
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Keywords:
Autism Spectrum Disorders;
Family Functioning And Support;
Parents;
Reflective Functioning;
Siblings;
Health Disorders;
Family and Family Relationships
Enav, Yael, Dana Erhard-Weiss, Amit Goldenberg, Marguerite Knudston, Antonio Y. Hardan, and James J. Gross. "Contextual Determinants of Parental Reflective Functioning: Children with Autism versus Their Typically Developing Siblings." Autism 24, no. 6 (August 2020).
- Article
Treatment Of Opioid Use Disorder Among Commercially Insured U.S. Adults, 2008–17
By: Karen Shen, Eric Barrette and Leemore S. Dafny
There is abundant literature on efforts to reduce opioid prescriptions and misuse, but comparatively little on the treatment provided to people with opioid use disorder (OUD). Using claims data representing 12–15 million nonelderly adults covered through commercial...
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Keywords:
Opioid Treatment;
Medication-assisted Treatment;
Substance Use Disorder;
Private Insurance;
Health Disorders;
Health Care and Treatment;
Insurance;
United States
Shen, Karen, Eric Barrette, and Leemore S. Dafny. "Treatment Of Opioid Use Disorder Among Commercially Insured U.S. Adults, 2008–17." Health Affairs 39, no. 6 (June 2020): 993–1001.
- March 2020
- Case
EyeControl: Inspiring Communication
By: Paul A. Gompers and Danielle Golan
Eye-controlled communication device startup EyeControl was founded in Tel Aviv, Israel in 2016 by cofounders with a shared personal connection to locked-in syndrome—a neurological disorder that left sufferers cognitively sound, yet paralyzed, with the exception of eye...
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- 2019
- Working Paper
Throwing the Baby Out with the Drinking Water: Unintended Consequences of Arsenic Mitigation Efforts in Bangladesh
By: Nina Buchmann, Erica Field, Rachel Glennerster and Reshmaan Hussam
The 1994 discovery of arsenic in ground water in Bangladesh prompted a massive public health effort to test all tubewells in the country and convince nearly one-quarter of the population to switch to arsenic-free drinking water sources. According to numerous sources,...
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Keywords:
Child Mortality;
Arsenic;
Unintended Consequences;
Health Disorders;
Safety;
Outcome or Result;
Bangladesh
Buchmann, Nina, Erica Field, Rachel Glennerster, and Reshmaan Hussam. "Throwing the Baby Out with the Drinking Water: Unintended Consequences of Arsenic Mitigation Efforts in Bangladesh." NBER Working Paper Series, No. 25729, April 2019.
- August 21, 2018
- Article
Patient–Physician Gender Concordance and Increased Mortality Among Female Heart Attack Patients
By: Brad Greenwood, Seth Carnahan and Laura Huang
We examine patient gender disparities in survival rates following acute myocardial infarctions (i.e., heart attacks) based on the gender of the treating physician. Using a census of heart attack patients admitted to Florida hospitals between 1991 and 2010, we find...
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Greenwood, Brad, Seth Carnahan, and Laura Huang. "Patient–Physician Gender Concordance and Increased Mortality Among Female Heart Attack Patients." Proceedings of the National Academy of Sciences 115, no. 34 (August 21, 2018).
- Article
TDABC Cost Analysis of Ocular Disorders in an Ophthalmology Emergency Department versus Urgent Care: Clinical Experience at Massachusetts Eye and Ear
By: Robert S. Kaplan, Jonathan Chou, Mahek Shah, Amy Watts, Matthew Gardiner, Joan Miller and John I. Lowenstein
Purpose
To perform a cost analysis comparison for managing common ocular disorders in an eye emergency department (ED) versus an urgent care setting using a time-driven activity-based cost model (TDABC) to assist physicians and staff in appropriate allocation of...
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Keywords:
Time-driven Activity-based Cost Model;
Emergency Room;
Urgent Care Clinic;
Cost;
Analysis;
Activity Based Costing and Management;
Health Care and Treatment
Kaplan, Robert S., Jonathan Chou, Mahek Shah, Amy Watts, Matthew Gardiner, Joan Miller, and John I. Lowenstein. "TDABC Cost Analysis of Ocular Disorders in an Ophthalmology Emergency Department versus Urgent Care: Clinical Experience at Massachusetts Eye and Ear." Journal of Academic Ophthalmology 10 (2018).
