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- Faculty Publications (178)
- 2022
- Working Paper
Post-market Surveillance of Software Medical Devices: Evidence from Regulatory Data
By: Alexander O. Everhart and Ariel D. Stern
Medical devices increasingly include software components, which facilitate remote patient monitoring. The introduction of software into previously analog medical devices as well as innovation in software-driven devices may introduce new safety concerns—all the more so...
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Keywords:
Technological Innovation;
Safety;
Governing Rules, Regulations, and Reforms;
Health Care and Treatment;
Medical Devices and Supplies Industry
Everhart, Alexander O., and Ariel D. Stern. "Post-market Surveillance of Software Medical Devices: Evidence from Regulatory Data." Harvard Business School Working Paper, No. 23-035, November 2022.
- December 2022
- Article
Social Skills Improve Business Performance: Evidence from a Randomized Control Trial with Entrepreneurs in Togo
By: Stefan Dimitriadis and Rembrand Koning
Recent field experiments demonstrate that advice, mentorship, and feedback from randomly assigned peers improve entrepreneurial performance. These results raise a natural question: what is preventing entrepreneurs and managers from forming these peer connections...
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Keywords:
Social Skills;
Business Performance;
Entrepreneurs;
Peer Relationships;
Field Experiment;
Entrepreneurship;
Performance;
Relationships;
Interpersonal Communication;
Togo
Dimitriadis, Stefan, and Rembrand Koning. "Social Skills Improve Business Performance: Evidence from a Randomized Control Trial with Entrepreneurs in Togo." Management Science 68, no. 12 (December 2022): 8635–8657.
- September 2022
- Article
Health Externalities and Policy: The Role of Social Preferences
By: Laura Alfaro, Ester Faia, Nora Lamersdorf and Farzad Saidi
Social preferences facilitate the internalization of health externalities, for example by reducing mobility during a pandemic. We test this hypothesis using mobility data from 258 cities worldwide alongside experimentally validated measures of social preferences....
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Keywords:
Social Preferences;
Pandemics;
Mobility;
Health Externalities;
Mitigation Policies;
Health Pandemics;
Cooperation;
Behavior;
Policy
Alfaro, Laura, Ester Faia, Nora Lamersdorf, and Farzad Saidi. "Health Externalities and Policy: The Role of Social Preferences." Management Science 68, no. 9 (September 2022): 6751–6761.
- August 13, 2022
- Article
A Historic Opportunity for Universal Health Coverage in India
By: Vikram Patel, Shubhangi Bhadada, Kiran Mazumdar-Shaw, Arnab Mukherji, Tarun Khanna and Gagandeep Kang
The milestone of India's 75th anniversary of independence on Aug 15, 2022, offers an opportunity to reassert the country's commitment to realising universal health coverage (UHC). The first such effort predates independence, with the 1946 Bhore Committee report....
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Keywords:
Universal Health Coverage;
COVID-19 Pandemic;
Health Care and Treatment;
Gender;
Prejudice and Bias;
Health Industry;
India
Patel, Vikram, Shubhangi Bhadada, Kiran Mazumdar-Shaw, Arnab Mukherji, Tarun Khanna, and Gagandeep Kang. "A Historic Opportunity for Universal Health Coverage in India." Lancet 400, no. 10351 (August 13, 2022): 475–477.
- August 2022 (Revised August 2023)
- Case
NOW PT (A): Should We Invest?
By: George A Riedel, Amy Klopfenstein and Mel Martin
In fall 2021, a team of students from the HBS Impact Investing Fund considered Neurologic Optimal Wellness Physical Therapy (NOW PT) for a potential investment. Dr. Banks, the founder of NOW PT, drove to visit patients. She sought an investment from the fund to open a...
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Keywords:
Entrepreneurship;
Social Entrepreneurship;
Finance;
Investment;
Health;
Health Care and Treatment;
Medical Specialties;
Buildings and Facilities;
Health Industry;
Health Industry;
North and Central America;
United States;
Massachusetts
Riedel, George A., Amy Klopfenstein, and Mel Martin. "NOW PT (A): Should We Invest?" Harvard Business School Case 323-009, August 2022. (Revised August 2023.)
- August 2022
- Case
Rocket Learning: Evidence in Action
By: Brian Trelstad, Tomas Rosales and Malini Sen
Founders of Rocket Learning, an India-based nonprofit which focused on early childhood education (ECE), received an invitation from MIT’s Abdul Latif Jameel Poverty Action Lab (JPAL), a development research organization, to test its intervention for ECE with a...
