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      Pharmaceutical Industry Remove Pharmaceutical Industry →

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      • Article

      Variety of Innovation in Global Value Chains

      By: Giulio Buciuni and Gary P. Pisano
      This article analyzes how the geography and organization of pre- and production stages in Global Value Chains (GVC) contribute to lead firms' innovation development. A novel approach in GVC studies is introduced based on transaction cost economics (TCE) and the...  View Details
      Keywords: Gvc; Global Value Chains; Manufacturing; Production; Global Range; Innovation And Invention
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      Buciuni, Giulio, and Gary P. Pisano. "Variety of Innovation in Global Value Chains." Art. 101167. Journal of World Business 56, no. 2 (February 2021).
      • January 2021
      • Case

      Takeda Pharmaceutical Company Limited (A)

      By: David J. Collis, Nobuo Sato and Akiko Kanno
      This case follows Christophe Weber, President and CEO of Takeda Pharmaceutical Company Limited, a leading pharmaceutical company headquartered in Tokyo, Japan, as Takeda considers acquiring Shire Plc, a biotech company based in Ireland. The acquisition would turn...  View Details
      Keywords: Pharmaceutical Companies; Pharmaceutical Industry; Pharmaceuticals; Japan; Biotech; Biotechnology; M&a; Mergers & Acquisitions; Globalization; Management; Asia; R&d; Talent Management; Mergers And Acquisitions; Globalization; Global Strategy; pharmaceutical industry; Biotechnology industry; Japan
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      Collis, David J., Nobuo Sato, and Akiko Kanno. "Takeda Pharmaceutical Company Limited (A)." Harvard Business School Case 721-373, January 2021.
      • January 2021
      • Supplement

      Takeda Pharmaceutical Company Limited (B)

      By: David J. Collis, Nobuo Sato and Akiko Kanno
      This case is a follow up to HBS Case No. 721-373, Takeda Pharmaceutical Company Limited (A). Following the events of the previous case, Takeda reached an agreement to acquire Ireland-based Shire Plc. The case follows some of the achievements and challenges Takeda and...  View Details
      Keywords: Pharmaceutical Companies; Pharmaceutical Industry; Pharmaceuticals; M&a; Mergers & Acquisitions; Globalization; Japan; Biotech; Biotechnology; R&d; Talent Management; Asia; Strategy; Mergers And Acquisitions; Global Strategy; Strategy; Biotechnology industry; pharmaceutical industry; Japan
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      Collis, David J., Nobuo Sato, and Akiko Kanno. "Takeda Pharmaceutical Company Limited (B)." Harvard Business School Supplement 721-374, January 2021.
      • January 2021
      • Case

      Hester Pharmaceuticals (A): A Pricing Dilemma

      By: Dante Roscini and John Masko
      In August 2019, the leadership of Hester Pharmaceuticals (Hester) had a problem. Italy promised to be a key market for their new breakthrough oncology drug Akrozumab, but for almost two years, its single-payer healthcare system had been unable to agree with Hester on a...  View Details
      Keywords: Macroeconomics; Trade; Price; Global Range; Global Strategy; Globalized Markets And industries; Health Care And Treatment; Patents; Monopoly; Negotiation; Business And Government Relations; Risk And Uncertainty; Human Needs; Business Strategy; Commercialization; pharmaceutical industry; Italy
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      Roscini, Dante, and John Masko. "Hester Pharmaceuticals (A): A Pricing Dilemma." Harvard Business School Case 721-001, January 2021.
      • November 2020
      • Teaching Note

      Valuing Celgene's CVR

      By: Benjamin C. Esty and Daniel Fisher
      When Bristol-Myers Squibb (BMS) acquired Celgene Corporation in November 2019, Celgene shareholders received cash, BMS stock, and a contingent value right (CVRs) that would pay $9 if the U.S. Food and Drug Administration (FDA) approved three of Celgene’s late stage...  View Details
      Keywords: Mergers And Acquisitions; Valuation; Value; Judgments; Decision Making; Cash Flow; Financial Instruments; Cognition And Thinking; pharmaceutical industry; Biotechnology industry; United States
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      Esty, Benjamin C., and Daniel Fisher. "Valuing Celgene's CVR." Harvard Business School Teaching Note 221-036, November 2020.
      • November 2020
      • Case

