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- 2022
- Working Paper
Laboratory Safety and Research Productivity
By: Alberto Galasso, Hong Luo and Brooklynn Zhu
Are laboratory safety practices a tax on scientific productivity? We examine this question by exploiting the substantial increase in safety regulations at the University of California following the shocking accidental death of a research assistant in 2008....
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- April 27, 2022
- Article
Inequality in Researchers' Minds: Four Guiding Questions for Studying Subjective Perceptions of Economic Inequality
By: Jon M. Jachimowicz, Shai Davidai, Daniela Goya-Tocchetto, Barnabas Szaszi, Martin Day, Stephanie Tepper, L. Taylor Phillips, M. Usman Mirza, Nailya Ordabayeva and Oliver P. Hauser
Subjective perceptions of inequality can substantially influence policy attitudes, public health metrics, and societal well-being, but the lack of consensus in the scientific community on how to best operationalize and measure these perceptions may impede progress on...
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- 2021
- Working Paper
How Important is Editorial Gatekeeping? Evidence from Top Biomedical Journals
We examine editors' influence on the scientific content of academic journals by unpacking the role of three major forces: journals' missions, aggregate supply of and demand for specific topics, and scientific homophily via editorial gatekeeping. In a sample of top...
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- Article
Measuring the Scientific Effectiveness of Contact Tracing: Evidence from a Natural Experiment
By: Thiemo Fetzer and Thomas Graeber
Contact tracing has for decades been a cornerstone of the public health approach to epidemics, including Ebola, severe acute respiratory syndrome, and now COVID-19. It has not yet been possible, however, to causally assess the method’s effectiveness using a randomized...
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- 2022
- Working Paper
Standing on the Shoulders of Science
By: Joshua Lev Krieger, Monika Schnitzer and Martin Watzinger
Today's innovations rely on scientific discoveries of the past, yet only some corporate R&D builds directly on scientific output. In this paper, we analyze U.S. patents to investigate how firms generate value by building on prior art "closer" to science and establish...
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- May 2021
- Case
The SMA Foundation: Steering Therapeutic Research and Development in a Rare Disease
By: Amitabh Chandra, Spencer Lee-Rey and Caroline Marra
This case explores incentives for rare disease drug development by chronicling the role of the Spinal Muscular Atrophy (SMA) Foundation in forming strategic partnerships with the scientific research community and pharmaceutical developers to transform the trajectory...
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- January–February 2021
- Article
Food and Drug Administration Guidance Documents and New Medical Devices: The Case of Breast Prostheses
By: Rachel E. Weitzman, Ariel Dora Stern and Daniel B. Kramer
As pressure mounts on the Food and Drug Administration (FDA) to speed its review process for novel devices, and budgetary pressures further strain its resources, the critical role of guidance documents in assuring consistent, rigorous, and scientifically grounded...
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- Article
Assessing the Food and Drug Administration's Risk-Based Framework for Software Precertification with Top Health Apps in the United States: Quality Improvement Study
By: Noy Alon, Ariel Dora Stern and John Torous
BACKGROUND: As the development of mobile health apps continues to accelerate, the need to implement a framework that can standardize categorizing these apps to allow for efficient, yet robust regulation grows. However, regulators and researchers are faced with numerous...
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- November 9, 2019
- Article
Effect of Revealing Authors' Conflicts of Interests in Peer Review: Randomized Controlled Trial
By: Leslie K. John, George Loewenstein, Andrew Marder and Michael Callaham
Objective: To assess the impact of disclosing authors’ conflict of interest declarations to peer reviewers at a medical journal.
Design: Randomised controlled trial.
Setting: The study was conducted within the manuscript review process at the... View Details
Design: Randomised controlled trial.
Setting: The study was conducted within the manuscript review process at the... View Details
- 2018
- Book
Food Citizenship: Food System Advocates in an Era of Distrust
By: Ray A. Goldberg
The global food system is the largest segment of the world's economy. As agribusiness-studies pioneer Ray Goldberg suggests, it is also the largest health system on the planet. And it is changing fast. Its size and importance to human, environmental, and economic...
