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Publications

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    • Faculty Publications  (53)

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    • All HBS Web  (309)
      • Faculty Publications  (53)

      Breakthrough Innovation Remove Breakthrough Innovation →

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      • 2022
      • Working Paper

      Regulatory Incentives for Innovation: The FDA's Breakthrough Therapy Designation

      By: Amitabh Chandra, Jennifer Kao, Kathleen Miller and Ariel D. Stern
      Regulators of new products confront a tradeoff between speeding a new product to market and collecting additional product quality information. The FDA’s Breakthrough Therapy Designation (BTD) provides an opportunity to understand if a regulator can use new policy to...  View Details
      Keywords: Research and Development; Governing Rules, Regulations, and Reforms; Product Development
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      Chandra, Amitabh, Jennifer Kao, Kathleen Miller, and Ariel D. Stern. "Regulatory Incentives for Innovation: The FDA's Breakthrough Therapy Designation." NBER Working Paper Series, No. 30712, December 2022.
      • 13 Oct 2022
      • Other Presentation

      4 Business Ideas That Changed the World: Disruptive Innovation

      By: Amy Bernstein, Rita McGrath, Felix Oberholzer-Gee and Derek van Bever
      A roundtable conversation takes stock of Clayton Christensen’s influential theory. This first in a series of roundtable conversations assessing the origins and impact of four breakthrough ideas.

      In the 1980s, Clayton Christensen cofounded a startup that...  View Details
      Keywords: Disruptive Innovation
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      "4 Business Ideas That Changed the World: Disruptive Innovation." HBR IdeaCast (podcast), Harvard Business Review Group, October 13, 2022.
      • Working Paper

      Representation and Extrapolation: Evidence from Clinical Trials

      By: Marcella Alsan, Maya Durvasula, Harsh Gupta, Joshua Schwartzstein and Heidi L. Williams
      This article examines the consequences and causes of low enrollment of Black patients in clinical trials. We develop a simple model of similarity-based extrapolation that predicts that evidence is more relevant for decision-making by physicians and patients when it...  View Details
      Keywords: Representation; Racial Disparity; Health Testing and Trials; Race; Equality and Inequality; Innovation and Invention; Pharmaceutical Industry
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      Alsan, Marcella, Maya Durvasula, Harsh Gupta, Joshua Schwartzstein, and Heidi L. Williams. "Representation and Extrapolation: Evidence from Clinical Trials." NBER Working Paper Series, No. 30575, October 2022. (Revise and resubmit, Quarterly Journal of Economics.)
      • March 5, 2022
      • Article

      Hospital Capacity Shortages: An SEC-Backed Transparency “PULL” Will Open Beds Faster Than a “PUSH” by HHS

      By: Regina E. Herzlinger
      In the new normal of ongoing pandemics, hospital bed shortages will continue. Healthcare innovation expert and author of the upcoming book Innovating in Healthcare: Creating Breakthrough Services, Products, and Business Models (Wiley, 2023, 978-1119543008), HBS...  View Details
      Keywords: Hospital Capacity; Access To Care; Health Pandemics; Health Care and Treatment; Performance Capacity; Planning
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      Herzlinger, Regina E. "Hospital Capacity Shortages: An SEC-Backed Transparency “PULL” Will Open Beds Faster Than a “PUSH” by HHS." Healthcare Business Today (March 5, 2022).
      • December 2021
      • Article

      The Evolutionary Nature of Breakthrough Innovation: An Empirical Investigation of Firm Search Strategies

      By: Dominika Kinga Randle and Gary P. Pisano
      Breakthrough innovation has been an important topic of study for generations of scholars. Previous research in this domain has focused on exploring the way breakthroughs emerge from cumulative combination and recombination of prior technologies and knowledge components...  View Details
      Keywords: Breakthrough Innovation; Exploration And Exploitation; Search Strategy; Innovation and Invention; Technological Innovation; Strategy
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      Randle, Dominika Kinga, and Gary P. Pisano. "The Evolutionary Nature of Breakthrough Innovation: An Empirical Investigation of Firm Search Strategies." Strategy Science 6, no. 4 (December 2021): 290–304.
      • Article