      Valuing Celgene's CVR

      By: Benjamin C. Esty and Daniel Fisher
      When Bristol-Myers Squibb (BMS) acquired Celgene Corporation in November 2019, Celgene shareholders received cash, BMS stock, and a contingent value right (CVRs) that would pay $9 if the U.S. Food and Drug Administration (FDA) approved three of Celgene’s late stage...  View Details
      Keywords: Mergers And Acquisitions; Value; Valuation; Judgments; Decision Making; Cash Flow; Financial Instruments; Cognition And Thinking; pharmaceutical industry; Biotechnology industry; United States
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      Esty, Benjamin C., and Daniel Fisher. "Valuing Celgene's CVR." Harvard Business School Case 221-031, November 2020.
      • November 2020
      • Supplement

      Valuing Celgene's CVR

      By: Benjamin C. Esty and Daniel Fisher
      When Bristol-Myers Squibb (BMS) acquired Celgene Corporation in November 2019, Celgene shareholders received cash, BMS stock, and a contingent value right (CVRs) that would pay $9 if the U.S. Food and Drug Administration (FDA) approved three of Celgene’s late stage...  View Details
      Keywords: Mergers And Acquisitions; Value; Valuation; Judgments; Decision Making; Cash Flow; Financial Instruments; Cognition And Thinking; pharmaceutical industry; Biotechnology industry; United States
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      Esty, Benjamin C., and Daniel Fisher. "Valuing Celgene's CVR." Harvard Business School Spreadsheet Supplement 221-705, November 2020.
      • October 2020
      • Teaching Plan

      Merck: COVID-19 Vaccines

      By: Willy C. Shih
      COVID-19 infections were still climbing across the U.S. and many other parts of the world in September 2020, and it seemed that every time Ken Frazier, the CEO of Merck & Co. consented to an interview in recent months he always seemed to hear the same question,...  View Details
      Keywords: Vaccines; Health Pandemics; Health Testing And Trials; Innovation And Management; Innovation Strategy; Research And Development; Business Strategy; pharmaceutical industry; United States
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      Shih, Willy C. "Merck: COVID-19 Vaccines." Harvard Business School Teaching Plan 621-067, October 2020.
      • October 2020
      • Case

      When Institutions Fail: HIV/AIDS in the 1980s

      By: Tom Nicholas and Christian Godwin
      During the early 1980s, young gay men in urban centers such as San Francisco and New York City began contracting a mysterious illness that would come to be known as HIV/AIDS. A diagnosis meant almost certain death, with a less than 1% survival rate. Conflicting...  View Details
      Keywords: Ethics; Policy; Government And Politics; Health; History; Rights; Media; Organizations; Business And Community Relations; Religion; Social Psychology; Identity; Prejudice And Bias; Social Issues; Public Opinion; pharmaceutical industry; Biotechnology industry; Health industry; Journalism And News industry; Media And Broadcasting industry; Public Administration industry; United States
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      Nicholas, Tom, and Christian Godwin. "When Institutions Fail: HIV/AIDS in the 1980s." Harvard Business School Case 821-002, October 2020.
      • September 2020
      • Case

      Merck: COVID-19 Vaccines

      By: Willy C. Shih
      COVID-19 infections were still climbing across the U.S. and many other parts of the world in September 2020, and it seemed that every time Ken Frazier, the CEO of Merck & Co. consented to an interview in recent months he always seemed to hear the same question,...  View Details
      Keywords: Vaccines; Health Pandemics; Health Testing And Trials; Innovation And Management; Innovation Strategy; Technological Innovation; Business Strategy; pharmaceutical industry
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      Shih, Willy C. "Merck: COVID-19 Vaccines." Harvard Business School Case 621-028, September 2020.
      • September 2020 (Revised January 2021)
      • Case

      Catalys Pacific

      By: Joshua Lev Krieger
      In 2019, BT Slingsby founds Catalys Pacific, the first biotech “venture creation” fund in Tokyo. After convincing some of the biggest Japanese pharmaceutical firms to invest, BT hopes the fund can make a big splash and transform biotechnology innovation in Japan. After...  View Details
      Keywords: Pharmaceutical Companies; Biotech; Health Care; Entrepreneur; Innovation; International Business; Entrepreneurial Finance; Entrepreneurship; Finance; Innovation Strategy; Venture Capital; Strategy; Cross-cultural And Cross-border Issues; pharmaceutical industry; Biotechnology industry; Tokyo
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      Krieger, Joshua Lev. "Catalys Pacific." Harvard Business School Case 821-035, September 2020. (Revised January 2021.)
      • September–October 2020
      • Article

