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- February 2024
- Supplement
Seeds of Innovation: GALY’s Quest to Cultivate the Future of Agriculture in the Lab
By: George Serafeim
In 2023, Luciano Bueno, CEO and founder of plant cell culture agriculture company GALY was considering the best path forward for his company has he planned to pitch Series B investors. GALY, founded in 2019, aimed to produce cotton and
other crops from cells grown in...
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Keywords:
Strategy;
Business Model;
Green Technology;
Goods and Commodities;
Growth and Development Strategy;
Science;
Entrepreneurship;
Agriculture and Agribusiness Industry;
Technology Industry;
Boston;
Sao Paulo
Serafeim, George. "Seeds of Innovation: GALY’s Quest to Cultivate the Future of Agriculture in the Lab." Harvard Business School Multimedia/Video Supplement 124-705, February 2024.
- February 2024
- Case
AGENTS.inc: Pathways to Growth at an AI Startup
By: Frank Nagle, Manuel Hoffmann, Karoline Ströhlein and Susan Pinckney
The case describes the history of AGENTS.inc. Despite being a small startup, with only four employees, that had never had a funding round, the company boasted an impressive client portfolio including multiple Fortune 500 companies. While AGENTS.inc had been an early...
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Keywords:
Business Ventures;
Business Growth and Maturation;
Business Model;
Business Startups;
Small Business;
Change;
Transformation;
Customers;
Customer Focus and Relationships;
Decision Making;
Decisions;
Entrepreneurship;
Finance;
Venture Capital;
Financial Strategy;
Information Technology;
AI and Machine Learning;
Digital Platforms;
Technological Innovation;
Intellectual Property;
Copyright;
Management;
Growth and Development;
Markets;
Market Timing;
Ownership;
Risk and Uncertainty;
Strategy;
Competition;
Computer Industry;
Europe;
Germany
Nagle, Frank, Manuel Hoffmann, Karoline Ströhlein, and Susan Pinckney. "AGENTS.inc: Pathways to Growth at an AI Startup." Harvard Business School Case 724-444, February 2024.
- 2024
- Article
Beyond the 510(k): The Regulation of Novel Moderate-Risk Medical Devices, Intellectual Property Considerations, and Innovation Incentives in the FDA’s De Novo Pathway
By: Mateo Aboy, Cristina Crespo and Ariel Stern
Moderate-risk medical devices constitute 99% of those that have been regulated by the U.S. Food and Drug Administration (FDA) since it gained authority to regulate medical technology nearly five decades ago. This article presents an analysis of the interaction between...
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Keywords:
Governing Rules, Regulations, and Reforms;
Health Care and Treatment;
Technology Adoption;
Technological Innovation;
Safety;
Medical Devices and Supplies Industry;
United States
Aboy, Mateo, Cristina Crespo, and Ariel Stern. "Beyond the 510(k): The Regulation of Novel Moderate-Risk Medical Devices, Intellectual Property Considerations, and Innovation Incentives in the FDA’s De Novo Pathway." Art. 29. npj Digital Medicine 7 (2024).
- Working Paper
Visual Uniqueness in Peer-to-Peer Marketplaces: Machine Learning Model Development, Validation, and Application
By: Flora Feng, Charis Li and Shunyuan Zhang
Peer-to-peer (P2P) marketplaces have seen exponential growth in recent years featured by unique offerings from individual providers. Despite the perceived value of uniqueness, scalable quantification of visual uniqueness in P2P platforms like Airbnb has been largely...
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Keywords:
Peer-to-peer Markets;
Marketplace Matching;
AI and Machine Learning;
Demand and Consumers;
Digital Platforms;
Marketing
Feng, Flora, Charis Li, and Shunyuan Zhang. "Visual Uniqueness in Peer-to-Peer Marketplaces: Machine Learning Model Development, Validation, and Application." SSRN Working Paper Series, No. 4665286, February 2024.
- January 2024 (Revised January 2024)
- Case
Uncle Nearest: Creating a Legacy
By: Hise Gibson, Archie L. Jones, Nicole Gilmore and Ai-Ling Jamila Malone
Fawn Weaver, as a Black woman and industry outsider in a capital-intensive, highly regulated, competitive and male-dominated spirits industry, successfully overcame numerous obstacles to launch a premium American whiskey brand, Uncle Nearest in 2017, which became the...
