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All HBS Web
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- Faculty Publications (78)
- December 2020 (Revised April 2021)
- Case
IBM Watson at MD Anderson Cancer Center
By: Shane Greenstein, Mel Martin and Sarkis Agaian
After discovering that their cancer diagnostic tool, designed to leverage the cloud computing power of IBM Watson, needed greater integration into the clinical processes at the MD Anderson Cancer Center, the development team had difficult choices to make. The Oncology...
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Keywords:
Decision Making;
Innovation Strategy;
Knowledge Management;
Knowledge Use and Leverage;
Operations;
Failure;
Information Technology;
Applications and Software;
Health Care and Treatment;
Product Development;
Health Industry;
Information Technology Industry;
Technology Industry;
United States;
Houston;
Texas
Greenstein, Shane, Mel Martin, and Sarkis Agaian. "IBM Watson at MD Anderson Cancer Center." Harvard Business School Case 621-022, December 2020. (Revised April 2021.)
- November 2020 (Revised May 2021)
- Technical Note
Tales of Life-changing Innovations: Safe and Cheap Diagnostics | Note on the Development of Ultrasound Scanning (through 2000)
By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins
Bhidé, Amar, Srikant M. Datar, and Katherine Stebbins. "Tales of Life-changing Innovations: Safe and Cheap Diagnostics | Note on the Development of Ultrasound Scanning (through 2000)." Harvard Business School Technical Note 321-054, November 2020. (Revised May 2021.)
- October 2020
- Technical Note
Organizational Reinvention
By: Ryan Raffaelli
This note is designed to introduce students to the fundamental concepts of leading innovation in established organizations. Reinvention is a process whereby organizations respond to changes in the environment that threaten their core business model, technologies,...
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Keywords:
Innovation And Strategy;
Leadership And Change Management;
Organizational Ambidexterity;
Exploration And Exploitation;
Innovation and Management;
Innovation Leadership;
Leading Change;
Technology Adoption;
Change Management;
Organizational Change and Adaptation
Raffaelli, Ryan. "Organizational Reinvention." Harvard Business School Technical Note 421-041, October 2020.
- August 2020 (Revised January 2022)
- Case
1928 Diagnostics: Fighting Antibiotics Resistance
By: Ariel D. Stern and Daniela Beyersdorfer
In 2019, the co-founders of the Swedish medical start-up 1928 Diagnostics, CEO Dr. Kristina Lagerstedt and COO Dr. Susanne Staaf, had to pick the right business model to commercialize their novel technology to hospitals and health care providers. Developed in...
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Keywords:
Health Care and Treatment;
Entrepreneurship;
Leadership;
Science-Based Business;
Growth and Development Strategy;
Business Growth and Maturation;
Business Model;
Information Technology;
Digital Platforms;
Health Disorders;
Market Entry and Exit;
Value Creation;
Business and Stakeholder Relations;
Health Industry;
Medical Devices and Supplies Industry;
Technology Industry;
Europe;
Sweden
Stern, Ariel D., and Daniela Beyersdorfer. "1928 Diagnostics: Fighting Antibiotics Resistance." Harvard Business School Case 621-025, August 2020. (Revised January 2022.)
- Article
Assessing the Training Costs and Work of Diagnostic Radiology Residents Using Key Performance Indicators—An Observational Study
By: Robert S. Kaplan, Marta E. Heilbrun, Brad Poss, Luca Boi, Yoshimi Anzai and Nan Hu
Kaplan, Robert S., Marta E. Heilbrun, Brad Poss, Luca Boi, Yoshimi Anzai, and Nan Hu. "Assessing the Training Costs and Work of Diagnostic Radiology Residents Using Key Performance Indicators—An Observational Study." Academic Radiology 27, no. 7 (July 2020): 1025–1032.
- Article
Development of a Deep Learning Algorithm for Periapical Disease Detection in Dental Radiographs
By: Michael G. Endres, Florian Hillen, Marios Salloumis, Ahmad R. Sedaghat, Stefan M. Niehues, Olivia Quatela, Henning Hanken, Ralf Smeets, Benedicta Beck-Broichsitter, Carsten Rendenbach, Karim R. Lakhani, Max Helland and Robert A. Gaudin
Periapical radiolucencies, which can be detected on panoramic radiographs, are one of the most common radiographic findings in dentistry and have a differential diagnosis including infections, granuloma, cysts, and tumors. In this study, we seek to investigate the...
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Keywords:
Artificial Intelligence;
Diagnosis;
Computer-assisted;
Image Interpretation;
Machine Learning;
Radiography;
Panoramic Radiograph;
AI and Machine Learning
Endres, Michael G., Florian Hillen, Marios Salloumis, Ahmad R. Sedaghat, Stefan M. Niehues, Olivia Quatela, Henning Hanken, Ralf Smeets, Benedicta Beck-Broichsitter, Carsten Rendenbach, Karim R. Lakhani, Max Helland, and Robert A. Gaudin. "Development of a Deep Learning Algorithm for Periapical Disease Detection in Dental Radiographs." Diagnostics 10, no. 6 (June 2020).