      Drive Innovation with Better Decision-Making

      By: Linda A. Hill, Emily Tedards and Taran Swan
      Despite their embrace of agile methods, many firms striving to innovate are struggling to produce breakthrough ideas. A key culprit, according to the authors, is an outdated, inefficient approach to decision-making. Today’s discovery-driven innovation processes involve...  View Details
      Keywords: Innovation and Invention; Decision Making; Decision Choices and Conditions; Organizational Change and Adaptation
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      Hill, Linda A., Emily Tedards, and Taran Swan. "Drive Innovation with Better Decision-Making." Harvard Business Review 99, no. 6 (November–December 2021): 70–79.
      • November 2021 (Revised January 2022)
      • Case

      Nicole M. Jones and The Hangar℠: Delta Air Lines' Global Innovation Center

      By: Linda A. Hill and Emily Tedards
      In 2016, Nicole M. Jones was hired to lead The Hangar, Delta Air Lines’ new innovation center in Atlanta, Georgia. Delta’s leadership had intended for The Hangar to catalyze a new approach to innovation at the company. After conducting three months of research on...  View Details
      Keywords: Innovation Lab; Breakthrough Innovation; Biometric Technology; Innovation and Invention; Leadership; Innovation and Management; Collaborative Innovation and Invention; Innovation Strategy; Technological Innovation; Georgia (state, US)
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      Hill, Linda A., and Emily Tedards. "Nicole M. Jones and The Hangar℠: Delta Air Lines' Global Innovation Center." Harvard Business School Case 422-042, November 2021. (Revised January 2022.)
      • Article

      What Evolution Can Teach Us About Innovation

      By: Noubar Afeyan and Gary P. Pisano
      Many people believe that the process for achieving breakthrough innovations is chaotic, random, and unmanageable. But that view is flawed, the authors argue. Breakthroughs can be systematically generated using a process modeled on the principles that drive evolution in...  View Details
      Keywords: Breakthrough Innovation; Variance Generation; Selection Pressure; Emergent Discovery; Innovation and Invention; Value Creation; Innovation Leadership
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      Afeyan, Noubar, and Gary P. Pisano. "What Evolution Can Teach Us About Innovation." Harvard Business Review 99, no. 5 (September–October 2021): 62–72.
      • 16 Jun 2021
      • Interview

      Harvard Business School: How to Build Fearless Organizations

      By: Amy C. Edmondson and Ron Lovett
      Our guest is Amy Edmondson - Professor of Leadership and Management at Harvard Business School. Amy has authored multiple books, including her most recent, The Fearless Organization: Creating Psychological Safety in the Workplace for Learning, Innovation and...  View Details
      Keywords: Psychological Safety; Organizational Culture; Leadership; Diversity; Communication
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      "Harvard Business School: How to Build Fearless Organizations." No. 51. Scaling Culture (podcast), June 16, 2021.
      • 2020
      • Working Paper

      The Evolutionary Nature of Breakthrough Innovation: Re-Evaluating the Exploration vs. Exploitation Dichotomy

      By: Dominika K. Sarnecka and Gary P. Pisano
      Over the past few decades, a consensus has emerged that breakthrough innovations emerge from exploration of novel terrain while more routine innovations are the product of exploitation. In this paper, we revisit this explore versus exploit dichotomy with an analysis...  View Details
      Keywords: Breakthrough Innovation; Exploration And Exploitation; Innovation and Invention; Technological Innovation
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      Sarnecka, Dominika K., and Gary P. Pisano. "The Evolutionary Nature of Breakthrough Innovation: Re-Evaluating the Exploration vs. Exploitation Dichotomy." Harvard Business School Working Paper, No. 21-071, December 2020.
      • September 2020
      • Case

