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- March 2025 (Revised May 2025)
- Case
NEAR Protocol: Self-Sovereignty in the Age of AI
By: Shikhar Ghosh, Liang Wu and Mahesh Ramakrishnan
Ghosh, Shikhar, Liang Wu, and Mahesh Ramakrishnan. "NEAR Protocol: Self-Sovereignty in the Age of AI." Harvard Business School Case 825-115, March 2025. (Revised May 2025.)
- March 2025
- Case
Metaphysic AI: Rethinking the Value of Human Expertise
By: Zoë B. Cullen, Shikhar Ghosh and Shweta Bagai
In early 2025, Thomas Graham, CEO of Metaphysic, a leading AI generative video company confronted fundamental questions about who should control digital identity in a world where AI could perfectly recreate human likeness. Founded in 2021, Metaphysic first rose to fame... View Details
Keywords: Business Model; Ethics; AI and Machine Learning; Intellectual Property; Rights; Negotiation; Value; Motion Pictures and Video Industry; Technology Industry
Cullen, Zoë B., Shikhar Ghosh, and Shweta Bagai. "Metaphysic AI: Rethinking the Value of Human Expertise." Harvard Business School Case 825-146, March 2025.
- December 2024
- Case
Blue Cross Blue Shield of Michigan (BCBSM): The AI Journey
By: Shikhar Ghosh
In early 2024, Bill Fandrich, Executive VP and CIO of Blue Cross Blue Shield of Michigan (BCBSM), faced a critical decision about AI adoption within the organization. Fandrich had championed AI implementation at BCBSM. After successfully developing three AI... View Details
Keywords: Blue Cross; Automation; Generative Ai; Health Insurance; Insurance Companies; Innovation; IT Strategy; Organizational Transformations; Technology; Non-profit; AI and Machine Learning; Health; Digital Strategy; Digital Transformation; Leadership; Technology Adoption; Job Cuts and Outsourcing; Innovation Strategy; Health Industry; Insurance Industry; Michigan
Ghosh, Shikhar. "Blue Cross Blue Shield of Michigan (BCBSM): The AI Journey." Harvard Business School Case 825-082, December 2024.
- November 2024
- Case
AlphaGo (A): Birth of a New Intelligence
By: Shikhar Ghosh and Shweta Bagai
This case, the first of a three-part series, traces DeepMind's evolution from its 2010 founding through its acquisition by Google in 2014. Often referred to as the "Apollo project" of artificial intelligence, DeepMind used games as a testing ground to develop AI... View Details
Keywords: AI and Machine Learning; Technology Adoption; Games, Gaming, and Gambling; Technological Innovation; Creativity; Technology Industry; South Korea; China; United States
Ghosh, Shikhar, and Shweta Bagai. "AlphaGo (A): Birth of a New Intelligence." Harvard Business School Case 825-073, November 2024.
- November 2024
- Supplement
AlphaGo (B): Birth of a New Intelligence
By: Shikhar Ghosh and Shweta Bagai
This case, the second in a three-part series, explores DeepMind's evolution from developing game-specific AI to more generalized learning systems. Following AlphaGo's 2017 victory over the Go world champion, DeepMind introduced two revolutionary systems that eliminated... View Details
Keywords: AI and Machine Learning; Games, Gaming, and Gambling; Technological Innovation; Disruptive Innovation; Innovation Leadership; Information Technology Industry; United States; Russia; China
Ghosh, Shikhar, and Shweta Bagai. "AlphaGo (B): Birth of a New Intelligence." Harvard Business School Supplement 825-074, November 2024.
- November 2024
- Supplement
AlphaGo (C): Birth of a New Intelligence
By: Shikhar Ghosh and Shweta Bagai
This case, the final of a three-part series, explores DeepMind's pivotal transition from mastering games to solving real-world scientific challenges. In December 2020, DeepMind's AI system AlphaFold 2 achieved a breakthrough by solving protein folding—a 50-year-old... View Details
Keywords: Autonomy; Deep Learning; Drug Discovery; Healthcare Innovation; Neural Networks; Scientific Research; Technology Startup; AI and Machine Learning; Technological Innovation; Research and Development; Business Model; Business Strategy; Open Source Distribution; Technology Industry; United States
Ghosh, Shikhar, and Shweta Bagai. "AlphaGo (C): Birth of a New Intelligence." Harvard Business School Supplement 825-075, November 2024.