      Social-Impact Efforts That Create Real Value

      By: George Serafeim
      Until the mid-2010s few investors paid attention to environmental, social, and governance (ESG) data—information about companies’ carbon footprints, labor policies, board makeup, and so forth. Today the data is widely used by investors. How can organizations create...  View Details
      Keywords: Sustainability; Sustainability Management; Esg; Esg (environmental, Social, Governance) Performance; Esg (environmental, Social, Governance) Performance; Esg Disclosure; Esg Disclosure Metrics; Esg Ratings; Esg Reporting; Social Impact; Impact Measurement; Social Innovation; Purpose; Corporate Purpose; Corporate Social Responsibility; Strategy; Social Enterprise; Society; Accounting; Investment; Environmental Sustainability; Climate Change; Corporate Strategy; Mission And Purpose; Corporate Social Responsibility And Impact; Financial Services industry; Chemical industry; Technology industry; Consumer Products industry; pharmaceutical industry; North America; Europe; Japan; Australia
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      Serafeim, George. "Social-Impact Efforts That Create Real Value." Harvard Business Review 98, no. 5 (September–October 2020): 38–48.
      • June 2020
      • Case

      Breakthroughs at Blueprint Medicines

      By: Richard G. Hamermesh, Kathy Giusti and Susie L. Ma
      Precision medicine company Blueprint Medicines was building a successful track record for bringing drug therapies to market 40% faster than average. The company had spent $40 million dollars and two years building a compound library that became its drug development...  View Details
      Keywords: Precision Medicine; Cancer; Biotechnology; Drug Development; Strategy; Expansion; Science; Genetics; Technology; Entrepreneurship; Organizational Culture; Management; Growth And Development; pharmaceutical industry; United States; Cambridge; Massachusetts
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      Hamermesh, Richard G., Kathy Giusti, and Susie L. Ma. "Breakthroughs at Blueprint Medicines." Harvard Business School Case 820-001, June 2020.
      • May 2020 (Revised June 2020)
      • Case

      The Coronavirus (COVID-19) Pandemic and the Global Economy (A)

      By: Alberto Cavallo and Christian Godwin
      In April 2020, the world struggled to contain the exponential escalation of the coronavirus (COVID-19) pandemic. Dozens of countries had imposed restrictions on travel, work, and social gatherings. A large share of the global population was under lockdowns and...  View Details
      Keywords: Demand And Consumers; Supply And industry; Finance; Central Banking; Financial Markets; International Finance; Globalization; Government And Politics; Health Pandemics; Decision Making; Macroeconomics; Employment; Crisis Management; Supply Chain; Risk And Uncertainty; Air Transportation industry; Banking industry; Consumer Products industry; Employment industry; Financial Services industry; Food And Beverage industry; Health industry; Medical Devices And Supplies industry; pharmaceutical industry; Public Administration industry; Retail industry; Service industry; Shipping industry; Tourism industry; Travel industry; Asia; China; Europe; Latin America; Africa; United States
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      Cavallo, Alberto, and Christian Godwin. "The Coronavirus (COVID-19) Pandemic and the Global Economy (A)." Harvard Business School Case 720-031, May 2020. (Revised June 2020.)
      • Working Paper

      Rebates in the Pharmaceutical Industry: Evidence from Medicines Sold in Retail Pharmacies in the U.S.

      By: Pragya Kakani, Michael Chernew and Amitabh Chandra
      Rising list prices are often used to illustrate the burden of prescription drug spending, but payers routinely negotiate rebates from manufacturers that generate differences between list and net prices. List prices are easily available and affect patient cost-sharing,...  View Details
      Keywords: Pharmaceuticals; Rebates; Health Care And Treatment; Markets; Price; Analysis; pharmaceutical industry
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      Kakani, Pragya, Michael Chernew, and Amitabh Chandra. "Rebates in the Pharmaceutical Industry: Evidence from Medicines Sold in Retail Pharmacies in the U.S." NBER Working Paper Series, No. 26846, March 2020.
      • January 2020
      • Case

