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- 2022
- Working Paper
Nailing Prediction: Experimental Evidence on the Value of Tools in Predictive Model Development
Predictive model development is understudied despite its importance to modern businesses. Although prior discussions highlight advances in methods (along the dimensions of data, computing power, and algorithms) as the primary driver of model quality, the value of tools...
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Keywords:
Analytics and Data Science
Yue, Daniel, Paul Hamilton, and Iavor Bojinov. "Nailing Prediction: Experimental Evidence on the Value of Tools in Predictive Model Development." Harvard Business School Working Paper, No. 23-029, December 2022.
- December 7, 2022
- Article
Why Decentralized Crypto Platforms Are Weathering the Crash
By: Shai Bernstein and Scott Duke Kominers
In the past year, crypto markets dropped from $2.9 trillion in value to around $800 billion. In the wake of the collapse, crypto lenders and exchanges have been accused of fraud and other wrongdoing. What went wrong? One factor is competition. In theory, competition...
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Keywords:
Crypto Economy;
Cryptocurrency;
Financial Complexity;
Financial Crisis;
Decentralization;
Decentralized Markets;
Decentralized Autonomous Organizations;
Finance;
Market Design;
Financial Services Industry
Bernstein, Shai, and Scott Duke Kominers. "Why Decentralized Crypto Platforms Are Weathering the Crash." Harvard Business Review Digital Articles (December 7, 2022).
- 2022
- Article
OpenXAI: Towards a Transparent Evaluation of Model Explanations
By: Chirag Agarwal, Satyapriya Krishna, Eshika Saxena, Martin Pawelczyk, Nari Johnson, Isha Puri, Marinka Zitnik and Himabindu Lakkaraju
While several types of post hoc explanation methods have been proposed in recent literature, there is very little work on systematically benchmarking these methods. Here, we introduce OpenXAI, a comprehensive and extensible opensource framework for evaluating and...
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Agarwal, Chirag, Satyapriya Krishna, Eshika Saxena, Martin Pawelczyk, Nari Johnson, Isha Puri, Marinka Zitnik, and Himabindu Lakkaraju. "OpenXAI: Towards a Transparent Evaluation of Model Explanations." Advances in Neural Information Processing Systems (NeurIPS) (2022).
- November 2022
- Case
Ajax Health: A New Model for Medical Technology Innovation
By: Regina E. Herzlinger and Ben Creo
This case teaches key success factors for both startups and established medtech firms. It examines how to structure a firm to maximize financial returns. Medtech entrepreneur Duke Rohlen is proposing a new model for innovation and business growth. From 2007 to 2019,...
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- November 2022
- Case
The Battle Among Channels for Marketing Pharmaceuticals: UpScript, Pharmacy Benefit Managers, and Direct-to-Consumer Sales
By: Regina E. Herzlinger and Tiffany Farrell
Can an online pharmacy both improve the quality and speed of care for patients who need branded drugs and stabilize profits for pharmaceutical manufacturers? UpScript, after years spent achieving legal and regulatory compliance and simultaneous technological innovation...
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- October 2022
- Case
Star Magnolia Capital: Becoming Experts at Finding Experts
By: Lauren Cohen, Hao Gao, River Ewing and Grace Headinger
Shinya Deguchi, Founder and Managing Partner of Star Magnolia Capital, a Shanghai-based multi-family office (MFO), considered how to convince a new prospective family that the MFO’s endowment model approach would best suit their needs. In recent decades, there has been...
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Keywords:
China;
Asia;
Family Office;
Shanghai;
Financial Industry;
Asset Management;
Financial Instruments;
Financial Management;
Financial Strategy;
Investment;
Investment Return;
Investment Portfolio;
Human Capital;
Family Business;
Financial Services Industry;
China;
Shanghai
Cohen, Lauren, Hao Gao, River Ewing, and Grace Headinger. "Star Magnolia Capital: Becoming Experts at Finding Experts." Harvard Business School Case 223-038, October 2022.
