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- September 2021
- Supplement
Hester Pharmaceuticals (B): Securing Supply
By: Dante Roscini and John Masko
In 2020, amid the COVID-19 pandemic and a rise in “reshoring” sentiment in the U.S., Hester Pharmaceuticals had to decide whether to build a new plant for its new oncology drug Akrozumab in Germany or in the U.S., or whether it should hire a contract manufacturing...
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- August 2021
- Teaching Note
Coats: Supply Chain Challenges
By: Willy C. Shih
Teaching Note for HBS Case No. 621-115.
Faced with continuing cost pressure, should Coats, the world's largest thread maker, relocate some of its make-to-stock manufacturing to an ultra-low-cost region while leaving make-to-order demand close to customers?
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- Summer 2021
- Article
The Cost and Evolution of Quality at Cipla Ltd, 1935–2016
By: Muhammad H. Zaman and Tarun Khanna
This article examines the evolution of Indian pharmaceutical manufacturer Cipla towards producing drugs that met the quality standards of European and U.S. regulators. It employs new research in Cipla’s corporate archives, the Creating Emerging Markets database, and...
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- February 2021
- Case
Digital Manufacturing at Amgen
By: Shane Greenstein, Kyle Myers and Sarah Mehta
This case discusses efforts made by biotechnology (biotech) company Amgen to introduce digital technologies into its manufacturing processes. Doing so is complicated by the fact that the process for manufacturing biologics—or therapeutics made from living cells—is...
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Keywords:
Digital Technologies;
Change;
Change Management;
Decision Making;
Cost vs Benefits;
Decisions;
Information;
Data and Data Sets;
Innovation and Invention;
Innovation and Management;
Innovation Leadership;
Innovation Strategy;
Technological Innovation;
Jobs and Positions;
Knowledge;
Leadership;
Organizational Culture;
Science;
Strategy;
Technology;
Technology Adoption;
Biotechnology Industry;
Pharmaceutical Industry;
United States;
California;
Puerto Rico;
Rhode Island
- Article
Variety of Innovation in Global Value Chains
By: Giulio Buciuni and Gary P. Pisano
This article analyzes how the geography and organization of pre- and production stages in Global Value Chains (GVC) contribute to lead firms' innovation development. A novel approach in GVC studies is introduced based on transaction cost economics (TCE) and the...
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- September 2020
- Teaching Note
TransDigm in 2017: The Beginning of the End or the End of the Beginning?
By: Benjamin C. Esty and Daniel Fisher
Teaching Note for HBS Case No. 720-422. TransDigm was a highly acquisitive company that manufactured a wide range of highly engineered aerospace parts for both military and commercial customers. Over the ten years ending in 2016, its stock price had increase ten times,...
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Keywords:
Value Capturing;
Pricing Strategy;
Supplier Power;
Buyer Power;
Porter's Five Forces;
Bargaining Power;
Monopoly;
Aerospace;
Acquisition Strategy;
Value Drivers;
Ethical Behavior;
Regulation;
Growth Strategy;
Business Ethics;
Defense;
Procurement;
Sustainability;
Value-Based Business Strategy;
Acquisition;
Ethics;
Private Equity;
Financial Strategy;
Growth Management;
Performance Evaluation;
Business Strategy;
Competitive Strategy;
Horizontal Integration;
Value Creation;
Competitive Advantage;
Aerospace Industry;
Air Transportation Industry;
United States
- July 2020
- Article
Lessons from the Impact of Price Regulation on the Pricing of Anticancer Drugs in Germany
By: Victoria D. Lauenroth, Aaron S. Kesselheim, Ameet Sarpatwari and Ariel Dora Stern
Worldwide spending on prescription drugs has increased dramatically in recent years. Although this increase has been particularly pronounced in the U.S., it remains largely unaddressed there. In Europe, however, different approaches to regulating drug prices have been...
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- May 2020 (Revised June 2020)
- Case
TransDigm's Acquisition and Integration of Arkwin Industries
By: Benjamin C. Esty and Daniel W. Fisher
In May 2013, TransDigm, a company that manufactured a wide range of highly engineered aerospace parts for both military and civilian aircraft, announced it was buying Arkwin Industries for $286 million in cash (3 times Arkwin’s sales of $91 million). Having acquired...
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- April 2020 (Revised July 2020)
- Supplement
TransDigm in 2017: The Beginning of the End or the End of the Beginning?
By: Benjamin C. Esty and Daniel Fisher
TransDigm was a highly acquisitive company that manufactured a wide range of highly engineered aerospace parts for both military and commercial customers. Over the ten years ending in 2016, its stock price had increase ten times, and both EBITDA and revenues had grown...
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- April 2020 (Revised July 2020)
- Case
TransDigm in 2017: The Beginning of the End or the End of the Beginning?
By: Benjamin C. Esty and Daniel Fisher
TransDigm was a highly acquisitive company that manufactured a wide range of highly engineered aerospace parts for both military and commercial customers. Over the ten years ending in 2016, its stock price had increased ten times, and both EBITDA and revenues had grown...