- 26 Apr 2020
- Other Presentation
Towards Modeling the Variability of Human Attention
By: Kuno Kim, Megumi Sano, Julian De Freitas, Daniel Yamins and Nick Haber
Children exhibit extraordinary exploratory behaviors hypothesized to contribute to the building of models of their world. Harnessing this capacity in artificial systems promises not only more flexible technology but also cognitive models of the developmental processes...
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Keywords:
Exploratory Learning Behaviors;
Modeling;
Artificial Intelligence;
AI and Machine Learning
Kim, Kuno, Megumi Sano, Julian De Freitas, Daniel Yamins, and Nick Haber. "Towards Modeling the Variability of Human Attention." In Bridging AI and Cognitive Science (BAICS) Workshop. 8th International Conference on Learning Representations (ICLR), April 26, 2020.
- March 2020
- Article
Diagnosing Missing Always at Random in Multivariate Data
By: Iavor I. Bojinov, Natesh S. Pillai and Donald B. Rubin
Models for analyzing multivariate data sets with missing values require strong, often assessable, assumptions. The most common of these is that the mechanism that created the missing data is ignorable—a twofold assumption dependent on the mode of inference. The first...
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Keywords:
Missing Data;
Diagnostic Tools;
Sensitivity Analysis;
Hypothesis Testing;
Missing At Random;
Row Exchangeability;
Analytics and Data Science;
Mathematical Methods
Bojinov, Iavor I., Natesh S. Pillai, and Donald B. Rubin. "Diagnosing Missing Always at Random in Multivariate Data." Biometrika 107, no. 1 (March 2020): 246–253.
- 2019
- Case
Krueger-Gilbert Health Physics: Can a Serial Acquisition Strategy Work for a Diagnostic Consulting Firm?
By: Jason Pananos and A.J. Wasserstein
Pananos, Jason, and A.J. Wasserstein. "Krueger-Gilbert Health Physics: Can a Serial Acquisition Strategy Work for a Diagnostic Consulting Firm?" Yale School of Management Case 19-014, 2019.
- 2021
- Working Paper
Computed Tomography: Case Histories of Significant Medical Advances
By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins
We describe how Computed Tomography (CT) scanners—that combine x-rays and computers to image soft tissues of the brain and other organs—have become a widely used diagnostic tool. Specifically, we chronicle the: 1) the initial development of CT technology and markets...
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Keywords:
Health Care and Treatment;
Technological Innovation;
Innovation Strategy;
Technology Adoption;
Collaborative Innovation and Invention;
Innovation and Invention;
Governing Rules, Regulations, and Reforms
Bhidé, Amar, Srikant M. Datar, and Katherine Stebbins. "Computed Tomography: Case Histories of Significant Medical Advances." Harvard Business School Working Paper, No. 20-004, July 2019. (Revised May 2021.)
- 2021
- Working Paper
Development of Ultrasound Scanning: Case Histories of Significant Medical Advances
By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins
We describe how efforts on multiple fronts, including advocacy, training and technological development made ultrasound the second most used diagnostic imaging technology (after X-rays). Specifically, we chronicle: 1) ultrasound’s development and introduction in the...
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Keywords:
Health Care and Treatment;
Technological Innovation;
Innovation Strategy;
Technology Adoption;
Collaborative Innovation and Invention;
Innovation and Invention;
Governing Rules, Regulations, and Reforms
Bhidé, Amar, Srikant M. Datar, and Katherine Stebbins. "Development of Ultrasound Scanning: Case Histories of Significant Medical Advances." Harvard Business School Working Paper, No. 20-003, July 2019. (Revised May 2021.)
- 2021
- Working Paper
Gastrointestinal Endoscopy: Case Histories of Significant Medical Advances
By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins
We describe how endoscopy transformed the diagnosis of ulcers, cancerous polyps and other diseases of the alimentary canal and enabled “minimally invasive” surgeries to treat such diseases. Specifically, we chronicle how: 1) flexible glass fiber instruments in the...
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Keywords:
Health Care and Treatment;
Technological Innovation;
Innovation Strategy;
Technology Adoption;
Collaborative Innovation and Invention;
Innovation and Invention;
Governing Rules, Regulations, and Reforms
Bhidé, Amar, Srikant M. Datar, and Katherine Stebbins. "Gastrointestinal Endoscopy: Case Histories of Significant Medical Advances." Harvard Business School Working Paper, No. 20-005, July 2019. (Revised May 2021.)
- 2021
- Working Paper
Magnetic Resonance Imaging: Case Histories of Significant Medical Advances
By: Srikant M. Datar, Amar Bhidé and Katherine Stebbins
We describe how and why Magnetic Resource Imaging (MRI) came to complement – and partially replace -- computed tomography (CT) imaging of soft tissue. Specifically we chronicle: 1) the development of foundational techniques and prototypes (through the 1970s); 2)...
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Keywords:
Health Care and Treatment;
Technological Innovation;
Innovation Strategy;
Technology Adoption;
Collaborative Innovation and Invention;
Innovation and Invention;
Governing Rules, Regulations, and Reforms
Datar, Srikant M., Amar Bhidé, and Katherine Stebbins. "Magnetic Resonance Imaging: Case Histories of Significant Medical Advances." Harvard Business School Working Paper, No. 20-001, July 2019. (Revised June 2021.)