- June 2022
- Article
A New Initiative to Track HIV Resource Allocation and Costs
By: Ryan McBain, AK Nandakumar, Michael Ruffner, Carlyn Mann, Mai Hijazi, Susanna Baker, Linden Morrison, Kalipso Chalkidou, Shufang Zhang, Iris Semini, Fern Terris-Prestholt, Steven Forsythe, Sarah Byakika, Joshua Musinguzi and Robert S. Kaplan
In early 2020, several global health institutions – including the Global Fund to Fight AIDS, Tuberculosis and Malaria; Joint United Nations Program on HIV/AIDS (UNAIDS); United States Agency for International Development; and Office of the Global AIDS Coordinator at...
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Keywords:
Activity Based Costing;
HIV;
Cost;
Health Care;
Healthcare;
Health Care and Treatment;
Activity Based Costing and Management;
Resource Allocation;
Health Industry;
Africa
McBain, Ryan, AK Nandakumar, Michael Ruffner, Carlyn Mann, Mai Hijazi, Susanna Baker, Linden Morrison, Kalipso Chalkidou, Shufang Zhang, Iris Semini, Fern Terris-Prestholt, Steven Forsythe, Sarah Byakika, Joshua Musinguzi, and Robert S. Kaplan. "A New Initiative to Track HIV Resource Allocation and Costs." Bulletin of the World Health Organization 100, no. 6 (June 2022): 358–358A.
- Working Paper
Representation and Extrapolation: Evidence from Clinical Trials
By: Marcella Alsan, Maya Durvasula, Harsh Gupta, Joshua Schwartzstein and Heidi L. Williams
This article examines the consequences and causes of low enrollment of Black patients in clinical
trials. We develop a simple model of similarity-based extrapolation that predicts that evidence is
more relevant for decision-making by physicians and patients when it...
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Keywords:
Representation;
Racial Disparity;
Health Testing and Trials;
Race;
Equality and Inequality;
Innovation and Invention;
Pharmaceutical Industry
Alsan, Marcella, Maya Durvasula, Harsh Gupta, Joshua Schwartzstein, and Heidi L. Williams. "Representation and Extrapolation: Evidence from Clinical Trials." NBER Working Paper Series, No. 30575, October 2022. (Revise and resubmit, Quarterly Journal of Economics.)
- Fall 2022
- Article
China's Political Economy and International Backlash: From Interdependence to Security Dilemma Dynamics
By: Margaret Pearson, Meg Rithmire and Kellee Tsai
Contrary to expectations that economic interdependence might lessen security conflict between China and the U.S. and its allies, much of the contestation between China and several OECD countries has focused on firms and economic links. This paper explains the...
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Pearson, Margaret, Meg Rithmire, and Kellee Tsai. "China's Political Economy and International Backlash: From Interdependence to Security Dilemma Dynamics." International Security 47, no. 2 (Fall 2022): 135–176.
- August 2022 (Revised December 2022)
- Case
Iluméxico: For Every Family to Have Power
By: Brian Trelstad, Isa Oliveres and Jenyfeer Martinez Buitrago
In 2022, Manuel Wiechers, the CEO of Iluméxico, a for-profit social enterprise that provided off-grid solar energy services in rural Mexico, was finalizing his presentation for the company’s upcoming board meeting. In the 12 years since Wiechers had co-founded...
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Keywords:
Social Entrepreneurship;
Social Enterprise;
Energy;
Energy Policy;
Energy Generation;
Energy Sources;
Growth Management;
Business and Government Relations;
Equity;
Internet and the Web;
Business Model;
Energy Industry;
Mexico;
Latin America
Trelstad, Brian, Isa Oliveres, and Jenyfeer Martinez Buitrago. "Iluméxico: For Every Family to Have Power." Harvard Business School Case 323-026, August 2022. (Revised December 2022.)
