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  • October 2012
  • Case

GSK's Acquisition of Sirtris: Independence or Integration? (Abridged)
By: Toby Stuart and James Weber
An executive from pharmaceutical company GSK must choose how much to integrate a recently acquired biotechnology firm, Sirtris. Moncef Slaoui, GSK's global head of R&D, championed the acquisition of Sirtris to gain access to its potentially revolutionary science....  View Details
Keywords: Mergers and Acquisitions; Resource Allocation; Organizational Change and Adaptation; Organizational Culture; Organizational Structure; Research and Development; Science-Based Business; Integration
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  • October 2012
  • Case

Sirtris Pharmaceuticals: Living Healthier, Longer (Abridged)
By: Toby Stuart and James Weber
Describes a set of key strategic decisions facing the scientific founder and CEO of a promising, early stage bio-pharmaceuticals company. Should the company establish a proposed alliance with a pharmaceutical firm? Should it create a nutraceuticals business in parallel...  View Details
Keywords: Business Startups; Decision Choices and Conditions; Entrepreneurship; Growth and Development Strategy; Risk Management; Brands and Branding; Pharmaceutical Industry
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  • 2011
  • Working Paper

Discretion Within the Constraints of Opportunity: Gender Homophily and Structure in a Formal Organization
By: Adam M. Kleinbaum, Toby E. Stuart and Michael L. Tushman
Homophily in social relations is widely documented. We know that homophily results from both individual preferences and uneven opportunities for interaction, but how these two mechanisms interact in formal organizations is not well understood. We argue that...  View Details
Keywords: Interactive Communication; Analytics and Data Science; Organizational Structure; Partners and Partnerships; Behavior; Internet and the Web; Theory; Information Technology Industry
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  • 2011
  • Working Paper

Inside the Black Box of the Corporate Staff: An Exploratory Analysis Through the Lens of E-Mail Networks
By: Toby E. Stuart
The corporate staff is central in theories of the multi-business firm, but empirical evidence on its function is limited. In this paper, we examine the high-level role of two units of a corporate staff through analysis of electronic communications. We find sharp...  View Details
Keywords: Theory; Business Ventures; Internet and the Web; Communication; Employment; Management Teams; Networks
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  • 2011
  • Working Paper

Matthew: Effect or Fable?
By: Toby E. Stuart
In a market context, a status effect occurs when actors are accorded differential recognition for their efforts depending on their location in a status ordering, holding constant the quality of these efforts. In practice, because it is very difficult to measure...  View Details
Keywords: Risk and Uncertainty; Status and Position; Measurement and Metrics; Quality
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  • 2010
  • Working Paper

Boundary Spanning in a For-profit Research Lab: An Exploration of the Interface Between Commerce and Academe
By: Christopher C. Liu and Toby E. Stuart
In innovative industries, private-sector companies increasingly are participants in open communities of science and technology. To participate in the system of exchange in such communities, firms often publicly disclose what would otherwise remain private discoveries....  View Details
Keywords: For-Profit Firms; Higher Education; Information Publishing; Innovation and Invention; Science-Based Business; Social and Collaborative Networks; Boundaries; Biotechnology Industry; Pharmaceutical Industry
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  • 2010
  • Working Paper

From Bench to Board: Gender Differences in University Scientists' Participation in Commercial Science
By: Toby E. Stuart
This paper examines gender differences in the participation of university life science faculty in commercial science. Based on theory and field interviews, we develop hypotheses regarding how scientists' productivity, co-authorship networks, and institutional...  View Details
Keywords: Business Startups; For-Profit Firms; Gender Characteristics; Higher Education; Entrepreneurship; Governing and Advisory Boards; Science-Based Business; Nonprofit Organizations; Biotechnology Industry
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  • July 2010
  • Article

Board Interlocks and the Propensity to Be Targeted in Private Equity Transactions
By: Toby E. Stuart and Soojin Yim
In this paper, we examine the propensity for U.S. public companies to become targets for private equity-backed, take-private transactions. We consider the characteristics of 483 private equity-backed deals in the 2000-2007 period relative to public companies, and find...  View Details
Keywords: Board Interlocks; Board Networks; Social Networks; Private Equity; Corporate Governance; Public Ownership; Market Transactions; Governing and Advisory Boards; United States
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  • June 2010 (Revised August 2011)
  • Case

Tennant Company: Innovating Within and Beyond the Core
By: Lynda M. Applegate, Toby E. Stuart and James Weber
Tennant, a leading producer of floor cleaning equipment, must determine the business model to use for its new chemical-free cleaning technology. In 2005, Tennant Company had developed an innovative, environmentally friendly cleaning technology that could potentially...  View Details
Keywords: Business Model; Business Startups; Corporate Entrepreneurship; Disruptive Innovation; Organizational Structure; Business Strategy; Value Creation; Consumer Products Industry; Industrial Products Industry
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  • April 2010
  • Case

Talent Agencies
By: Thomas R. Eisenmann, Toby E. Stuart and Lauren Barley
The case overviews the talent agency industry in Hollywood in 2009. Focuses on the role of the talent agent, the dynamics of professional service firms, the challenges facing agencies in light of major changes in the entertainment industries, and a possible merger...  View Details
Keywords: Mergers and Acquisitions; Problems and Challenges; Change; Entertainment and Recreation Industry; Los Angeles
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  • April 2010
  • Case