- 2017
- Chapter
High Stakes Negotiation: Indian Gaming and Tribal/State Compacts
By: Gavin Clarkson and James K. Sebenius
Although Indian tribes and the surrounding states were often bitter enemies throughout much of the history of the United States, recently tribes and states have been able to work cooperatively in a number of areas. In some instances, Congress has mandated such...
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Keywords:
Indian Gaming;
Negotiation;
Regulation;
Tribal Sovereignty;
Sovereign Finance;
Negotiation Participants;
Relationships;
Cooperation;
Connecticut
Clarkson, Gavin, and James K. Sebenius. "High Stakes Negotiation: Indian Gaming and Tribal/State Compacts." Chap. 8 in American Indian Business: Principles and Practices, edited by Deanna M. Kennedy, Charles Harrington, Amy Klemm Verbos, Daniel Stewart, Joseph Gladstone, and Gavin Clarkson, 130–161. Seattle: University of Washington Press, 2017.
- Article
Neurodiversity as a Competitive Advantage
By: Robert D. Austin and Gary P. Pisano
Many people with neurological conditions such as autism spectrum disorder and dyslexia have extraordinary skills, including those in pattern recognition, memory, and mathematics. Yet they often struggle to fit the profiles sought by employers. A growing number of...
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Austin, Robert D., and Gary P. Pisano. "Neurodiversity as a Competitive Advantage." Harvard Business Review 95, no. 3 (May–June 2017): 96–103.
- April 2017
- Case
Luminopia: Improving Treatment for Visual Disorders
By: Doug J. Chung and Sarah Mehta
Luminopia—a start-up founded in January 2016 by three Harvard College freshmen—uses virtual reality technology to treat amblyopia (more commonly called “lazy eye”), the single biggest cause of visual disorders among children. By February 2017, the three founders had...
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Keywords:
Pricing;
Virtual Reality;
Startup;
Marketing;
Marketing Channels;
Product Marketing;
Product Launch;
Product Positioning;
Business Startups;
Price;
Medical Devices and Supplies Industry;
Cambridge;
Massachusetts;
United States
Chung, Doug J., and Sarah Mehta. "Luminopia: Improving Treatment for Visual Disorders." Harvard Business School Case 517-065, April 2017.
- October 2016
- Case
Addicaid: Scaling a Digital Platform for Addiction Wellness and Recovery
By: Robert S. Huckman and Sarah Mehta
In 2013, Sam Frons founded Addicaid—a mobile application (app) that allowed people in addiction recovery to track their progress, check in with counselors, and connect with others in recovery programs. The app was grounded in cognitive behavioral therapy and used the...
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Keywords:
Digital Health Interventions;
Substance Use Disorder;
Addiction Treatment;
Addiction Recovery;
Scale;
Innovation;
Health;
Health Disorders;
Health Industry;
New York (city, NY)
Huckman, Robert S., and Sarah Mehta. "Addicaid: Scaling a Digital Platform for Addiction Wellness and Recovery." Harvard Business School Case 617-018, October 2016.
- Article
Time-driven Activity-based Costing of Multivessel Coronary Artery Bypass Grafting across National Boundaries to Identify Improvement Opportunities: Study Protocol
By: F. Erhun, B. Mistry, T. Platcheck, A. Milstein, V.G. Narayanan and R. S. Kaplan
Coronary artery bypass graft (CABG) surgery is a common treatment for coronary artery disease—a disease that affects over 10% of US adults and is a major cause of morbidity and mortality. In 2005, the mean cost for a CABG procedure among Medicare beneficiaries in the...
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Keywords:
Activity Based Costing and Management;
Health Disorders;
Health Care and Treatment;
United States;
India
Erhun, F., B. Mistry, T. Platcheck, A. Milstein, V.G. Narayanan, and R. S. Kaplan. "Time-driven Activity-based Costing of Multivessel Coronary Artery Bypass Grafting across National Boundaries to Identify Improvement Opportunities: Study Protocol." BMJ Open 5, no. 8 (2015).
