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- 2022
- Working Paper
Regulatory Incentives for Innovation: The FDA's Breakthrough Therapy Designation
By: Amitabh Chandra, Jennifer Kao, Kathleen Miller and Ariel D. Stern
Regulators of new products confront a tradeoff between speeding a new product to market and collecting additional product quality information. The FDA’s Breakthrough Therapy Designation (BTD) provides an opportunity to understand if a regulator can use new policy to...
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Chandra, Amitabh, Jennifer Kao, Kathleen Miller, and Ariel D. Stern. "Regulatory Incentives for Innovation: The FDA's Breakthrough Therapy Designation." NBER Working Paper Series, No. 30712, December 2022.
- 13 Oct 2022
- Other Presentation
4 Business Ideas That Changed the World: Disruptive Innovation
By: Amy Bernstein, Rita McGrath, Felix Oberholzer-Gee and Derek van Bever
A roundtable conversation takes stock of Clayton Christensen’s influential theory. This first in a series of roundtable conversations assessing the origins and impact of four breakthrough ideas.
In the 1980s, Clayton Christensen cofounded a startup that... View Details
In the 1980s, Clayton Christensen cofounded a startup that... View Details
Keywords:
Disruptive Innovation
"4 Business Ideas That Changed the World: Disruptive Innovation." HBR IdeaCast (podcast), Harvard Business Review Group, October 13, 2022.
- Working Paper
Representation and Extrapolation: Evidence from Clinical Trials
By: Marcella Alsan, Maya Durvasula, Harsh Gupta, Joshua Schwartzstein and Heidi L. Williams
This article examines the consequences and causes of low enrollment of Black patients in clinical
trials. We develop a simple model of similarity-based extrapolation that predicts that evidence is
more relevant for decision-making by physicians and patients when it...
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Keywords:
Representation;
Racial Disparity;
Health Testing and Trials;
Race;
Equality and Inequality;
Innovation and Invention;
Pharmaceutical Industry
Alsan, Marcella, Maya Durvasula, Harsh Gupta, Joshua Schwartzstein, and Heidi L. Williams. "Representation and Extrapolation: Evidence from Clinical Trials." NBER Working Paper Series, No. 30575, October 2022. (Revise and resubmit, Quarterly Journal of Economics.)
- March 5, 2022
- Article
Hospital Capacity Shortages: An SEC-Backed Transparency “PULL” Will Open Beds Faster Than a “PUSH” by HHS
In the new normal of ongoing pandemics, hospital bed shortages will continue. Healthcare innovation expert and author of the upcoming book Innovating in Healthcare: Creating Breakthrough Services, Products, and Business Models (Wiley, 2023, 978-1119543008), HBS...
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Keywords:
Hospital Capacity;
Access To Care;
Health Pandemics;
Health Care and Treatment;
Performance Capacity;
Planning
Herzlinger, Regina E. "Hospital Capacity Shortages: An SEC-Backed Transparency “PULL” Will Open Beds Faster Than a “PUSH” by HHS." Healthcare Business Today (March 5, 2022).
- December 2021
- Article
The Evolutionary Nature of Breakthrough Innovation: An Empirical Investigation of Firm Search Strategies
By: Dominika Kinga Randle and Gary P. Pisano
Breakthrough innovation has been an important topic of study for generations of scholars. Previous research in this domain has focused on exploring the way breakthroughs emerge from cumulative combination and recombination of prior technologies and knowledge components...
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Keywords:
Breakthrough Innovation;
Exploration And Exploitation;
Search Strategy;
Innovation and Invention;
Technological Innovation;
Strategy
Randle, Dominika Kinga, and Gary P. Pisano. "The Evolutionary Nature of Breakthrough Innovation: An Empirical Investigation of Firm Search Strategies." Strategy Science 6, no. 4 (December 2021): 290–304.
- Article
Drive Innovation with Better Decision-Making
By: Linda A. Hill, Emily Tedards and Taran Swan
Despite their embrace of agile methods, many firms striving to innovate are struggling to produce breakthrough ideas. A key culprit, according to the authors, is an outdated, inefficient approach to decision-making. Today’s discovery-driven innovation processes involve...
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Keywords:
Innovation and Invention;
Decision Making;
Decision Choices and Conditions;
Organizational Change and Adaptation
Hill, Linda A., Emily Tedards, and Taran Swan. "Drive Innovation with Better Decision-Making." Harvard Business Review 99, no. 6 (November–December 2021): 70–79.
- November 2021 (Revised January 2022)
- Case
Nicole M. Jones and The Hangar℠: Delta Air Lines' Global Innovation Center
By: Linda A. Hill and Emily Tedards
In 2016, Nicole M. Jones was hired to lead The Hangar, Delta Air Lines’ new innovation center in Atlanta, Georgia. Delta’s leadership had intended for The Hangar to catalyze a new approach to innovation at the company. After conducting three months of research on...