- November 2024 (Revised January 2025)
- Case
MiDAS: Automating Unemployment Benefits
By: Shikhar Ghosh and Shweta Bagai
In 2015, the state of Michigan considered whether to nominate its Michigan Integrated Data Automated System (MiDAS) for a prestigious state technology award. Launched in 2013 amid severe budget pressures, the $47 million automated fraud detection system was designed to... View Details
Keywords: Artificial Intelligence; AI; Machine Learning Models; Algorithmic Data; Automation; Benefits; Compensation; Cost Reduction; Government; Fraud; Government Technology; Public Sector; Systems; Systems Integration; Unemployment Insurance; Waste Heat Recovery; AI and Machine Learning; Government Administration; Insurance; Decision Making; Digital Transformation; Employment; Public Administration Industry; United States; Michigan
Ghosh, Shikhar, and Shweta Bagai. "MiDAS: Automating Unemployment Benefits." Harvard Business School Case 825-100, November 2024. (Revised January 2025.)
- August 2024
- Case
Circle: Reinventing the Future of Money
By: Shikhar Ghosh and Shweta Bagai
In early 2024, Circle Internet Financial's leadership team gathered to discuss the company's strategic path as it prepared for an IPO. Founded in 2013 by Jeremy Allaire, Circle had emerged as a pioneer in digital finance through its USD Coin (USDC), a regulated... View Details
Keywords: Currency; Governance Compliance; Initial Public Offering; Competition; Financial Services Industry
Ghosh, Shikhar, and Shweta Bagai. "Circle: Reinventing the Future of Money." Harvard Business School Case 825-067, August 2024.
- July 2024
- Case
Replika AI: Alleviating Loneliness (A)
By: Shikhar Ghosh and Shweta Bagai
Eugenia Kuyda launched Replika AI in 2017 as an empathetic digital companion to combat loneliness and provide emotional support. The platform surged in popularity during the COVID-19 pandemic, offering non-judgmental support to isolated users. By 2023, Replika boasted... View Details
Keywords: Entrepreneurship; Ethics; Health Pandemics; AI and Machine Learning; Well-being; Technology Industry
Ghosh, Shikhar, and Shweta Bagai. "Replika AI: Alleviating Loneliness (A)." Harvard Business School Case 824-088, July 2024.
- June 2024
- Case
Alignvest Student Housing: Keep Building or Time to Sell?
By: Shikhar Ghosh and Patrick Sanguineti
Sanjil Shah, Managing Partner of Alignvest Student Housing REIT (ASH), faces the most significant decision thus far in his career: is it the right time to sell the company? Together with his partner Reza Satchu, Shah had developed ASH into the largest student housing... View Details
Keywords: Exit Strategy; Real Estate; Founder; Equity Valuation; Decisions; Entrepreneurial Finance; Interest Rates; Health Pandemics; Housing; Partners and Partnerships; Expansion; Entrepreneurship; Business Exit or Shutdown; Canada
Ghosh, Shikhar, and Patrick Sanguineti. "Alignvest Student Housing: Keep Building or Time to Sell?" Harvard Business School Case 824-208, June 2024.
- June 2024 (Revised August 2024)
- Technical Note
Web3 Business Model Design for Entrepreneurs
By: Shikhar Ghosh and Liang Wu
Ghosh, Shikhar, and Liang Wu. "Web3 Business Model Design for Entrepreneurs." Harvard Business School Technical Note 824-177, June 2024. (Revised August 2024.)
- April 2024 (Revised December 2024)
- Case
Anthropic: Building Safe AI
By: Shikhar Ghosh and Shweta Bagai
In late 2024, Anthropic, a leading AI safety and research company, achieved a significant breakthrough with computer use capabilities that allowed AI to interact with computers like humans. Co-founded by former OpenAI employees and known for its generative AI... View Details
Keywords: AI and Machine Learning; Corporate Accountability; Corporate Social Responsibility and Impact; Business Growth and Maturation; Corporate Strategy; Technology Industry; United States
Ghosh, Shikhar, and Shweta Bagai. "Anthropic: Building Safe AI." Harvard Business School Case 824-129, April 2024. (Revised December 2024.)