      Hot Wheels: Launching The Mixed Play Experience

      By: Elie Ofek, Andres Terech and Nicole Tempest Keller
      Chris Down, Global Brand General Manager for Hot Wheels, and his team from the Advanced Play Group within Mattel, Inc., had developed an entirely new “mixed play” product experience that blended familiar Hot Wheels play in the physical world with breakthrough play in...  View Details
      Keywords: Toys; Go-to-market Strategy; Product Development; Technological Innovation; Product Launch; Product Positioning; Decision Making; Marketing; Strategy; Los Angeles
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      Ofek, Elie, Andres Terech, and Nicole Tempest Keller. "Hot Wheels: Launching The Mixed Play Experience." Harvard Business School Case 521-017, September 2020.
      • 2020
      • Book

      Think Outside the Building: How Advanced Leaders Can Change the World One Smart Innovation at a Time

      By: Rosabeth Moss Kanter
      Over a decade ago, renowned innovation expert Rosabeth Moss Kanter co-founded and then directed Harvard’s Advanced Leadership Initiative. Her breakthrough work with hundreds of successful professionals and executives, as well as aspiring young entrepreneurs, identifies...  View Details
      Keywords: Leaders; Advanced Leadership; Advanced Leadership Initiative; Community; Change Leadership; Innovation; Problem Solving; Cross-sector Collaboration; Institutional Change; Leadership; Change; Leading Change; Communication; Innovation Leadership; Collaborative Innovation and Invention; Organizational Change and Adaptation; Business and Community Relations; Civil Society or Community
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      Kanter, Rosabeth Moss. Think Outside the Building: How Advanced Leaders Can Change the World One Smart Innovation at a Time. New York: PublicAffairs, 2020.
      • May 2019
      • Case

      The United States Air Force: 'Chaos' in the 99th Reconnaissance Squadron

      By: Francesca Gino, Jeff Huizinga and Nicole Keller
      In the spring of 2019, Lt. Col. Matthew “Chaos” Nussbaum is nearing the end of his two-year term as commander of the U.S. Air Force's 99th Reconnaissance Squadron. In this position, he has focused the majority of his energy on finding new ways to organize, train, and...  View Details
      Keywords: Empowerment; Culture; Innovation; Motivation; Military; Leadership; Organizational Culture; Change; Leading Change; Innovation Strategy; United States
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      Gino, Francesca, Jeff Huizinga, and Nicole Keller. "The United States Air Force: 'Chaos' in the 99th Reconnaissance Squadron." Harvard Business School Case 919-047, May 2019.
      • March 2018
      • Case

      X: The Foghorn Decision

      By: Robert S. Huckman, Karim R. Lakhani and Kyle R. Myers
      In February 2016, Kathy Hannun--a project leader at X, Alphabet Inc.'s so-called "moonshot factory--had to prepare a recommendation for the senior leadership of X regarding the future of Foghorn, a project she was leading to develop a carbon-neutral process for...  View Details
      Keywords: Innovation; R&D Project Management; Radical Innovation; Clean Technology; Innovation and Management; Technological Innovation; Energy; Research and Development; Projects; Management; Decision Choices and Conditions; Technology Industry; Energy Industry; Green Technology Industry; California
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      Huckman, Robert S., Karim R. Lakhani, and Kyle R. Myers. "X: The Foghorn Decision." Harvard Business School Case 618-060, March 2018.
      • January 2018
      • Case

      Flying into the Future: HondaJet

      By: Gary P. Pisano and Jesse Shulman
      This cases examine Honda’s diversification into the light jet market. In 1985, Honda initiated a secret program to develop a small jet. Over the years, the program had many ups and downs (it was almost canceled several times). Then, a breakthrough in the configuration...  View Details
      Keywords: Diversification; Technological Innovation; Growth and Development Strategy; Innovation and Management; Air Transportation Industry
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      Pisano, Gary P., and Jesse Shulman. "Flying into the Future: HondaJet." Harvard Business School Case 618-012, January 2018.
      • Article

