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      • January 2023
      • Case

      Cleave Therapeutics: Taking a Risk on Oncology Drug Discovery

      By: Regina Herzlinger and Brian Walker
      How can a successful executive assess her next move as the CEO of a firm with a promising and yet uncertain new drug? Amy Burroughs’ mandate to find a therapeutic window for Cleave Therapeutics oncology drug was on track but faced an uncertain future. Overseeing the...  View Details
      Keywords: Product Development; Leadership; Health Testing and Trials; Research and Development; Risk and Uncertainty; Financial Condition; Partners and Partnerships; Pharmaceutical Industry
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      Herzlinger, Regina, and Brian Walker. "Cleave Therapeutics: Taking a Risk on Oncology Drug Discovery." Harvard Business School Case 323-045, January 2023.
      • November 2022
      • Case

      Ajax Health: A New Model for Medical Technology Innovation

      By: Regina E. Herzlinger and Ben Creo
      This case teaches key success factors for both startups and established medtech firms. It examines how to structure a firm to maximize financial returns. Medtech entrepreneur Duke Rohlen is proposing a new model for innovation and business growth. From 2007 to 2019,...  View Details
      Keywords: Business Startups; Success; Innovation Strategy; Mergers and Acquisitions; Market Entry and Exit; Financial Strategy; Business Model; Partners and Partnerships; Entrepreneurship; Private Equity; Technology Industry; Medical Devices and Supplies Industry
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      Herzlinger, Regina E., and Ben Creo. "Ajax Health: A New Model for Medical Technology Innovation." Harvard Business School Case 323-043, November 2022.
      • August 2022 (Revised November 2022)
      • Case

      Altos Ventures (A)

      By: Jo Tango and Alys Ferragamo
      In December 2012, Altos Ventures General Partners Han Kim, Anthony Lee, and Ho Nam met to discuss the future of the firm. Altos had already adjusted its strategy multiple times. It began as a U.S.-focused venture capital investor whose first two funds were backed by a...  View Details
      Keywords: Strategic Planning; Venture Capital; Investment Portfolio; Partners and Partnerships
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      Tango, Jo, and Alys Ferragamo. "Altos Ventures (A)." Harvard Business School Case 823-035, August 2022. (Revised November 2022.)
      • Article

      Creating High-Impact Coalitions: CEOs Can Lead the Charge on Society’s Biggest Problems

      By: Rosabeth M. Kanter and Tuna Cem Hayirli
      Traditionally, responses to crises and societal problems—the COVID-19 pandemic, natural disasters, racial inequities—are considered the responsibility of the public sector and NGOs. But addressing the world’s most critical problems requires leadership, resources, and...  View Details
      Keywords: Coalition; Change; Problem Solving; Organization; Boundaries; Evolution; Mission; Moral Leadership; Balance; "Solutions Approach; Society; Problems and Challenges; Organizations; Mission and Purpose; Leading Change; Trust
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      Kanter, Rosabeth M., and Tuna Cem Hayirli. "Creating High-Impact Coalitions: CEOs Can Lead the Charge on Society’s Biggest Problems." Harvard Business Review 100, no. 2 (March–April 2022).
      • March 2022 (Revised January 2023)
      • Case

      Clara Wu Tsai and Brooklyn Loan Innovation

      By: Archie L. Jones, Jeffrey J. Bussgang and Henry McGee
      Philanthropist Clara Wu Tsai is committed to racial equity and investing in Brooklyn-based minority business owners. In the wake of the George Floyd murder, she decides to create a new initiative called the Social Justice Fund and commit an initial $50 million over 10...  View Details
      Keywords: Minority-owned Businesses; Racial Equity; Entrepreneurship; Race; Values and Beliefs; Small Business; Partners and Partnerships; Social Issues; Investment; Corporate Social Responsibility and Impact; Decision Making; Brooklyn
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      Jones, Archie L., Jeffrey J. Bussgang, and Henry McGee. "Clara Wu Tsai and Brooklyn Loan Innovation." Harvard Business School Case 822-124, March 2022. (Revised January 2023.)
      • November 2021
      • Case