- 2022
- Working Paper
Pricing Power in Advertising Markets: Theory and Evidence
By: Matthew Gentzkow, Jesse M. Shapiro, Frank Yang and Ali Yurukoglu
Existing theories of media competition imply that advertisers will pay a lower price in equilibrium to reach consumers who multi-home across competing outlets. We generalize and extend this theoretical result and test it using data from television and social media...
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Gentzkow, Matthew, Jesse M. Shapiro, Frank Yang, and Ali Yurukoglu. "Pricing Power in Advertising Markets: Theory and Evidence." NBER Working Paper Series, No. 30278, July 2022.
- June 2022 (Revised October 2022)
- Background Note
Digital Commerce and Delivery: Preparing Food and Retail Value Chains for a 50-50 World
By: William R. Kerr, Daniel O'Connor, Paige Boehmcke and Will Ensor
Increasing digitalization of grocery retail and quick commerce reveals insights about managing complex supply chains at scale and shifting revenue streams from product sales to data monetization. How are the roles of retailers changing? What happens if marginal cost...
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Keywords:
Grocery Delivery;
Grocery;
Digitalization;
Fulfillment;
Delivery;
Supply Chain;
Disruption;
Food;
Supply Chain Management;
Market Design;
Trends;
Value Creation;
Goods and Commodities;
Customer Value and Value Chain;
Digital Transformation;
Retail Industry;
Food and Beverage Industry;
United States;
China
Kerr, William R., Daniel O'Connor, Paige Boehmcke, and Will Ensor. "Digital Commerce and Delivery: Preparing Food and Retail Value Chains for a 50-50 World." Harvard Business School Background Note 822-108, June 2022. (Revised October 2022.)
- 2022
- Article
Exploring Counterfactual Explanations Through the Lens of Adversarial Examples: A Theoretical and Empirical Analysis.
By: Martin Pawelczyk, Chirag Agarwal, Shalmali Joshi, Sohini Upadhyay and Himabindu Lakkaraju
As machine learning (ML) models become more widely deployed in high-stakes applications, counterfactual explanations have emerged as key tools for providing actionable model explanations in practice. Despite the growing popularity of counterfactual explanations, a...
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Keywords:
Machine Learning Models;
Counterfactual Explanations;
Adversarial Examples;
Mathematical Methods
Pawelczyk, Martin, Chirag Agarwal, Shalmali Joshi, Sohini Upadhyay, and Himabindu Lakkaraju. "Exploring Counterfactual Explanations Through the Lens of Adversarial Examples: A Theoretical and Empirical Analysis." Proceedings of the International Conference on Artificial Intelligence and Statistics (AISTATS) 25th (2022).
- March 2022
- Case
Pakistan Rising: Bazaar's Growth Story (A)
By: Paul A. Gompers and Gamze Yucaoglu
The case opens in September 2021 as Hamza Jawaid and Saad Jangda, co-founders of Bazaar technologies (Bazaar), the Pakistani high growth B2B e-commerce marketplace, are contemplating whether the year-and-a half old startup should also venture into offering financing to...
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- March 2022
- Article
Estimating the Effectiveness of Permanent Price Reductions for Competing Products Using Multivariate Bayesian Structural Time Series Models
By: Fiammetta Menchetti and Iavor Bojinov
Researchers regularly use synthetic control methods for estimating causal effects when a sub-set of units receive a single persistent treatment, and the rest are unaffected by the change. In many applications, however, units not assigned to treatment are nevertheless...
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Keywords:
Causal Inference;
Partial Interference;
Synthetic Controls;
Bayesian Structural Time Series;
Mathematical Methods
Menchetti, Fiammetta, and Iavor Bojinov. "Estimating the Effectiveness of Permanent Price Reductions for Competing Products Using Multivariate Bayesian Structural Time Series Models." Annals of Applied Statistics 16, no. 1 (March 2022): 414–435.
- 2022
- Working Paper
The Disagreement Problem in Explainable Machine Learning: A Practitioner's Perspective
By: Satyapriya Krishna, Tessa Han, Alex Gu, Javin Pombra, Shahin Jabbari, Steven Wu and Himabindu Lakkaraju
As various post hoc explanation methods are increasingly being leveraged to explain complex models in high-stakes settings, it becomes critical to develop a deeper understanding of if and when the explanations output by these methods disagree with each other, and how...