      The Board's New Innovation Imperative: Directors Need to Rethink Their Roles and Their Attitude to Risk

      By: Linda A. Hill and George Davis
      As firms scramble for competitive advantage, boards—once the cautious voices urging management to mitigate risk—are now calling for breakthrough innovation. Indeed, avoiding risk is now seen as the riskiest proposition of all. In speaking with CEOs and board members...  View Details
      Keywords: Governing and Advisory Boards; Innovation Leadership; Risk and Uncertainty; Corporate Governance
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      Hill, Linda A., and George Davis. "The Board's New Innovation Imperative: Directors Need to Rethink Their Roles and Their Attitude to Risk." Harvard Business Review 95, no. 6 (November–December 2017): 102–109.
      • May 2017 (Revised October 2017)
      • Case

      Hyperloop Transportation Technologies: Building Breakthrough Innovations in Crowd-Powered Ecosystems

      By: Lynda M. Applegate, Terri L. Griffith and Ann Majchrzak
      Dirk Ahlborn, co-founder and CEO of Hyperloop Transportation Technologies, Inc. (HTT) looks back at the evolving organizational design and community that allows HTT to be crowd-powered. Since the founding in 2013, HTT has dealt with building an organization with less...  View Details
      Keywords: Collaboration; Crowdsourcing; Entrepreneurial Finance; Innovation; Organizational Design; Startups; Business Startups; Collaborative Innovation and Invention; Entrepreneurship; Finance; Product Development
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      Applegate, Lynda M., Terri L. Griffith, and Ann Majchrzak. "Hyperloop Transportation Technologies: Building Breakthrough Innovations in Crowd-Powered Ecosystems." Harvard Business School Case 817-134, May 2017. (Revised October 2017.)
      • 2017
      • Chapter

      Entrepreneurship in Larger Companies

      By: William R. Kerr
      Entrepreneurship in large and established companies is vital for their long-term success. Incumbent firms face many challenges ranging from global competition to digitization. In times past, being caught flat-footed might have set a company back several years, but it...  View Details
      Keywords: Corporate Entrepreneurship
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      Kerr, William R. "Entrepreneurship in Larger Companies." Chap. 27 in The Entrepreneur's Roadmap: From Concept to IPO, edited by Tim Dempsey and Bonnie Hyun, 161–164. Chicago, IL: Caxton Business & Legal, Inc., 2017.
      • December 2016
      • Background Note

      Reaching Beyond Your Organization: Empowering Innovation

      By: William R. Kerr
      Forward-thinking established companies utilize new routes for external innovation with start-ups and crowds. The reading reviews strategic partnerships, strategic investments, strategic acquisitions, and crowd-based collaborations. Case examples include Google, SK...  View Details
      Keywords: Innovation; Corporate Innovation; Collaboration; Partnerships; Innovation and Invention; Collaborative Innovation and Invention; Innovation Strategy
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      Kerr, William R. "Reaching Beyond Your Organization: Empowering Innovation." Harvard Business School Background Note 817-044, December 2016.
      • November 2016 (Revised April 2018)
      • Case

      reMarkable: e-Writing the Future

      By: Elie Ofek and Curtis Hsu
      Magnus Wanberg is the creator of reMarkable, a breakthrough e-writer device set apart from similar products on the market by having solved the frustrating “slow ink” problem typically experienced on pen-based electronic devices, thus providing a “pen and paper” like...  View Details
      Keywords: Entrepreneurial Marketing; Innovation Management; Go To Market Strategy; Marketing Plan; Target Market; Digital Devices; Consumer Electronics; Forecasting; Information Technology; Marketing Strategy; Innovation and Management; Marketing Channels; Entrepreneurship; Forecasting and Prediction; Product Marketing; Product Development; Electronics Industry
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      Ofek, Elie, and Curtis Hsu. "reMarkable: e-Writing the Future." Harvard Business School Case 517-018, November 2016. (Revised April 2018.)
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