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Publications

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    • Faculty Publications  (26)

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    • All HBS Web  (109,080)
      • Faculty Publications  (26)

      Krieger, Joshua Lev Remove Krieger, Joshua Lev →

      Page 1 of 26 Results →
      • September 2022
      • Article

      Find and Replace: R&D Investment Following the Erosion of Existing Products

      By: Joshua L. Krieger, Xuelin Li and Richard T. Thakor
      How do innovative firms react when existing products experience negative shocks? We explore this question with detailed project-level data from drug development firms. Using FDA Public Health Advisories as idiosyncratic negative shocks to approved drugs, we first...  View Details
      Keywords: R&D Investments; Drug Development; Product Shocks; M&A; Biopharmaceutical Industry; FDA; System Shocks; Research and Development; Investment; Decision Making; Pharmaceutical Industry
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      Krieger, Joshua L., Xuelin Li, and Richard T. Thakor. "Find and Replace: R&D Investment Following the Erosion of Existing Products." Management Science 68, no. 9 (September 2022): 6552–6571.
      • 2022
      • Working Paper

      Are Transformational Ideas Harder to Fund? Resource Allocation to R&D Projects at a Global Pharmaceutical Firm

      By: Joshua Krieger and Ramana Nanda
      We study resource allocation to early-stage ideas at an internal startup program of one the largest pharmaceutical firms in the world. Our research design enables us to elicit every evaluator's scores across five different attributes, before seeing how would allocate...  View Details
      Keywords: Project Selection; Pharmaceuticals; Financing Innovation; Resource Allocation; Innovation and Invention; Research and Development
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      Krieger, Joshua, and Ramana Nanda. "Are Transformational Ideas Harder to Fund? Resource Allocation to R&D Projects at a Global Pharmaceutical Firm." Harvard Business School Working Paper, No. 23-014, August 2022.
      • August 2022
      • Teaching Note

      AppHarvest: Rebuilding the Appalachian Economy Through Agriculture

      By: Joshua Lev Krieger, William R. Kerr and Bailey McAfee
      Keywords: Agriculture; Entrepreneurship; Agriculture and Agribusiness Industry
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      Krieger, Joshua Lev, William R. Kerr, and Bailey McAfee. "AppHarvest: Rebuilding the Appalachian Economy Through Agriculture." Harvard Business School Teaching Note 823-024, August 2022.
      • August 2022
      • Teaching Note

      In-Q-Tel: Innovation On A Mission

      By: Josh Lerner and Joshua Lev Krieger
      Teaching Note for HBS Case No. 823-031.  View Details
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      Lerner, Josh, and Joshua Lev Krieger. "In-Q-Tel: Innovation On A Mission." Harvard Business School Teaching Note 823-042, August 2022.
      • August 2022
      • Case

      In-Q-Tel: Innovation On A Mission

      By: Joshua Lev Krieger and Josh Lerner
      In 2022, the leaders of In-Q-Tel (IQT) considered what was next for the unique mission-driven organization. Since 1999, IQT had one mission: to be the most sophisticated source of strategic technical knowledge and capabilities to the U.S. government and its allies. IQT...  View Details
      Keywords: Mission and Purpose; National Security; Technological Innovation; Research; Geopolitical Units; Risk Management; Recruitment; Growth and Development Strategy; Venture Capital; Knowledge Management; Information Industry; Banking Industry
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      Krieger, Joshua Lev, and Josh Lerner. "In-Q-Tel: Innovation On A Mission." Harvard Business School Case 823-031, August 2022.
      • March 2022
      • Teaching Note

      Tomorrow.io Goes To Space

      By: Joshua Lev Krieger, Abhishek Nagaraj and James Barnett
      Teaching Note for HBS Case No. 822-005. In March 2021, the weather company Tomorrow.io announced a new project to develop satellites equipped with radar for weather monitoring and launch them into Earth’s orbit. Company leadership considers execution strategies.  View Details
      Keywords: Communication; Competency and Skills; Decision Making; Design; Engineering; Globalization; Innovation and Invention; Performance; Technological Innovation; Aerospace Industry
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      Krieger, Joshua Lev, Abhishek Nagaraj, and James Barnett. "Tomorrow.io Goes To Space." Harvard Business School Teaching Note 822-102, March 2022.
      • March 2022
      • Teaching Note

      Biobot Analytics

      By: Ray Kluender, Joshua Krieger and Mitch Weiss
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      Kluender, Ray, Joshua Krieger, and Mitch Weiss. "Biobot Analytics." Harvard Business School Teaching Note 822-079, March 2022.
      • 2022
      • Article