      Hitting Home: Amazon and Mary's Place

      By: Paul M. Healy, Debora L. Spar and Amy Klopfenstein
      In 2020, Amazon, the $386 billion online retail behemoth, built an eight-story shelter for women and families experiencing homelessness on its expanding headquarters in Seattle, Washington. The shelter, operated in partnership with a non-profit organization known as...  View Details
      Keywords: Business Ethics; Homelessness; Business And Society; Corporate Social Responsibility and Impact; Social Issues; Corporate Accountability; Urban Development; Society; Information Technology; Ethics; Technology Industry; Seattle; United States; North America
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      Healy, Paul M., Debora L. Spar, and Amy Klopfenstein. "Hitting Home: Amazon and Mary's Place." Harvard Business School Case 122-017, November 2021.
      • October 2021 (Revised February 2022)
      • Case

      upGrad: Delivering Career Outcomes Online: Degree by Degree

      By: John J-H Kim, Anjali Raina and Rachna Chawla
      In August 2021, the founders of upGrad, the latest unicorn in the Indian higher education online space, were deciding how to best use the funds to execute on their ambitious growth plans. Ronnie Screwvala, Mayank Kumar and Phalgun Kompalli had envisioned upGrad as an...  View Details
      Keywords: Unicorns; COVID-19 Pandemic; Higher Education; Internet and the Web; Spending; Growth and Development Strategy; Education Industry; India
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      Kim, John J-H, Anjali Raina, and Rachna Chawla. "upGrad: Delivering Career Outcomes Online: Degree by Degree." Harvard Business School Case 322-054, October 2021. (Revised February 2022.)
      • August 2021
      • Case

      Andreessen Horowitz’s Cultural Leadership Fund (A)

      By: Anita Elberse, Briana Richardson and Cydni Williams
      In May 2020, Chris Lyons, a partner at leading venture capital firm Andreessen Horowitz receives the news that his company has reached a verbal agreement with one of Silicon Valley’s hottest social-media startups to lead its ‘Series A’ funding round, in a deal that...  View Details
      Keywords: Entertainment; Talent Management; General Management; Inclusion; Talent and Talent Management; Diversity; Venture Capital; Entrepreneurship; Networks; Nonprofit Organizations
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      Elberse, Anita, Briana Richardson, and Cydni Williams. "Andreessen Horowitz’s Cultural Leadership Fund (A)." Harvard Business School Case 522-020, August 2021.
      • June 2021 (Revised December 2021)
      • Case

      The Lunar Gateway, Moon vs. Mars, and the Political Governance of Space Activities

      By: Matthew C. Weinzierl and Mehak Sarang
      In 2017, the Trump Administration made a bold claim—that they would return the next man and the first woman to the lunar surface by 2024, this time to establish a sustainable presence to enable further exploration in the solar system. With the Artemis Program, NASA has...  View Details
      Keywords: Space; Space Economy; Aerospace; Nasa; Governance; Policy; International Relations; Infrastructure
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      Weinzierl, Matthew C., and Mehak Sarang. "The Lunar Gateway, Moon vs. Mars, and the Political Governance of Space Activities." Harvard Business School Case 721-059, June 2021. (Revised December 2021.)
      • June 2021
      • Case

      Akira Fukabori and Kevin Kajitani at avatarin (A)

      By: Linda A. Hill and Emily Tedards
      In 2016, Akira Fukabori and Kevin Kajitani, aeronautical engineers at All Nippon Airways Co., Ltd., began to wonder why, in a world of accelerating globalization and digital connectivity, those who lived in far-remote villages or impoverished urban areas could not...  View Details
      Keywords: Agility; Ecosystem; Innovation Ecosystems; Crowdsourcing; Open Innovation; Partnership; Government; Collaboration; Co-creation; Purpose; Impact; Social Impact; Movement; Organizational Behavior; Organizational Ambidexterity; Ambidexterity; Culture; Culture Change; Global Teams; Experimentation; Space; Airline Industry; Start-up; Platform Business; Platform Strategy; Platform; Digital; Robotics; Robots; Mobility; Strategy; COVID-19; Intrapreneurship; Public-private Partnership; XPRIZE; Space Industry; Avatar; Telepresence; Innovation Lab; Innovation and Invention; Technological Innovation; Partners and Partnerships; Collaborative Innovation and Invention; Alignment; Leadership; Leading Change; Diversity; Organizational Culture; Change Management; Entrepreneurship; Digital Platforms; Transportation Industry; Aerospace Industry; Japan
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      Hill, Linda A., and Emily Tedards. "Akira Fukabori and Kevin Kajitani at avatarin (A)." Harvard Business School Case 421-089, June 2021.
      • June 2021
      • Case

      Akira Fukabori and Kevin Kajitani at avatarin (A) (Abridged)