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Krishna, Satyapriya, Tessa Han, Alex Gu, Javin Pombra, Shahin Jabbari, Steven Wu, and Himabindu Lakkaraju. "The Disagreement Problem in Explainable Machine Learning: A Practitioner's Perspective." Working Paper, 2022.
- February 2022
- Case
NFX Capital and Moov Technologies
By: Scott Duke Kominers and Nicole Tempest Keller
In July 2019, James Currier, a general partner at San Francisco-based NFX Ventures, was considering a seed stage investment of $1.5 million in Moov Technologies, a B2B marketplace for used industrial equipment. NFX was a venture capital firm focused on seed-stage...
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Keywords:
Venture Capital;
Network Effects;
Marketplace Matching;
Digital Platforms;
Market Design;
Applications and Software;
Semiconductor Industry;
Financial Services Industry;
San Francisco
Kominers, Scott Duke, and Nicole Tempest Keller. "NFX Capital and Moov Technologies." Harvard Business School Case 822-045, February 2022.
- 2022
- Working Paper
How Do Copayment Coupons Affect Branded Drug Prices and Quantities Purchased?
By: Leemore S. Dafny, Kate Ho and Edward Kong
Drug copayment coupons to reduce patient cost-sharing have become nearly ubiquitous for high-priced brand-name prescription drugs. Medicare bans such coupons on the grounds that they are kickbacks that induce utilization, but they are commonly used by...
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Keywords:
Prescription Drugs;
Coupons;
Impact;
Health Care and Treatment;
Markets;
Price;
Spending;
Pharmaceutical Industry;
United States
Dafny, Leemore S., Kate Ho, and Edward Kong. "How Do Copayment Coupons Affect Branded Drug Prices and Quantities Purchased?" NBER Working Paper Series, No. 29735, February 2022.
- January 2022 (Revised August 2022)
- Case
Hello Heart: The Next Generation of Chronic Disease Management Apps
By: Ariel D. Stern and Danielle Golan
Hello Heart, a hypertension management app debated whether to go deep and cover other heart conditions, or to expand its solution to other chronic conditions.
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Keywords:
Health;
Health Care and Treatment;
Information Technology;
Mobile and Wireless Technology;
Analysis;
Business Startups;
Transition;
Customer Focus and Relationships;
Customer Satisfaction;
Decision Making;
Demographics;
Design;
Entrepreneurship;
Venture Capital;
Technological Innovation;
Growth and Development Strategy;
Product Launch;
Product Design;
Product Development;
Business Strategy;
Competitive Strategy;
Competitive Advantage;
Customization and Personalization;
Business Growth and Maturation;
Business Model;
Strategy;
Applications and Software;
Health Industry;
Technology Industry;
Israel;
United States
Stern, Ariel D., and Danielle Golan. "Hello Heart: The Next Generation of Chronic Disease Management Apps." Harvard Business School Case 622-061, January 2022. (Revised August 2022.)
- January 2022
- Case
Somatus: Value-Based Kidney Care (A)
By: Ariel D. Stern, Robert S. Huckman and Sarah Mehta
When Dr. Ikenna Okezie founded Somatus, a value-based kidney care provider, his goal had been nothing short of transforming kidney care delivery in the United States. Rather than relying on dialysis, a costly and intensive treatment for late-stage kidney disease, the...
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Keywords:
Business Startups;
Disruption;
Entrepreneurship;
Health;
Health Care and Treatment;
Health Disorders;
Medical Specialties;
Innovation and Invention;
Disruptive Innovation;
Management;
Strategy;
Business Strategy;
Value;
Value Creation;
Health Industry;
United States;
Virginia
Stern, Ariel D., Robert S. Huckman, and Sarah Mehta. "Somatus: Value-Based Kidney Care (A)." Harvard Business School Case 622-009, January 2022.