      Missing Novelty in Drug Development

      By: Joshua Krieger, Danielle Li and Dimitris Papanikolaou
      We provide evidence that risk aversion leads pharmaceutical firms to underinvest in radical innovation. We introduce a new measure of drug novelty based on chemical similarity and show that firms face a risk-reward trade-off: novel drug candidates are less likely to...  View Details
      Keywords: Drug Development; Risk Aversion; Research and Development; Innovation and Invention; Investment; Pharmaceutical Industry
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      Krieger, Joshua, Danielle Li, and Dimitris Papanikolaou. "Missing Novelty in Drug Development." Review of Financial Studies 35, no. 2 (February 2022): 636–679.
      • January 2022
      • Case

      Tomorrow.io Goes To Space

      By: Joshua Lev Krieger, Abhishek Nagaraj and James Barnett
      In March 2021, the weather company Tomorrow.io announced a new project to develop satellites equipped with radar for weather monitoring and launch them into Earth’s orbit. Company leadership considers execution strategies.  View Details
      Keywords: Communication; Competency and Skills; Engineering; Globalization; Innovation and Invention; Performance; Technology; Aerospace Industry
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      Krieger, Joshua Lev, Abhishek Nagaraj, and James Barnett. "Tomorrow.io Goes To Space." Harvard Business School Case 822-005, January 2022.
      • January 2022 (Revised March 2022)
      • Teaching Note

      Catalys Pacific

      By: Joshua Lev Krieger
      Teaching Note for HBS Case No. 821-035.  View Details
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      Krieger, Joshua Lev. "Catalys Pacific." Harvard Business School Teaching Note 822-086, January 2022. (Revised March 2022.)
      • November 2021 (Revised March 2022)
      • Case

      AppHarvest: Rebuilding the Appalachian Economy Through Agriculture

      By: Joshua Lev Krieger, William R. Kerr and Christian Godwin
      In 2021, AppHarvest completed construction of a 60-acre indoor farming facility, one of the world’s largest, recorded its first sales, and went public in a multi-billion dollar IPO. Described as “a force of nature,” Jonathan Webb founded the company to bring jobs back...  View Details
      Keywords: Agricultural; Entrepreneur; Business Startups; Development Economics; Sales; Goals and Objectives; Going Public; Growth Management; Buildings and Facilities; Agriculture and Agribusiness Industry; North America
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      Krieger, Joshua Lev, William R. Kerr, and Christian Godwin. "AppHarvest: Rebuilding the Appalachian Economy Through Agriculture." Harvard Business School Case 822-067, November 2021. (Revised March 2022.)
      • 2023
      • Working Paper

      How Important Is Editorial Gatekeeping? Evidence from Top Biomedical Journals

      By: Joshua L. Krieger, Kyle R. Myers and Ariel D. Stern
      We examine editors’ influence on the scientific content of academic journals by unpacking the role of three major forces: journals’ stated missions, the aggregate supply of and demand for specific topics, and scientific homophily via editorial gatekeeping. In...  View Details
      Keywords: Jobs and Positions; Operations; Information Publishing; Analysis
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      Krieger, Joshua L., Kyle R. Myers, and Ariel D. Stern. "How Important Is Editorial Gatekeeping? Evidence from Top Biomedical Journals." Harvard Business School Working Paper, No. 22-011, September 2021. (Revised January 2023. Accepted at Review of Economics and Statistics.)
      • September 2021
      • Article

      Trials and Terminations: Learning from Competitors' R&D Failures

      By: Joshua L. Krieger
      I analyze project continuation decisions where firms may resolve uncertainty through news about competitors' research and development (R&D) failures, as well as through their own results. I examine the trade-offs and interactions between product-market competition and...  View Details
      Keywords: Research and Development; Projects; Failure; Decision Making; Learning
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      Krieger, Joshua L. "Trials and Terminations: Learning from Competitors' R&D Failures." Management Science 67, no. 9 (September 2021).
      • 2022
      • Working Paper

      Standing on the Shoulders of Science

      By: Joshua Lev Krieger, Monika Schnitzer and Martin Watzinger
      Today's innovations rely on scientific discoveries of the past, yet only some corporate R&D builds directly on scientific output. In this paper, we analyze U.S. patents to investigate how firms generate value by building on prior art "closer" to science and establish...  View Details
      Keywords: Patent Novelty; Value Capture; Science; Patents; Valuation; Research and Development
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      Krieger, Joshua Lev, Monika Schnitzer, and Martin Watzinger. "Standing on the Shoulders of Science." Harvard Business School Working Paper, No. 21-128, June 2021. (Revised September 2022.)
      • May 2021
      • Article