      By: Linda A. Hill and Emily Tedards
      In 2016, Akira Fukabori and Kevin Kajitani, aeronautical engineers at All Nippon Airways Co., Ltd., began to wonder why, in a world of accelerating globalization and digital connectivity, those who lived in far-remote villages or impoverished urban areas could not...  View Details
      Keywords: Agility; Ecosystem; Innovation Ecosystems; Innovation; Crowdsourcing; XPRIZE; Open Innovation; Partnership; Government; Collaboration; Co-creation; Purpose; Impact; Social Impact; Movement; Organizational Behavior; Organizational Ambidexterity; Ambidexterity; Culture; Culture Change; Global Teams; Experimentation; Space; Space Industry; Airline Industry; Start-up; Platform Business; Platform Strategy; Platform; Digital; Robotics; Robots; Avatar; Telepresence; Innovation Lab; Mobility; COVID-19; Intrapreneurship; Public-private Partnership; Innovation and Invention; Technological Innovation; Partners and Partnerships; Collaborative Innovation and Invention; Alignment; Leadership; Leading Change; Diversity; Organizational Culture; Change Management; Strategy; Entrepreneurship; Digital Platforms; Transportation Industry; Aerospace Industry; Japan
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      Hill, Linda A., and Emily Tedards. "Akira Fukabori and Kevin Kajitani at avatarin (A) (Abridged)." Harvard Business School Case 421-085, June 2021.
      • March 2021
      • Case

      Founders Factory

      By: Jeffrey F. Rayport and James Barnett
      In January 2020, Founders Factory (FF) Executive Chairman Brent Hoberman and CEO Henry Lane Fox were considering FF’s expansion strategy. FF operated as a venture capital (VC) fund built around an accelerator and incubator, and organized around sectors within...  View Details
      Keywords: Entrepreneurship; Markets; Planning; Expansion; Global Range; Business Model; Talent and Talent Management; Experience and Expertise; Corporate Entrepreneurship; Global Strategy; Innovation Strategy; Growth and Development Strategy; Management Teams; Organizational Change and Adaptation; Partners and Partnerships; Internet and the Web; Mobile and Wireless Technology; Technology Industry; Africa; South Africa; Johannesburg; Europe; France; Paris; United Kingdom; England; London; United States; New York (city, NY)
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      Rayport, Jeffrey F., and James Barnett. "Founders Factory." Harvard Business School Case 821-009, March 2021.
      • December 2020 (Revised March 2021)
      • Case

      Made In Space, Expectations Management, and the Business of In-Space Manufacturing

      By: Matthew C. Weinzierl and Mehak Sarang
      After having proven its base technology (3D printing) through NASA solicitations and contracts, Made In Space was searching for a viable commercial application. But the business case for the leading candidate, high-quality fiber optic cable for use on Earth, remained...  View Details
      Keywords: Aerospace; Space; Space Economy; 3D Printing; Manufacturing; Public-private Partnership; Partners and Partnerships; Strategy; Business and Government Relations; Aerospace Industry; Manufacturing Industry
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      Weinzierl, Matthew C., and Mehak Sarang. "Made In Space, Expectations Management, and the Business of In-Space Manufacturing." Harvard Business School Case 721-025, December 2020. (Revised March 2021.)
      • November 2020 (Revised January 2021)
      • Supplement

      Bridge International Academies in 2020: Battling Headwinds to Solve Africa's Education Problems

      By: Caroline M. Elkins, Tarun Khanna and Joyce J. Kim
      By 2020, Bridge International Academies and its "school in a box" model had achieved great scale. By leveraging digital technology and public-private partnerships, they had reached one million children across Africa and India through hundreds of schools. However, the...  View Details
      Keywords: Entrepreneurship In Africa; Entrepreneurship In Emerging Markets; Bottom Of The Pyramid; Education In Africa; Scale; Partnerships; Education; Entrepreneurship; Emerging Markets; Health Pandemics; Problems and Challenges; Education Industry; Africa
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      Elkins, Caroline M., Tarun Khanna, and Joyce J. Kim. "Bridge International Academies in 2020: Battling Headwinds to Solve Africa's Education Problems." Harvard Business School Supplement 521-048, November 2020. (Revised January 2021.)
      • 2020
      • Working Paper

      Determinants of Early-Stage Startup Performance: Survey Results

      By: Thomas R. Eisenmann
      To explore determinants of new venture performance, the CEOs of 470 early-stage startups were surveyed regarding a broad range of factors related to their venture’s customer value proposition, product management, marketing, technology and operations, financial...  View Details
      Keywords: Startups; Survey Research; Performance Analysis; Entrepreneurship; Performance; Analysis; Business Startups; Failure; Surveys
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      Eisenmann, Thomas R. "Determinants of Early-Stage Startup Performance: Survey Results." Harvard Business School Working Paper, No. 21-057, October 2020.
      • May 2020 (Revised December 2022)
      • Case

      Soofa: Displaying the Right Path?