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Keywords:
Innovation Lab;
Breakthrough Innovation;
Biometric Technology;
Innovation and Invention;
Leadership;
Innovation and Management;
Collaborative Innovation and Invention;
Innovation Strategy;
Technological Innovation;
Georgia (state, US)
Hill, Linda A., and Emily Tedards. "Nicole M. Jones and The Hangar℠: Delta Air Lines' Global Innovation Center." Harvard Business School Case 422-042, November 2021. (Revised January 2022.)
- Article
What Evolution Can Teach Us About Innovation
By: Noubar Afeyan and Gary P. Pisano
Many people believe that the process for achieving breakthrough innovations is chaotic, random, and unmanageable. But that view is flawed, the authors argue. Breakthroughs can be systematically generated using a process modeled on the principles that drive evolution in...
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Keywords:
Breakthrough Innovation;
Variance Generation;
Selection Pressure;
Emergent Discovery;
Innovation and Invention;
Value Creation;
Innovation Leadership
Afeyan, Noubar, and Gary P. Pisano. "What Evolution Can Teach Us About Innovation." Harvard Business Review 99, no. 5 (September–October 2021): 62–72.
- 16 Jun 2021
- Interview
Harvard Business School: How to Build Fearless Organizations
By: Amy C. Edmondson and Ron Lovett
Our guest is Amy Edmondson - Professor of Leadership and Management at Harvard Business School. Amy has authored multiple books, including her most recent, The Fearless Organization: Creating Psychological Safety in the Workplace for Learning, Innovation and...
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"Harvard Business School: How to Build Fearless Organizations." No. 51. Scaling Culture (podcast), June 16, 2021.
- 2020
- Working Paper
The Evolutionary Nature of Breakthrough Innovation: Re-Evaluating the Exploration vs. Exploitation Dichotomy
By: Dominika K. Sarnecka and Gary P. Pisano
Over the past few decades, a consensus has emerged that breakthrough innovations emerge from exploration of novel terrain while more routine innovations are the product of exploitation. In this paper, we revisit this explore versus exploit dichotomy with an analysis...
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Keywords:
Breakthrough Innovation;
Exploration And Exploitation;
Innovation and Invention;
Technological Innovation
Sarnecka, Dominika K., and Gary P. Pisano. "The Evolutionary Nature of Breakthrough Innovation: Re-Evaluating the Exploration vs. Exploitation Dichotomy." Harvard Business School Working Paper, No. 21-071, December 2020.
- September 2020
- Case
Hot Wheels: Launching The Mixed Play Experience
By: Elie Ofek, Andres Terech and Nicole Tempest Keller
Chris Down, Global Brand General Manager for Hot Wheels, and his team from the Advanced Play Group within Mattel, Inc., had developed an entirely new “mixed play” product experience that blended familiar Hot Wheels play in the physical world with breakthrough play in...
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Keywords:
Toys;
Go-to-market Strategy;
Product Development;
Technological Innovation;
Product Launch;
Product Positioning;
Decision Making;
Marketing;
Strategy;
Los Angeles
Ofek, Elie, Andres Terech, and Nicole Tempest Keller. "Hot Wheels: Launching The Mixed Play Experience." Harvard Business School Case 521-017, September 2020.
- 2020
- Book
Think Outside the Building: How Advanced Leaders Can Change the World One Smart Innovation at a Time
Over a decade ago, renowned innovation expert Rosabeth Moss Kanter co-founded and then directed Harvard’s Advanced Leadership Initiative. Her breakthrough work with hundreds of successful professionals and executives, as well as aspiring young entrepreneurs, identifies...
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Keywords:
Leaders;
Advanced Leadership;
Advanced Leadership Initiative;
Community;
Change Leadership;
Innovation;
Problem Solving;
Cross-sector Collaboration;
Institutional Change;
Leadership;
Change;
Leading Change;
Communication;
Innovation Leadership;
Collaborative Innovation and Invention;
Organizational Change and Adaptation;
Business and Community Relations;
Civil Society or Community
Kanter, Rosabeth Moss. Think Outside the Building: How Advanced Leaders Can Change the World One Smart Innovation at a Time. New York: PublicAffairs, 2020.
- May 2019
- Case
The United States Air Force: 'Chaos' in the 99th Reconnaissance Squadron
By: Francesca Gino, Jeff Huizinga and Nicole Keller
In the spring of 2019, Lt. Col. Matthew “Chaos” Nussbaum is nearing the end of his two-year term as commander of the U.S. Air Force's 99th Reconnaissance Squadron. In this position, he has focused the majority of his energy on finding new ways to organize, train, and...
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Keywords:
Empowerment;
Culture;
Innovation;
Motivation;
Military;
Leadership;
Organizational Culture;
Change;
Leading Change;
Innovation Strategy;
United States
Gino, Francesca, Jeff Huizinga, and Nicole Keller. "The United States Air Force: 'Chaos' in the 99th Reconnaissance Squadron." Harvard Business School Case 919-047, May 2019.
- March 2018
- Case
X: The Foghorn Decision
In February 2016, Kathy Hannun--a project leader at X, Alphabet Inc.'s so-called "moonshot factory--had to prepare a recommendation for the senior leadership of X regarding the future of Foghorn, a project she was leading to develop a carbon-neutral process for...