      Private and Social Returns to R&D: Drug Development and Demographics

      By: Efraim Benmelech, Janice Eberly, Dimitris Papanikolaou and Joshua Krieger
      Investment in intangible capital such as R&D has increased dramatically since the 1990s. However, productivity growth remains sluggish in recent years. One potential reason is that a significant share of the increase in intangible investment is geared toward consumer...  View Details
      Keywords: Drug Development; Research and Development; Investment Return; Demographics; Pharmaceutical Industry
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      Benmelech, Efraim, Janice Eberly, Dimitris Papanikolaou, and Joshua Krieger. "Private and Social Returns to R&D: Drug Development and Demographics." AEA Papers and Proceedings 111 (May 2021): 336–340.
      • January 2021 (Revised December 2021)
      • Case

      Biobot Analytics

      By: Raymond Kluender, Joshua Krieger and Mitchell Weiss
      In 2017, Newsha Ghaeli and Mariana Matus were deciding whether to leave their labs at the Massachusetts Institute of Technology, put other job opportunities aside, and dive full-time into founding a wastewater analysis start-up, Biobot. Ghaeli, an architect, and Matus,...  View Details
      Keywords: Entrepreneurship; Information Technology; City; Analytics and Data Science; Personal Development and Career; Technology Industry; Utilities Industry; Health Industry; Information Technology Industry; Information Industry; Biotechnology Industry; United States; Kuwait; Korean Peninsula
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      Kluender, Raymond, Joshua Krieger, and Mitchell Weiss. "Biobot Analytics." Harvard Business School Case 821-045, January 2021. (Revised December 2021.)
      • December 2020 (Revised March 2022)
      • Teaching Note

      Forecasting ClimaCell

      By: Joshua Lev Krieger, Christopher Stanton and James Barnett
      A weather technology startup, ClimaCell considers the R&D trade-offs and financing implications of pursuing a proposed contract with a major automobile maker, rather than continuing its focus on building a scalable, all-purpose weather prediction engine.  View Details
      Keywords: Weather; Forecasting and Prediction; Business Startups; Research and Development; Finance; Cost vs Benefits; Decision Making; Strategy; United States; Israel; Massachusetts; Colorado
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      Krieger, Joshua Lev, Christopher Stanton, and James Barnett. "Forecasting ClimaCell." Harvard Business School Teaching Note 821-008, December 2020. (Revised March 2022.)
      • September 2020 (Revised January 2021)
      • Case

      Catalys Pacific

      By: Joshua Lev Krieger
      In 2019, BT Slingsby founds Catalys Pacific, the first biotech “venture creation” fund in Tokyo. After convincing some of the biggest Japanese pharmaceutical firms to invest, BT hopes the fund can make a big splash and transform biotechnology innovation in Japan. After...  View Details
      Keywords: Pharmaceutical Companies; Biotech; Health Care; Entrepreneur; Innovation; International Business; Entrepreneurial Finance; Entrepreneurship; Finance; Innovation Strategy; Venture Capital; Strategy; Cross-Cultural and Cross-Border Issues; Pharmaceutical Industry; Biotechnology Industry; Tokyo
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      Krieger, Joshua Lev. "Catalys Pacific." Harvard Business School Case 821-035, September 2020. (Revised January 2021.)
      • December 2019
      • Case

      Forecasting ClimaCell

      By: Joshua Lev Krieger, Christopher Stanton and James Barnett
      A weather technology startup, ClimaCell considers the R&D trade-offs and financing implications of pursuing a proposed contract with a major automobile maker, rather than continuing its focus on building a scalable, all-purpose weather prediction engine.  View Details
      Keywords: Weather; Forecasting and Prediction; Technological Innovation; Research and Development; Finance; Cost vs Benefits; Decision Making; Strategy
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      Krieger, Joshua Lev, Christopher Stanton, and James Barnett. "Forecasting ClimaCell." Harvard Business School Case 820-044, December 2019.
      • 2020
      • Working Paper

      Trials and Terminations: Learning from Competitors' R&D Failures

      By: Joshua L. Krieger
      I analyze project continuation decisions where firms may resolve uncertainty through news about competitors' research and development (R&D) failures, as well as through their own results. I examine the trade-offs and interactions between product-market competition and...  View Details
      Keywords: Research and Development; Projects; Failure; Decision Making; Learning
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      Krieger, Joshua L. "Trials and Terminations: Learning from Competitors' R&D Failures." Harvard Business School Working Paper, No. 18-043, November 2017. (Revised June 2020. Forthcoming in Management Science.)
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