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Keywords:
Advertising;
Business Startups;
Customer Focus and Relationships;
Decisions;
Forecasting and Prediction;
Age;
Ethnicity;
Gender;
Corporate Entrepreneurship;
Entrepreneurship;
Working Capital;
Innovation Leadership;
Innovation Strategy;
Intellectual Property;
Trademarks;
Leadership Style;
Growth and Development;
Growth and Development Strategy;
Marketing;
Product Marketing;
Product Launch;
Marketing Strategy;
Mission and Purpose;
Organizational Culture;
Private Ownership;
Performance Effectiveness;
Strategic Planning;
Problems and Challenges;
Prejudice and Bias;
Social Issues;
Strategy;
Competition;
Competitive Strategy;
Expansion;
Food and Beverage Industry;
Tourism Industry;
United States;
Tennessee;
France
- December 2023
- Supplement
Viceroy Research versus Medical Properties Trust
By: Jonas Heese and Joseph Pacelli
- December 2023
- Teaching Note
Viceroy Research versus Medical Properties Trust
By: Jonas Heese and Joseph Pacelli
Teaching Note for HBS Case No. 124-027.
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- 2023
- Article
Which Models Have Perceptually-Aligned Gradients? An Explanation via Off-Manifold Robustness
By: Suraj Srinivas, Sebastian Bordt and Himabindu Lakkaraju
One of the remarkable properties of robust computer vision models is that their input-gradients are often aligned with human perception, referred to in the literature as perceptually-aligned gradients (PAGs). Despite only being trained for classification, PAGs cause...
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Srinivas, Suraj, Sebastian Bordt, and Himabindu Lakkaraju. "Which Models Have Perceptually-Aligned Gradients? An Explanation via Off-Manifold Robustness." Advances in Neural Information Processing Systems (NeurIPS) (2023).
- October 2023 (Revised November 2023)
- Case
Recycle & Re-Match: The Future of Soccer Turfs
By: George Serafeim, Lena Duchene and Carlota Moniz
By August 2023, Re-Match, an artificial turf waste-to-value company, had operations in Denmark and the Netherlands and had recycled over 160,000 tons of waste and plastic fiber. With recent capital injection from the VC firm Verdane and a dual revenue business model,...
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Keywords:
Carbon Emissions;
Carbon Abatement;
Sustainability;
Recycling;
Waste Management;
Technology;
Entrepreneurial Management;
Business Growth and Maturation;
Business Model;
Decisions;
Energy Conservation;
Investment Return;
Profit;
Technological Innovation;
Patents;
Growth and Development Strategy;
Market Entry and Exit;
Digital Platforms;
Wastes and Waste Processing;
Business Strategy;
Competition;
Expansion;
Technology Adoption;
Sports;
Environmental Sustainability;
Entrepreneurship;
Green Technology Industry;
Service Industry;
Manufacturing Industry;
Rubber Industry;
Sports Industry;
Denmark;
Netherlands;
France;
United States;
Pennsylvania;
Europe
- October 2023
- Article
Innovation on Wings: When Do Nonstop Flights Matter for Global Innovation?
By: Dany Bahar, Prithwiraj Choudhury, Do Yoon Kim and Wesley Koo
We study whether, when, and how better connectivity through nonstop flights leads to positive innovation outcomes for firms in the global context. Using unique data of all flights emanating from 5,015 airports around the globe from 2005 to 2015 and exploiting a...
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Keywords:
Nonstop Flights;
Collaborative Innovation and Invention;
Patents;
Research and Development;
Air Transportation Industry
Bahar, Dany, Prithwiraj Choudhury, Do Yoon Kim, and Wesley Koo. "Innovation on Wings: When Do Nonstop Flights Matter for Global Innovation?" Management Science 69, no. 10 (October 2023): 6202–6223.
- September 2023
- Technical Note
Free and Open Source Software and Hardware
By: Frank Nagle
This technical note surveys the concepts of free and open source software and hardware. It introduces the concepts in general, providing a brief history of their development and numerous examples of how companies employ them in practice. Further, it identifies various...
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Keywords:
Corporate Strategy;
Collaborative Innovation and Invention;
Technological Innovation;
Nonprofit Organizations;
Competitive Strategy;
Patents;
Information Technology;
Business Model;
Open Source Distribution;
Applications and Software;
Information Technology Industry;
Technology Industry
Nagle, Frank. "Free and Open Source Software and Hardware." Harvard Business School Technical Note 724-380, September 2023.
- September 2023 (Revised November 2023)
- Case
Seeds of Innovation: GALY's Quest to Cultivate the Future of Agriculture in the Lab
By: George Serafeim and Michael Norris
In 2023, Luciano Bueno, CEO and founder of plant cell culture agriculture company GALY, was considering the best path forward for his company has he planned to pitch Series B investors. GALY, founded in 2019, aimed to produce cotton and other crops from cells grown in...