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Keywords:
Value Capturing;
Pricing Strategy;
Supplier Power;
Buyer Power;
Porter's Five Forces;
Bargaining Power;
Monopoly;
Aerospace;
Acquisition Strategy;
Value Drivers;
Ethical Behavior;
Regulation;
Growth Strategy;
Business Ethics;
Defense;
Procurement;
Sustainability;
Value-Based Business Strategy;
Acquisition;
Ethics;
Private Equity;
Financial Strategy;
Growth Management;
Performance Evaluation;
Business Strategy;
Competitive Strategy;
Horizontal Integration;
Value Creation;
Competitive Advantage;
Aerospace Industry;
Air Transportation Industry;
United States
- 2021
- Working Paper
Local Shocks and Internal Migration: The Disparate Effects of Robots and Chinese Imports in the U.S.
By: Marius Faber, Andres Sarto and Marco Tabellini
Migration has long been considered one of the key mechanisms through which labor markets adjust to economic shocks. In this paper, we analyze the migration response of American workers to two of the most important shocks that hit US manufacturing since the late 1990s —...
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- December 2019
- Case
Bill & Melinda Gates Foundation: Shaping the Vaccine Manufacturing Ecosystem (Abridged)
By: Willy Shih
This case describes the efforts of the Bill & Melinda Gates Foundation to lower the cost of producing vaccines to prevent polio infections. It is an abridged version of HBS Case No. 620-021 with less emphasis on comparison between traditional and the new compact...
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- November 2019
- Case
Celebrity Fashions Limited (A)
By: V.G. Narayanan, Tanvi Deshpande and Shreya Ramachandran
In May 2017 in Chennai, India, the chairman of Celebrity Fashions doubted whether the company could last until the end of the year. Venkatesh Rajagopal had found that the company, a readymade garment manufacturing and exporter he founded in 1989, was having a hard time...
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- October 2019
- Supplement
Airbus vs. Boeing (L): Discontinuing the A380 (February 2019)
By: Ramon Casadesus-Masanell and Karen Elterman
This case describes Airbus’ February 2019 announcement that it was ending production of the A380, with the last delivery scheduled for 2021. The announcement followed an order cancellation by Emirates, a major customer of the A380. The A380 had faced significant...
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- September 2019
- Case
Bill & Melinda Gates Foundation: Shaping the Vaccine Manufacturing Ecosystem
By: Willy C. Shih
Vaccines for children has been a long-standing focus for the Bill & Melinda Gates Foundation, and its critical role in public health made its production an important economic and political issue. This case describes the Foundation's investment in a breakthrough vaccine...
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- September 2019
- Case
Teaming Up to Win the Rail Deal at GE (A)
By: Amy Edmondson, Ranjay Gulati and Rachna Tahilyani
In 2012, Nalin Jain, then head of GE aviation for South Asia, was given the added responsibility for GE’s transportation business in India, including bidding for a $2.5 billion contract to manufacture, service and maintain 1,000 diesel locomotives for state owned...
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- April 2019
- Case
Barber Cardiosystems
By: Ranjay Gulati and Paul S. Myers
Barber Cardiosystems, based in Melbourne, Australia, designs and manufactures therapeutic devices used for treatment of coronary conditions. Over four decades, it has grown to be among the top 200 medical device companies in the world. It competes against much larger...
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- April 2019 (Revised April 2021)
- Case
Wayfair
By: Jeffrey F. Rayport, Susie L. Ma and Matthew G. Preble
In 2016 Niraj Shah and Steve Conine, founders of online home goods retailer Wayfair, are faced with a decision about how to improve user experience on their e-commerce sites. A key driver of consumer interest and conversion to purchase in the home category is visual...
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- December 2018
- Case
Choosy
By: Jeffrey J. Bussgang and Julia Kelley
Founded in 2017, Choosy is a data-driven fashion startup that uses algorithms to identify styles trending on social media. After manufacturing similar items using a China-based supply chain, Choosy sells them to consumers through its website and social media pages....
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Keywords:
Artificial Intelligence;
Algorithms;
Machine Learning;
Neural Networks;
Instagram;
Social Media;
Influencer;
Fast Fashion;
Design;
Customer Satisfaction;
Customer Focus and Relationships;
Decision Making;
Cost vs Benefits;
Innovation and Invention;
Brands and Branding;
Product Positioning;
Demand and Consumers;
Supply Chain;
Production;
Logistics;
Business Model;
Expansion;
Internet;
Mobile Technology;
Online Technology;
Technology Platform;
Technology Industry;
Fashion Industry;
North and Central America;
United States;
New York (state, US);
New York (city, NY)
- November 2018 (Revised June 2019)
- Case
ofo
By: Mitchell Weiss
Dai Wei and his co-founders grew Beijing-based ofo from a school-based startup to a bike-share behemoth in a matter of months, topped an all-out market-share battle fueled with almost $1 billion in venture capital, provided 2 billion bicycle rides, soaked up the...
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Keywords:
Ofo;
Bikeshare;
Scale;
Platforms;
Government As A Platform;
Platform Mechanics;
Dai Wei;
Dockless Bikes;
Mobike;
Bike-share;
Online-to-offline;
Mobility;
Market Platforms;
One-Sided Platforms;
Infrastructure;
Transportation;
Bicycle Transportation;
Growth and Development Strategy;
Bicycle Industry;
China;
Beijing