      Celata Bioinnovations

      By: John R. Wells and Benjamin Weinstock
      In December 2019, Jon Hu (HBS ‘19) and Dr. Samantha Dale Strasser, co-founders of Celata Bioinnovations, were raising $1 million to launch their company. They had founded Celata less than six months earlier with the aim of redefining the drug discovery process....  View Details
      Keywords: Drug Development; Drug Discovery; Drug Trials; Pharmaceutical Companies; Pharmaceutical Company; Pharmaceuticals; Therapeutics; Biologics; Biotech; Biotechnology; Biopharmacy Company; Biochemistry; Technology Commercialization; Technology Companies; Drug Testing; Startup; Start-up; Startups; Start-ups; Startup Financing; Strategic Decision Making; Strategic Decisions; Strategic Evolution; Fda; Food And Drug Administration; Clinical Trials; Disease Management; Market Attractiveness; Market Entry; Market Opportunities; Health Disorders; Technological Innovation; Technology; Commercialization; Business Startups; Finance; Decision Making; Strategy; Market Entry And Exit; Opportunities; pharmaceutical industry; Biotechnology industry
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      Wells, John R., and Benjamin Weinstock. "Celata Bioinnovations." Harvard Business School Case 720-427, January 2020.
      • 2020
      • Book

      Fit to Compete: Why Honest Conversations About Your Company's Capabilities Are the Key to a Winning Strategy

      By: Michael Beer
      Is Silence Killing Your Strategy?
      In his thirty years of working in corporations, Harvard Business School professor Michael Beer has witnessed firsthand how organizational silence derails strategic objectives. When employees can't speak truth to power, senior...  View Details
      Keywords: Honesty; Communication; Organizational Culture; Trust; Strategy; Performance Effectiveness
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      Beer, Michael. Fit to Compete: Why Honest Conversations About Your Company's Capabilities Are the Key to a Winning Strategy. Boston: Harvard Business Review Press, 2020.
      • December 2019
      • Case

      The Business of Pain: Johnson & Johnson and the Promise of Opioids

      By: Erik Snowberg, Trevor Fetter and Amy W. Schulman
      This case is designed to provide an engrossing overview of stakeholder capitalism through a vigorous discussion of the conflicts that can arise when trying to serve multiple stakeholders. In 2007, Johnson & Johnson’s (J&J) subsidiary Janssen has to decide whether or...  View Details
      Keywords: Opioids; Addiction; Stakeholder Capitalism; Business And Stakeholder Relations; Product Launch; Decision Making; Ethics; Social Issues; pharmaceutical industry
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      Snowberg, Erik, Trevor Fetter, and Amy W. Schulman. "The Business of Pain: Johnson & Johnson and the Promise of Opioids." Harvard Business School Case 720-420, December 2019.
      • December 2019
      • Supplement

      The Business of Pain: Johnson & Johnson and the Promise of Opioids (B)

      By: Erik Snowberg, Trevor Fetter and Amy W. Schulman
      This case is designed to provide an engrossing overview of stakeholder capitalism through a vigorous discussion of the conflicts that can arise when trying to serve multiple stakeholders. In 2007, Johnson & Johnson’s (J&J) subsidiary Janssen has to decide whether or...  View Details
      Keywords: Opioids; Addiction; Business And Stakeholder Relations; Product Launch; Ethics; Society; pharmaceutical industry
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      Snowberg, Erik, Trevor Fetter, and Amy W. Schulman. "The Business of Pain: Johnson & Johnson and the Promise of Opioids (B)." Harvard Business School Supplement 720-423, December 2019.
      • December 2019
      • Case

      Bill & Melinda Gates Foundation: Shaping the Vaccine Manufacturing Ecosystem (Abridged)

      By: Willy Shih
      This case describes the efforts of the Bill & Melinda Gates Foundation to lower the cost of producing vaccines to prevent polio infections. It is an abridged version of HBS Case No. 620-021 with less emphasis on comparison between traditional and the new compact...  View Details
      Keywords: Vaccine; Manufacturing; Barriers To Entry; Production; Cost; Technological Innovation; Market Entry And Exit; pharmaceutical industry
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      Shih, Willy. "Bill & Melinda Gates Foundation: Shaping the Vaccine Manufacturing Ecosystem (Abridged)." Harvard Business School Case 620-071, December 2019.
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