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Keywords:
Social Entrepreneurship;
Early Childhood Education;
Nonprofit Organizations;
Literacy;
Values and Beliefs;
Social and Collaborative Networks;
Education Industry;
India;
Asia
Trelstad, Brian, Tomas Rosales, and Malini Sen. "Rocket Learning: Evidence in Action." Harvard Business School Case 323-002, August 2022.
- 2022
- Working Paper
Causal Inference During A Pandemic: Evidence on the Effectiveness of Nebulized Ibuprofen as an Unproven Treatment for COVID-19 in Argentina
By: Sebastian Calonico, Rafael Di Tella and Juan Cruz Lopez Del Valle
Many medical decisions during the pandemic were made without the support of causal evidence obtained in clinical trials. We study the case of nebulized ibuprofen (NaIHS), a drug that was extensively used on COVID-19 patients in Argentina amidst wild claims about its...
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Keywords:
COVID-19;
Drug Treatment;
Health Pandemics;
Health Care and Treatment;
Decision Making;
Outcome or Result;
Argentina
Calonico, Sebastian, Rafael Di Tella, and Juan Cruz Lopez Del Valle. "Causal Inference During A Pandemic: Evidence on the Effectiveness of Nebulized Ibuprofen as an Unproven Treatment for COVID-19 in Argentina." NBER Working Paper Series, No. 30084, May 2022.
- April 2022
- Teaching Note
CVS Health: Prescription for Transformation
By: Rosabeth Moss Kanter and Catarina Martinez
In 2021, new CEO Karen Lynch (named the most powerful woman in business) considered the next transformation phase for CVS Health (a Fortune 5 corporate giant). The 2018 acquisition of Aetna insurance brought her to the company as part of its long evolution from a...
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- February 2022 (Revised April 2022)
- Case
CVS Health: Prescription for Transformation
By: Rosabeth Moss Kanter and Tuna Cem Hayirli
In 2021, new CEO Karen Lynch (named the most powerful woman in business) considered the next transformation phase for CVS Health (a Fortune 5 corporate giant. The 2018 acquisition of Aetna insurance brought her to the company as part of its long evolution from a...
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Keywords:
COVID;
Caregiving;
Healthcare;
Access;
Change;
Retail;
Health;
Health Care and Treatment;
Organizational Change and Adaptation;
Transformation;
Health Industry;
Health Industry
Kanter, Rosabeth Moss, and Tuna Cem Hayirli. "CVS Health: Prescription for Transformation." Harvard Business School Case 322-091, February 2022. (Revised April 2022.)
- February 2022
- Case
Leading The UK Vaccine Task Force
By: Amy C. Edmondson and Claudia Pienica
This case describes the first six months of the UK Vaccine Taskforce, under the leadership of Kate Bingham. With a career spent in the private sector as a biotech investor, Bingham’s appointment within the government was considered unusual. The overarching brief given...
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Keywords:
COVID-19;
Vaccine;
Government;
Health Pandemics;
Health Care and Treatment;
Science;
Innovation and Invention;
Groups and Teams;
Leadership;
Decision Making;
Government and Politics;
Health;
Innovation and Management;
Governance;
Change;
Government Administration;
Health Industry;
Health Industry;
Health Industry;
Europe;
United Kingdom
Edmondson, Amy C., and Claudia Pienica. "Leading The UK Vaccine Task Force." Harvard Business School Case 622-079, February 2022.
- February 15, 2022
- Article
How Managers Can Build a Culture of Experimentation
By: Frank V. Cespedes and Neil Hoyne
Testing in business presents qualitatively different challenges than those in clinical trials and most scientific research. There are very few opportunities for randomized control experiments in a changing, competitive market. Yet, change and competition make testing a...
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Cespedes, Frank V., and Neil Hoyne. "How Managers Can Build a Culture of Experimentation." Harvard Business Review Digital Articles (February 15, 2022).