Manchester Bidwell Corporation: the Replication Question
By: Toby E. Stuart, G. Felda Hardymon, James L. Heskett and Ann Leamon
Bill Strickland, CEO of Manchester Bidwell Corporation, must decide the best way to replicate his innovative, award-winning approach to curing poverty. Manchester Bidwell's approach, which provides both adult job-training tuned to fill the needs of local industries and...  View Details
Keywords: Corporate Entrepreneurship; Nonprofit Organizations; Growth and Development; Social Enterprise; Poverty; Training; Competency and Skills; Jobs and Positions; Human Resources
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  • March 2010 (Revised October 2010)
  • Case

The Huffington Post
By: Thomas R. Eisenmann, Toby E. Stuart and David Kiron
In Feb. 2010, management of the Huffington Post, a fast-growing but not-yet-profitable Internet newspaper that aggregates blog posts from unpaid contributors and excerpts of stories originally published by other news sites, faces a number of decisions about its growth...  View Details
Keywords: Networks; Business Model; Cost vs Benefits; Internet and the Web; Entrepreneurship; Growth and Development Strategy; Publishing Industry; Media and Broadcasting Industry
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  • February 2010 (Revised January 2014)
  • Case

Tennant Company
By: Toby E. Stuart, Lynda M. Applegate and James Weber
Tennant, a leading producer of floor cleaning equipment, must determine how to create, finance, structure, staff, govern, measure, and manage a new venture for developing a fundamentally new product line. In 2005, Tennant Company had developed an innovative,...  View Details
Keywords: Business Startups; Change Management; Corporate Entrepreneurship; Disruptive Innovation; Product Development; Organizational Design; Organizational Structure; Research and Development
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  • 2009
  • Working Paper

Social Influence Given (Partially) Deliberate Matching: Career Imprints in the Creation of Academic Entrepreneurs
By: Pierre Azoulay, Christopher C. Liu and Toby E. Stuart
Actors often match with associates on a small set of dimensions that matter most for the particular relationship at hand. In so doing, they are exposed to unanticipated social influences because counterparts have more interests, attitudes, and preferences than would-be...  View Details
Keywords: Entrepreneurship; Patents; Marketplace Matching; Mathematical Methods; Science-Based Business; Power and Influence; Social and Collaborative Networks; Biotechnology Industry
Related
  • April 2009
  • Case

GSK's Acquisition of Sirtris: Independence or Integration?
By: Toby E. Stuart and James Weber
An executive from pharmaceutical company GSK must choose how much to integrate a recently acquired biotechnology firm, Sirtris. Moncef Slaoui, GSK's global head of R&D, championed the acquisition of Sirtris to gain access to its potentially revolutionary science....  View Details
Keywords: Mergers and Acquisitions; Resource Allocation; Organizational Change and Adaptation; Organizational Culture; Organizational Structure; Research and Development; Science-Based Business; Integration
Related
  • March 2009
  • Case

Incept LLC and Confluent Surgical (A)
By: Bhaskar Chakravorti, Toby E. Stuart and James Weber
A venture capitalist must decide whether to invest in a medical technology company that licenses intellectual property from a privately held IP holding company based on a platform technology. Entrepreneurs Amar Sawhney and Fred Khosravi founded Incept LLC to...  View Details
Keywords: Business Model; Entrepreneurship; Intellectual Property; Rights; Agreements and Arrangements; Partners and Partnerships; Trust; Medical Devices and Supplies Industry
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  • March 2009 (Revised July 2009)
  • Case

KiOR: Catalyzing Clean Energy
By: Ramana Nanda and Toby E. Stuart
Biofuels start-up KiOR was developing a proprietary technology that had the potential to dramatically impact the emerging renewable energy landscape: a process that converted cellulosic biomass into "bio-crude," a hydrocarbon mixture with properties to those of crude...  View Details
Keywords: Business Headquarters; Decision Choices and Conditions; Renewable Energy; Entrepreneurship; Geographic Location
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  • February 2009 (Revised May 2010)
  • Case

Orange: Read&Go
By: Thomas R. Eisenmann, Toby E. Stuart, Bhaskar Chakravorti, Vincent Marie Dessain, Simon Harrow and Elena Corsi
In late 2008, Orange (aka France Telecom) must decide if launching Read&Go, an electronic newsstand built around an e-paper reader, would be successful. The case describes (1) Orange's strategy; (2) the company's new product development process; (3) e-paper technology,...  View Details
Keywords: Business Model; Corporate Entrepreneurship; Technological Innovation; Demand and Consumers; Product Development; Partners and Partnerships; Competition; Publishing Industry; France
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  • January 2009
  • Supplement

Yieldex (B)
By: Toby E. Stuart
Yieldex CEO Tom Shields was hired by the company's technical founder, Doug Cosman, in October 2007. One of Shields' top priorities is finding a vice president of engineering to manage the company's software development efforts. Shields and Costman disagree about the...  View Details
Keywords: Selection and Staffing; Applications and Software; Engineering; Decision Choices and Conditions; Product Development; Information Technology Industry
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  • 2008
  • Working Paper

Communication (and Coordination?) in a Modern, Complex Organization
By: Adam M. Kleinbaum, Toby E. Stuart and Michael L. Tushman
This is a descriptive study of the structure of communications in a modern organization. We analyze a dataset with millions of electronic mail messages, calendar meetings and teleconferences for many thousands of employees of a single, multidivisional firm during a...  View Details
Keywords: Business Conglomerates; Interpersonal Communication; Organizational Structure; Social Issues; Boundaries
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