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- 2016
- Book
Building a Culture of Health: A New Imperative for Business
By: John A. Quelch and Emily C. Boudreau
This ambitious volume sets out to understand how every company impacts public health and introduces a robust model, rooted in organizational and scientific knowledge, for companies committed to making positive contributions to health and wellness. Focusing on four...
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- February 2016
- Article
Bridging Science and Technology Through Academic-Industry Partnerships
By: Sen Chai and Willy C. Shih
Partnerships that foster the translation of scientific advances emerging from academic research organizations into commercialized products at private firms are a policy tool that has attracted increased interest. This paper examines empirical data from the Danish...
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- November 2014 (Revised March 2015)
- Case
Disrupting the Meat Industry: Tissue Culture Beef
By: Jose B. Alvarez and Matthew G. Preble
Dr. Mark Post and his team at Maastricht University were perfecting their tissue culture beef product—made entirely from muscle grown in his lab—to give it the same taste, texture and appearance of a traditional beef hamburger. A previous iteration of this product had...
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Keywords:
Innovation;
Beef Production;
Environmental Impacts Of Food Production;
Agribusiness;
Animal-Based Agribusiness;
Disruptive Innovation;
Innovation and Invention;
Environmental Sustainability;
Food;
Agriculture and Agribusiness Industry;
Food and Beverage Industry;
Netherlands;
United States;
United Kingdom
- 2014
- Working Paper
The Organizational and Geographic Drivers of Absorptive Capacity: An Empirical Analysis of Pharmaceutical R&D Laboratories
By: Francesca Lazzeri and Gary P. Pisano
Scholars and practitioners alike now recognize that a firm's capacity to assimilate and use know-how from external sources—what Cohen and Levinthal (1990) called "absorptive capacity"—plays a central role in innovation performance. In recent years, a common strategy...
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- September 2013
- Article
Prizes, Publicity, and Patents: Non-Monetary Awards as a Mechanism to Encourage Innovation
By: Petra Moser and Tom Nicholas
This paper exploits the selection of prize-winning technologies among exhibitors at the Crystal Palace Exhibition in 1851 to examine whether—and how—ex post prizes that are awarded to high-quality innovations may encourage future innovation. U.S. patent data...
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- 2014
- Working Paper
Bridging Science and Technology Through Academic-Industry Partnerships
By: Sen Chai and Willy C. Shih
Scientific research and its translation into commercialized technology is a driver of wealth creation and economic growth. Partnerships to foster the translational processes from public research organizations, such as universities and hospitals, to private firms are a...
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- April 2012
- Case
Danish National Advanced Technology Foundation
By: Willy Shih and Margaret Pierson
Danish National Advanced Technology Foundation (DNATF), a government agency, invests in public-private partnerships to stimulate commercialization of Danish scientific research within the country's industry. DNATF established a process for evaluating proposals, making...
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- 2010
- Working Paper
Boundary Spanning in a For-profit Research Lab: An Exploration of the Interface Between Commerce and Academe
By: Christopher C. Liu and Toby E. Stuart
In innovative industries, private-sector companies increasingly are participants in open communities of science and technology. To participate in the system of exchange in such communities, firms often publicly disclose what would otherwise remain private discoveries....
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- July–August 2008
- Article
Interview with a Quality Leader: Regina E. Herzlinger on Consumer-Driven Healthcare
Regina E. Herzlinger is the Nancy R. McPherson Professor of Business Administration Chair at the Harvard Business School, Cambridge, MA. She received her bachelor's degree from MIT and her doctorate from the Harvard Business School The first woman to be tenured and...
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- May 2008 (Revised May 2008)
- Case
Symyx Technologies, Inc.
By: H. Kent Bowen, Courtney Purrington and Thomas D. Perry
Symyx is a science-based company spun out of Berkeley. Its unique materials technology has been exploited for 10 years, but the company needs a new business model. The company concept required the invention of hardware and software to do high throughput materials...
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