- Article
A 680,000-Person Megastudy of Nudges to Encourage Vaccination in Pharmacies
By: Katherine L. Milkman, Linnea Gandhi, Mitesh S. Patel, Heather N. Graci, Dena M. Gromet, Hung Ho, Joseph S. Kay, Timothy W. Lee, Jake Rothschild, Jonathan E. Bogard, Ilana Brody, Christopher F. Chabris, Edward Chang, Gretchen B. Chapman, Jennifer E. Dannals, Noah J. Goldstein, Amir Goren, Hal Hershfield, Alex Hirsch, Jillian Hmurovic, Samantha Horn, Dean Karlan, Ariella S. Kristal, Cait Lamberton, Michael N. Meyer, Allison H. Oakes, Maurice E. Schweitzer, Maheen Shermohammed, Jaochim H. Talloen, Caleb Warren, Ashley V. Whillans, Kuldeep N. Yadav, Julian J. Zlatev, Ron Berman, Chalanda N. Evans, Rahul Ladhania, Jens Ludwig, Nina Mazar, Sendhil Mullainathan, Christopher K. Snider, Jann Spiess, Eli Tsukayama, Lyle Ungar, Christophe Van den Bulte, Kevin G. Volpp and Angela L. Duckworth
Encouraging vaccination is a pressing policy problem. To assess whether text-based reminders can encourage pharmacy vaccination and what kinds of messages work best, we conducted a megastudy. We randomly assigned 689,693 Walmart pharmacy patients to receive one of 22...
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Keywords:
Vaccination;
Vaccines;
Nudges;
Communication Strategy;
Communication Technology;
Consumer Behavior;
Health Care and Treatment
Milkman, Katherine L., Linnea Gandhi, Mitesh S. Patel, Heather N. Graci, Dena M. Gromet, Hung Ho, Joseph S. Kay, Timothy W. Lee, Jake Rothschild, Jonathan E. Bogard, Ilana Brody, Christopher F. Chabris, Edward Chang, Gretchen B. Chapman, Jennifer E. Dannals, Noah J. Goldstein, Amir Goren, Hal Hershfield, Alex Hirsch, Jillian Hmurovic, Samantha Horn, Dean Karlan, Ariella S. Kristal, Cait Lamberton, Michael N. Meyer, Allison H. Oakes, Maurice E. Schweitzer, Maheen Shermohammed, Jaochim H. Talloen, Caleb Warren, Ashley V. Whillans, Kuldeep N. Yadav, Julian J. Zlatev, Ron Berman, Chalanda N. Evans, Rahul Ladhania, Jens Ludwig, Nina Mazar, Sendhil Mullainathan, Christopher K. Snider, Jann Spiess, Eli Tsukayama, Lyle Ungar, Christophe Van den Bulte, Kevin G. Volpp, and Angela L. Duckworth. "A 680,000-Person Megastudy of Nudges to Encourage Vaccination in Pharmacies." e2115126119. Proceedings of the National Academy of Sciences 119, no. 6 (February 8, 2022).
- February 2022 (Revised November 2022)
- Case
Nuritas
By: Mitchell Weiss, Satish Tadikonda, Vincent Dessain and Emer Moloney
Nora Khaldi had built a technology “to unlock the power of nature” in the service of extending human lifespan and improving health, and now in April 2020 was debating telling her Board of Directors she wanted to put on ice some of her discoveries. Nuritas, the company...
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Keywords:
Cash Burn;
Cash Flow Analysis;
Pharmaceutical Companies;
Founder;
Artificial Intelligence;
AI;
Entrepreneurship;
Health Testing and Trials;
Health Care and Treatment;
Decision Making;
Market Entry and Exit;
AI and Machine Learning;
Pharmaceutical Industry
Weiss, Mitchell, Satish Tadikonda, Vincent Dessain, and Emer Moloney. "Nuritas." Harvard Business School Case 822-080, February 2022. (Revised November 2022.)
- January 17, 2022
- Article
Reducing Racial Disparities in Cancer Outcomes
By: Kathy Giusti and Richard G. Hamermesh
A disproportionate number of Black patients die from cancer in the United States. A key to addressing this problem is enrolling more Black patients in clinical trials. A strategy consisting of these three parts can help accomplish this goal: 1) centralize information...
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Giusti, Kathy, and Richard G. Hamermesh. "Reducing Racial Disparities in Cancer Outcomes." Harvard Business Review (website) (January 17, 2022).
- January 2022
- Article
Rational Habit Formation: Experimental Evidence from Handwashing in India
By: Reshmaan Hussam, Atonu Rabbani, Giovanni Reggiani and Natalia Rigol
We test the predictions of the rational addiction model, reconceptualized as rational habit formation, in the context of handwashing in rural India. To track handwashing, we design soap dispensers with timed sensors. We test for rational habit formation by informing...
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Hussam, Reshmaan, Atonu Rabbani, Giovanni Reggiani, and Natalia Rigol. "Rational Habit Formation: Experimental Evidence from Handwashing in India." American Economic Journal: Applied Economics 14, no. 1 (January 2022): 1–41. (Lead Article.)