      By: Jeffrey J. Bussgang, Amy Klopfenstein and Amram Migdal
      In November 2019, Sandra Richter, co-founder and CEO of Soofa, a network of advertising-supported digital bulletin boards, must decide between two different fundraising and expansion plans for her company. One plan entails raising $15 million in a Series A round and...  View Details
      Keywords: Business Ventures; Business Model; Business Plan; Business Startups; Entrepreneurship; Decision Making; Decisions; Ethics; Geography; Geopolitical Units; Finance; Investment; Markets; Market Entry and Exit; Demand and Consumers; Network Effects; Media; Society; Urban Development; Sustainable Cities; Information Technology; Information Infrastructure; Digital Platforms; Strategy; Business Strategy; Expansion; Relationships; Partners and Partnerships; Capital; Venture Capital; Advertising Industry; Technology Industry; Media and Broadcasting Industry; North and Central America; United States; Massachusetts; Cambridge
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      Bussgang, Jeffrey J., Amy Klopfenstein, and Amram Migdal. "Soofa: Displaying the Right Path?" Harvard Business School Case 820-098, May 2020. (Revised December 2022.)
      • March 2020 (Revised November 2020)
      • Case

      FinTech Hive at DIFC: Creating a Fintech Ecosystem in Dubai

      By: Marco Di Maggio and Gamze Yucaoglu
      The case opens in 2019 as Raja Al Mazrouei, executive vice president of FinTech Hive (the Hive) at the Dubai International Financial Centre (DIFC), the first and largest financial technology accelerator in the Middle East, Africa and South Asia region, contemplates her...  View Details
      Keywords: Fintech; Emerging Markets; Business Startups; Venture Capital; Management; Information Technology; Growth Management; Financial Markets; Financial Institutions; United Arab Emirates; Middle East; Dubai
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      Di Maggio, Marco, and Gamze Yucaoglu. "FinTech Hive at DIFC: Creating a Fintech Ecosystem in Dubai." Harvard Business School Case 220-066, March 2020. (Revised November 2020.)
      • January 16, 2020
      • Article

      How Global Leaders Should Think About Solving Our Biggest Problems

      By: Mark R. Kramer, Marc W. Pfitzer and Helge Mahne
      The corporate social conscience will soon be on full display in Davos, Switzerland, where global leaders from business, government, and civil society will assemble on January 21 for the annual meeting of the World Economic Forum. Hundreds of millions of dollars will be...  View Details
      Keywords: Corporate Social Responsibility and Impact; Social Issues; Global Range; Partners and Partnerships; Strategy
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      Kramer, Mark R., Marc W. Pfitzer, and Helge Mahne. "How Global Leaders Should Think About Solving Our Biggest Problems." Harvard Business Review Digital Articles (January 16, 2020).
      • July 2019
      • Teaching Note

      Piramal e-Swasthya (C): A New Name, Bigger Scope, and Public-Private Partnerships

      By: Rosabeth Moss Kanter and Joyce J. Kim
      Teaching Note for HBS No. 320-012.  View Details
      Keywords: Social Entrepreneurship; Entrepreneurship; Healthcare; Innovation; Emerging Economies
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      Kanter, Rosabeth Moss, and Joyce J. Kim. "Piramal e-Swasthya (C): A New Name, Bigger Scope, and Public-Private Partnerships." Harvard Business School Teaching Note 320-014, July 2019.
      • July 2019 (Revised May 2020)
      • Supplement

      Piramal e-Swasthya (C): A New Name, Bigger Scope, and Public-Private Partnerships

      By: Rosabeth Moss Kanter and Joyce J. Kim
      In 2010, Anand Piramal acquired the Health Management Research Institute (HMRI), a healthcare venture, and merged it with his original digital healthcare startup Piramal e-Swasthya (PeS), so that PeS became Piramal Swasthya. After acquiring HMRI, Piramal Swasthya...  View Details
      Keywords: Entrepreneur; Healthcare; Innovation; Emerging Economies; Scaling; Social Enterprise; Entrepreneurship; Health Care and Treatment; Innovation and Management; Emerging Markets; Growth and Development; Organizational Change and Adaptation; Partners and Partnerships; India
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      Kanter, Rosabeth Moss, and Joyce J. Kim. "Piramal e-Swasthya (C): A New Name, Bigger Scope, and Public-Private Partnerships." Harvard Business School Supplement 320-012, July 2019. (Revised May 2020.)
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