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Keywords:
Innovation;
R&D Project Management;
Radical Innovation;
Clean Technology;
Innovation and Management;
Technological Innovation;
Energy;
Research and Development;
Projects;
Management;
Decision Choices and Conditions;
Technology Industry;
Energy Industry;
Green Technology Industry;
California
Huckman, Robert S., Karim R. Lakhani, and Kyle R. Myers. "X: The Foghorn Decision." Harvard Business School Case 618-060, March 2018.
- January 2018
- Case
Flying into the Future: HondaJet
By: Gary P. Pisano and Jesse Shulman
This cases examine Honda’s diversification into the light jet market. In 1985, Honda initiated a secret program to develop a small jet. Over the years, the program had many ups and downs (it was almost canceled several times). Then, a breakthrough in the configuration...
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Keywords:
Diversification;
Technological Innovation;
Growth and Development Strategy;
Innovation and Management;
Air Transportation Industry
Pisano, Gary P., and Jesse Shulman. "Flying into the Future: HondaJet." Harvard Business School Case 618-012, January 2018.
- Article
The Board's New Innovation Imperative: Directors Need to Rethink Their Roles and Their Attitude to Risk
By: Linda A. Hill and George Davis
As firms scramble for competitive advantage, boards—once the cautious voices urging management to mitigate risk—are now calling for breakthrough innovation. Indeed, avoiding risk is now seen as the riskiest proposition of all. In speaking with CEOs and board members...
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Keywords:
Governing and Advisory Boards;
Innovation Leadership;
Risk and Uncertainty;
Corporate Governance
Hill, Linda A., and George Davis. "The Board's New Innovation Imperative: Directors Need to Rethink Their Roles and Their Attitude to Risk." Harvard Business Review 95, no. 6 (November–December 2017): 102–109.
- May 2017 (Revised October 2017)
- Case
Hyperloop Transportation Technologies: Building Breakthrough Innovations in Crowd-Powered Ecosystems
By: Lynda M. Applegate, Terri L. Griffith and Ann Majchrzak
Dirk Ahlborn, co-founder and CEO of Hyperloop Transportation Technologies, Inc. (HTT) looks back at the evolving organizational design and community that allows HTT to be crowd-powered. Since the founding in 2013, HTT has dealt with building an organization with less...
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Keywords:
Collaboration;
Crowdsourcing;
Entrepreneurial Finance;
Innovation;
Organizational Design;
Startups;
Business Startups;
Collaborative Innovation and Invention;
Entrepreneurship;
Finance;
Product Development
Applegate, Lynda M., Terri L. Griffith, and Ann Majchrzak. "Hyperloop Transportation Technologies: Building Breakthrough Innovations in Crowd-Powered Ecosystems." Harvard Business School Case 817-134, May 2017. (Revised October 2017.)
- 2017
- Chapter
Entrepreneurship in Larger Companies
By: William R. Kerr
Entrepreneurship in large and established companies is vital for their long-term success. Incumbent firms face many challenges ranging from global competition to digitization. In times past, being caught flat-footed might have set a company back several years, but it...
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Keywords:
Corporate Entrepreneurship
Kerr, William R. "Entrepreneurship in Larger Companies." Chap. 27 in The Entrepreneur's Roadmap: From Concept to IPO, edited by Tim Dempsey and Bonnie Hyun, 161–164. Chicago, IL: Caxton Business & Legal, Inc., 2017.
- December 2016
- Background Note
Reaching Beyond Your Organization: Empowering Innovation
By: William R. Kerr
Forward-thinking established companies utilize new routes for external innovation with start-ups and crowds. The reading reviews strategic partnerships, strategic investments, strategic acquisitions, and crowd-based collaborations. Case examples include Google, SK...
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Keywords:
Innovation;
Corporate Innovation;
Collaboration;
Partnerships;
Innovation and Invention;
Collaborative Innovation and Invention;
Innovation Strategy
Kerr, William R. "Reaching Beyond Your Organization: Empowering Innovation." Harvard Business School Background Note 817-044, December 2016.
- November 2016 (Revised April 2018)
- Case
reMarkable: e-Writing the Future
By: Elie Ofek and Curtis Hsu
Magnus Wanberg is the creator of reMarkable, a breakthrough e-writer device set apart from similar products on the market by having solved the frustrating “slow ink” problem typically experienced on pen-based electronic devices, thus providing a “pen and paper” like...
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Keywords:
Entrepreneurial Marketing;
Innovation Management;
Go To Market Strategy;
Marketing Plan;
Target Market;
Digital Devices;
Consumer Electronics;
Forecasting;
Information Technology;
Marketing Strategy;
Innovation and Management;
Marketing Channels;
Entrepreneurship;
Forecasting and Prediction;
Product Marketing;
Product Development;
Electronics Industry
Ofek, Elie, and Curtis Hsu. "reMarkable: e-Writing the Future." Harvard Business School Case 517-018, November 2016. (Revised April 2018.)