- February 2024 (Revised April 2024)
- Case
Uniswap: Fighting a Vampire Attack (A)
By: Shikhar Ghosh, Shweta Bagai and Liang Wu
This is the first of a three-case series that explores the challenges faced by Uniswap, a key player in the decentralized finance (DeFi) sector. Founded by Hayden Adams, the case traces Uniswap's rapid growth from a simple idea inspired by a Reddit post to becoming one... View Details
Keywords: Blockchain; Cryptocurrency; Crypto Economy; Community; Decentralization; Decentralized Exchange; Decentralized Finance; Open Platforms; Open-source Innovation; Market Distruption; Stablecoin; Vampire Attack; Web3; Token; Digital Platforms; Entrepreneurship; Governance; Technological Innovation; Competitive Strategy; Financial Liquidity; Financial Services Industry; Technology Industry; United States
Ghosh, Shikhar, Shweta Bagai, and Liang Wu. "Uniswap: Fighting a Vampire Attack (A)." Harvard Business School Case 824-162, February 2024. (Revised April 2024.)
- February 2024 (Revised April 2024)
- Supplement
Uniswap: Fighting a Vampire Attack (B)
By: Shikhar Ghosh, Shweta Bagai and Liang Wu
Ghosh, Shikhar, Shweta Bagai, and Liang Wu. "Uniswap: Fighting a Vampire Attack (B)." Harvard Business School Supplement 824-163, February 2024. (Revised April 2024.)
- February 2024 (Revised April 2024)
- Supplement
Uniswap: Fighting a Vampire Attack (C)
By: Shikhar Ghosh, Shweta Bagai and Liang Wu
Ghosh, Shikhar, Shweta Bagai, and Liang Wu. "Uniswap: Fighting a Vampire Attack (C)." Harvard Business School Supplement 824-164, February 2024. (Revised April 2024.)
- January 2024 (Revised April 2024)
- Case
Target Malaria: Editing Mosquitoes through Gene Drives
By: Shikhar Ghosh and Shweta Bagai
Target Malaria, a non-profit research consortium, is exploring the application of CRISPR-Cas9 gene editing technology to combat malaria in Sub-Saharan Africa. Its approach uses gene drives, a revolutionary tool, to suppress the population of malaria-carrying... View Details
Keywords: Health Disorders; Technological Innovation; Nonprofit Organizations; Business Strategy; Genetics; Ethics; Governing Rules, Regulations, and Reforms; United States; United Kingdom; Burkina Faso; Africa
Ghosh, Shikhar, and Shweta Bagai. "Target Malaria: Editing Mosquitoes through Gene Drives." Harvard Business School Case 824-068, January 2024. (Revised April 2024.)
- January 2024 (Revised February 2024)
- Case
OpenAI: Idealism Meets Capitalism
By: Shikhar Ghosh and Shweta Bagai
In November 2023, the board of OpenAI, one of the most successful companies in the history of technology, decided to fire Sam Altman, its charismatic and influential CEO. Their decision shocked the corporate world and had people wondering why OpenAI had designed a... View Details
Keywords: AI; AI and Machine Learning; Governing and Advisory Boards; Ethics; Strategy; Technological Innovation; Leadership
Ghosh, Shikhar, and Shweta Bagai. "OpenAI: Idealism Meets Capitalism." Harvard Business School Case 824-134, January 2024. (Revised February 2024.)
- December 2023
- Case
TikTok: The Algorithm Will See You Now
By: Shikhar Ghosh and Shweta Bagai
In a world where attention is a scarce commodity, this case explores the meteoric rise of TikTok—an app that transformed from a niche platform for teens into the most visited domain by 2021—surpassing even Google. Its algorithm was a sophisticated mechanism for... View Details
Keywords: Social Media; Applications and Software; Disruptive Innovation; Business and Government Relations; International Relations; Cybersecurity; Culture; Technology Industry; China; United States; India
Ghosh, Shikhar, and Shweta Bagai. "TikTok: The Algorithm Will See You Now." Harvard Business School Case 824-125, December 2023.