- October 2021 (Revised January 2022)
- Supplement
Michael Ku and Global Clinical Supply at Pfizer Inc.: Bringing Hope to Patients (C)
By: Linda A. Hill and Emily Tedards
This case is the third installment in a series about the 10-year cultural and digital transformation of Pfizer’s Global Clinical Supply organization. In 2011, Michael Ku became Pfizer’s Vice President of Global Clinical Supply (GCS) after the company had undergone...
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Keywords:
Clinical Supply Chain;
COVID-19;
Vaccine;
Agile;
Innovation and Invention;
Change Management;
Organizational Culture;
Transformation;
Leadership;
Corporate Strategy;
Health Pandemics;
Crisis Management;
Mission and Purpose;
Health Care and Treatment;
Supply Chain Management;
Digital Transformation
Hill, Linda A., and Emily Tedards. "Michael Ku and Global Clinical Supply at Pfizer Inc.: Bringing Hope to Patients (C)." Harvard Business School Supplement 422-041, October 2021. (Revised January 2022.)
- September 2021
- Article
Perceptions on Undertaking Regular Asymptomatic Self-testing for COVID-19 Using Lateral Flow Tests: A Qualitative Study of University Students and Staff
By: Marta Wanat, Mary Logan, Jennifer A. Hirst, Charles Vicary, Joseph J. Lee, Rafael Perera, Irene Tracey, Gordon Duff, Peter Tufano, Thomas Fanshawe, Lazaro Mwandigha, Brian D. Nicholson, Sarah Tonkin-Crine and Richard Hobbs
Objectives: Successful implementation of asymptomatic testing programmes using lateral flow tests (LFTs) depends on several factors, including feasibility, acceptability and how people act on test results. We aimed to examine experiences of university students...
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Wanat, Marta, Mary Logan, Jennifer A. Hirst, Charles Vicary, Joseph J. Lee, Rafael Perera, Irene Tracey, Gordon Duff, Peter Tufano, Thomas Fanshawe, Lazaro Mwandigha, Brian D. Nicholson, Sarah Tonkin-Crine, and Richard Hobbs. "Perceptions on Undertaking Regular Asymptomatic Self-testing for COVID-19 Using Lateral Flow Tests: A Qualitative Study of University Students and Staff." BMJ Open 11, no. 9 (September 2021).
- Article
Measuring the Scientific Effectiveness of Contact Tracing: Evidence from a Natural Experiment
By: Thiemo Fetzer and Thomas Graeber
Contact tracing has for decades been a cornerstone of the public health approach to epidemics, including Ebola, severe acute respiratory syndrome, and now COVID-19. It has not yet been possible, however, to causally assess the method’s effectiveness using a randomized...
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Fetzer, Thiemo, and Thomas Graeber. "Measuring the Scientific Effectiveness of Contact Tracing: Evidence from a Natural Experiment." Proceedings of the National Academy of Sciences 118, no. 33 (August 17, 2021): 1–4.
- Article
A Multi-country Test of Brief Reappraisal Interventions on Emotions During the COVID-19 Pandemic
By: Ke Wang, Amit Goldenberg, Charles Dorison, Jeremy Miller, Jennifer Lerner and James Gross
The COVID-19 pandemic is increasing negative emotions and decreasing positive emotions globally. Left unchecked, these emotional changes may have a wide array of adverse impacts. To reduce negative emotions and increase positive emotions, we will examine the impact of...
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Keywords:
COVID-19;
Emotion Regulation;
Reappraisal;
Interventions;
Health Pandemics;
Emotions;
Global Range
Wang, Ke, Amit Goldenberg, Charles Dorison, Jeremy Miller, Jennifer Lerner, and James Gross. "A Multi-country Test of Brief Reappraisal Interventions on Emotions During the COVID-19 Pandemic." Nature Human Behaviour 5, no. 8 (August 2021): 1089–1110.
- July 2021
- Supplement
Adaptive Platform Trials: The Clinical Trial of the Future? (C)
By: Ariel D. Stern and Sarah Mehta
This (C) case provides an update on the work of the Global Coalition for Adaptive Research (GCAR) and also illustrates how adaptive platform trials can nimbly respond to a global pandemic.
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Keywords:
Clinical Trials;
Drug Trials;
Drug Testing;
Cancer Trials;
Glioblastoma;
Platform Trials;
Adaptive Trials;
Adaptive Platform Trials;
Health Testing and Trials;
Health Care and Treatment;
Business Strategy;
Health Industry;
United States
Stern, Ariel D., and Sarah Mehta. "Adaptive Platform Trials: The Clinical Trial of the Future? (C)." Harvard Business School Supplement 622-012, July 2021.