View Details
Keywords:
Business Model;
Green Technology;
Goods and Commodities;
Growth and Development Strategy;
Science-Based Business;
Entrepreneurship;
Plant-Based Agribusiness;
Business Startups;
Decisions;
Technological Innovation;
Production;
Agriculture and Agribusiness Industry;
Technology Industry;
Boston;
Sao Paulo
Serafeim, George, and Michael Norris. "Seeds of Innovation: GALY's Quest to Cultivate the Future of Agriculture in the Lab." Harvard Business School Case 124-017, September 2023. (Revised November 2023.)
- September 2023
- Teaching Note
Nexleaf Analytics: Saving the World Using the Internet of Things
By: Frank Nagle
Teaching Note for HBS Case 722-414.
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- September 2023 (Revised December 2023)
- Case
Viceroy Research versus Medical Properties Trust
By: Jonas Heese, Joseph Pacelli, Emilie Billaud and Carlota Moniz
Heese, Jonas, Joseph Pacelli, Emilie Billaud, and Carlota Moniz. "Viceroy Research versus Medical Properties Trust." Harvard Business School Case 124-027, September 2023. (Revised December 2023.)
- Fall 2023
- Article
Infringing Use as a Path to Legal Consumption: Evidence from a Field Experiment
By: Hong Luo and Julie Holland Mortimer
Digitization has transformed how users find and use copyrighted goods, but many existing legal options remain difficult to access, possibly leading to infringement. In a field experiment, we contact firms that are caught infringing on expensive digital images. Emails...
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Luo, Hong, and Julie Holland Mortimer. "Infringing Use as a Path to Legal Consumption: Evidence from a Field Experiment." Special Issue on Field Experiments edited by Michael Luca and Sarah Moshary. Journal of Economics & Management Strategy 32, no. 3 (Fall 2023): 523–542.
- August 2023 (Revised February 2024)
- Case
DexAI
By: Jo Tango and Christina Wallace
During a challenging fundraising environment, the DexAI founders received two term sheets with nearly identical economic terms but very different legal ones. The entrepreneurs had to navigate: representations and warranties (their personal guarantees that the company's...
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- 2023
- Working Paper
The Imperfect Intermediation of Money-Like Assets
By: Jonathan Wallen and Jeremy C. Stein
We study supply-and-demand effects in the U.S. Treasury bill market by comparing the returns on T-bills to the administered policy rate on the Federal Reserve’s reverse repurchase (RRP) facility. In spite of the arguably more money-like properties of an investment in...
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Wallen, Jonathan, and Jeremy C. Stein. "The Imperfect Intermediation of Money-Like Assets." Working Paper, August 2023.
- July 2023 (Revised December 2023)
- Case
Miracle Therapeutics (A): Negotiating an IP License
By: Satish Tadikonda, Michael Singer, William Marks and Wendi Yajnik
(General Experience Case) Beth Sharp and Jennifer Brilliant founded Miracle Therapeutics based on intellectual property developed by Brilliant and her post-doctoral student, John Supreme, in Brilliant’s lab at Elite University (EU). Miracle will have to obtain a...
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Tadikonda, Satish, Michael Singer, William Marks, and Wendi Yajnik. "Miracle Therapeutics (A): Negotiating an IP License." Harvard Business School Case 824-020, July 2023. (Revised December 2023.)
- 2023
- Working Paper
Algorithm Failures and Consumers' Response: Evidence from Zillow
By: Isamar Troncoso, Runshan Fu, Nikhil Malik and Davide Proserpio
In November 2021, Zillow announced the closure of its iBuyer business. Popular media largely attributed this to a failure of its proprietary forecasting algorithm. We study the response of consumers to Zillow’s iBuyer business closure. We show that after the iBuyer...
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Keywords:
Algorithmic Pricing;
Price;
Forecasting and Prediction;
Consumer Behavior;
Real Estate Industry
Troncoso, Isamar, Runshan Fu, Nikhil Malik, and Davide Proserpio. "Algorithm Failures and Consumers' Response: Evidence from Zillow." Working Paper, July 2023.
- July 2023
- Article
Design and Analysis of Switchback Experiments
By: Iavor I Bojinov, David Simchi-Levi and Jinglong Zhao
In switchback experiments, a firm sequentially exposes an experimental unit to a random treatment, measures its response, and repeats the procedure for several periods to determine which treatment leads to the best outcome. Although practitioners have widely adopted...
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Bojinov, Iavor I., David Simchi-Levi, and Jinglong Zhao. "Design and Analysis of Switchback Experiments." Management Science 69, no. 7 (July 2023): 3759–3777.