- 2019
- Chapter
Characterizing the Drug Development Pipeline for Precision Medicines
By: Amitabh Chandra, Craig Garthwaite and Ariel Dora Stern
BOOK ABSTRACT: Personalized and precision medicine (PPM)—the targeting of therapies according to an individual’s genetic, environmental, or lifestyle characteristics—is becoming an increasingly important approach in health care treatment and prevention. The advancement...
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Chandra, Amitabh, Craig Garthwaite, and Ariel Dora Stern. "Characterizing the Drug Development Pipeline for Precision Medicines." Chap. 5 in Economic Dimensions of Personalized and Precision Medicine, edited by Ernest R. Berndt, Dana P. Goldman, and John W. Rowe, 115–158. University of Chicago Press, 2019.
- 2022
- Working Paper
A Preference for Revision Absent Objective Improvement
By: Ximena Garcia-Rada, Leslie K. John, Ed O’Brien and Michael I. Norton
From downloading never-ending updates to tracking ever-newer releases, consumers today are surrounded by revised offerings that purport to have improved upon what was previously available. Although revising things often makes them better, the current research reveals...
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Keywords:
Product Change;
Versioning;
Expectancy Effects;
Heuristics;
Intuitive Processing;
Product Marketing;
Change;
Perception;
Consumer Behavior
Garcia-Rada, Ximena, Leslie K. John, Ed O’Brien, and Michael I. Norton. "A Preference for Revision Absent Objective Improvement." Harvard Business School Working Paper, No. 19-087, February 2019. (Revised February 2022. Revise and resubmit, Journal of Marketing Research.)
- 2018
- Working Paper
Diagnostic Bubbles
By: Pedro Bordalo, Nicola Gennaioli, Spencer Yongwook Kwon and Andrei Shleifer
We introduce diagnostic expectations into a standard setting of price formation in which investors learn about the fundamental value of an asset and trade it. We study the interaction of diagnostic expectations with two well-known mechanisms: learning from prices and...
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Bordalo, Pedro, Nicola Gennaioli, Spencer Yongwook Kwon, and Andrei Shleifer. "Diagnostic Bubbles." NBER Working Paper Series, No. 25399, December 2018.
- February 2018
- Article
Diagnostic Expectations and Credit Cycles
By: Pedro Bordalo, Nicola Gennaioli and Andrei Shleifer
Bordalo, Pedro, Nicola Gennaioli, and Andrei Shleifer. "Diagnostic Expectations and Credit Cycles." Journal of Finance 73, no. 1 (February 2018): 199–227.
- Article
Stop the Meeting Madness: How to Free Up Time for Meaningful Work
By: Leslie Perlow, Constance Noonan Hadley and Eunice Eun
Many executives feel overwhelmed by meetings, and no wonder: On average, they spend nearly 23 hours a week in them, up from less than 10 hours in the 1960s. What’s more, the meetings are often poorly timed, badly run, or both. We can all joke about how painful they...
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Keywords:
Time Management;
Performance Efficiency;
Organizational Change and Adaptation;
Performance Improvement
Perlow, Leslie, Constance Noonan Hadley, and Eunice Eun. "Stop the Meeting Madness: How to Free Up Time for Meaningful Work." Harvard Business Review 95, no. 4 (July–August 2017): 62–69.
- December 2016 (Revised May 2018)
- Module Note
Strategy Execution Module 15: Using the Levers of Control to Implement Strategy
By: Robert Simons
This module reading pulls together key concepts and techniques from the Strategy Execution series into an integrated model—the levers of control. The four levers are: (1) belief systems, (2) boundary systems, (3) diagnostic control systems, and (4) interactive control...
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Keywords:
Management Control Systems;
Implementing Strategy;
Execution;
Levers Of Control;
Balancing Innovation And Control;
Managing Growing Businesses;
Turn Around Management;
Human Behavior;
Organizational Life Cycle;
Strategy;
Management Systems;
Performance;
Measurement and Metrics;
Management Analysis, Tools, and Techniques;
Behavior
Simons, Robert. "Strategy Execution Module 15: Using the Levers of Control to Implement Strategy." Harvard Business School Module Note 117-115, December 2016. (Revised May 2018.)
- November 2016 (Revised December 2016)
- Module Note
Strategy Execution Module 13: Identifying Strategic Risk
By: Robert Simons
This module reading begins by describing the three sources of strategic risk—operations risk, asset impairment risk, and competitive risk—and demonstrates how these risks can undermine an entire business. To assist in the identification of these risks, the risk...
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Keywords:
Management Control Systems;
Implementing Strategy;
Execution;
Risk Assessment;
Operational Control;
Asset Impairment;
Franchise Risk;
Fraud;
Strategy;
Information Management
Simons, Robert. "Strategy Execution Module 13: Identifying Strategic Risk." Harvard Business School Module Note 117-113, November 2016. (Revised December 2016.)