- Article
Patterns of Failure after Involved Field Radiation Therapy for Pediatric and Young Adult Hodgkin Lymphoma
By: Minh-Phuong Huynh-Le, Amanda J. Walker, Scott Duke Kominers, Ido Paz-Priel, Moody D. Wharam and Stephanie A. Terezakis
Involved field radiation therapy (IFRT) is integral in curative therapy for Hodgkin lymphoma (HL), although primarily used in patients with intermediate/high‐risk HL. We present failure patterns and clinical outcomes in a cohort of pediatric and young adult patients...
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Keywords:
Hematology/oncology;
Hodgkin Lymphoma;
Involved Field Radiation Therapy;
Health Disorders;
Health Care and Treatment
Huynh-Le, Minh-Phuong, Amanda J. Walker, Scott Duke Kominers, Ido Paz-Priel, Moody D. Wharam, and Stephanie A. Terezakis. "Patterns of Failure after Involved Field Radiation Therapy for Pediatric and Young Adult Hodgkin Lymphoma." Pediatric Blood & Cancer 61, no. 7 (July 2014).
- March 2014
- Editorial
Limits on Use of Health Economic Assessments for Rare Diseases
By: Hanna I. Hyry, Ariel Dora Stern, Jonathan CP Roos and Timothy M. Cox
Funding of expensive treatments for rare ('orphan') diseases is contentious. These agents fare poorly on 'efficiency' or health economic measures, such as the QALY, because of high cost and frequently poor gains in quality of life and survival. We show that...
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Hyry, Hanna I., Ariel Dora Stern, Jonathan CP Roos, and Timothy M. Cox. "Limits on Use of Health Economic Assessments for Rare Diseases." hcu016. QJM: An International Journal of Medicine 107, no. 3 (March 2014): 241–245.
- January 2014
- Teaching Note
Dr. Benjamin Hooks and Children's Health Forum
By: Rosabeth Moss Kanter and Ai-Ling Malone
The case includes law, business, and public health perspectives on an African American leader's social entrepreneurship and leadership in other social movements. Later in his life, Dr. Benjamin Hooks championed the eradication of lead poisoning. Prior to that Hooks...
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- April 2013
- Article
What Roger Fisher Got Profoundly Right: Five Enduring Lessons for Negotiators
Roger Fisher, who died in 2012, enjoyed a remarkable career that modeled one way that an academic, especially in a professional school such as law or business, could make a significant, positive, and lasting difference in the world. Distinctive aspects of his career...
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Keywords:
Bargaining;
Conflict Resolution;
Dealmaking;
Negotiation;
Personal Development and Career;
Conflict and Resolution
Sebenius, James K. "What Roger Fisher Got Profoundly Right: Five Enduring Lessons for Negotiators." Negotiation Journal 29, no. 2 (April 2013): 159–169.
- Article
Putting Patients First: Social Marketing Strategies for Treating HIV in Developing Nations
By: Zoe Chance and Rohit Deshpandé
It is more than mere coincidence that the highest rates of HIV occur in the world's poorest countries. Of the over 40 million people currently living with HIV, 95 percent are in the developing world. The first part of this paper explores the economics of HIV and...
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Keywords:
Health Disorders;
Developing Countries and Economies;
Poverty;
Health Care and Treatment;
Social Marketing;
Perspective;
Customer Focus and Relationships;
Profit;
Africa;
Asia;
South America
Chance, Zoe, and Rohit Deshpandé. "Putting Patients First: Social Marketing Strategies for Treating HIV in Developing Nations." Special Issue on Metric and Interpretive Explorations of Macromarketing. Journal of Macromarketing 29, no. 3 (September 2009).
- August 2003 (Revised January 2021)
- Case
Fighting the Battle of the Bulge—Evaluating Innovations in Morbid Obesity Treatment
By: Regina E. Herzlinger and John McDonough
What can Dr. Dean Ornish learn from the successes and failures of his competitors to create a business model that will “do good” by combatting obesity and associated chronic diseases and “do well” by growing a widely adopted business? While the market for weight loss...
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Keywords:
Three Pillars;
Industry Analysis;
Health Disorders;
Health Care and Treatment;
Innovation and Invention;
Business Model;
Analysis;
Innovation and Management;
Medical Specialties;
Health Industry
Herzlinger, Regina E., and John McDonough. "Fighting the Battle of the Bulge—Evaluating Innovations in Morbid Obesity Treatment." Harvard Business School Case 304-009, August 2003. (Revised January 2021.)