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- June 2021
- Case
Who Lives & Who Dies: Expanded Access for Experimental Drugs at Chimerix (A)
By: Amitabh Chandra and Spencer Lee-Rey
- June 2021
- Supplement
Who Lives & Who Dies: Expanded Access for Experimental Drugs at Chimerix (B)
By: Amitabh Chandra and Spencer Lee-Rey
- 2021
- Working Paper
Regulatory Approval and Expanded Market Size
By: Benjamin Berger, Amitabh Chandra and Craig Garthwaite
Regulatory review of new medicines is often viewed as a hindrance to innovation by increasing the hurdle to bring products to market. However, a more complete accounting of regulation must also account for its potential market expanding effects through quality...
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- 2021
- Working Paper
The Great Unequalizer: Initial Health Effects of COVID-19 in the United States
By: Marcella Alsan, Amitabh Chandra and Kosali I. Simon
We measure inequities from the COVID-19 pandemic on mortality and hospitalizations in the United States during the early months of the outbreak. We discuss challenges in measuring health outcomes and health inequality, some of which are specific to COVID-19 and others...
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- May 2021
- Case
The SMA Foundation: Steering Therapeutic Research and Development in a Rare Disease
By: Amitabh Chandra, Spencer Lee-Rey and Caroline Marra
This case explores incentives for rare disease drug development by chronicling the role of the Spinal Muscular Atrophy (SMA) Foundation in forming strategic partnerships with the scientific research community and pharmaceutical developers to transform the trajectory...
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- 2021
- Working Paper
The Health Costs of Cost-Sharing
By: Amitabh Chandra, Evan Flack and Ziad Obermeyer
We use the design of Medicare’s prescription drug benefit program to demonstrate three facts about the health consequences of cost-sharing. First, we show that an as-if-random increase of 33.6% in out-of-pocket price (11.0 percentage points (p.p.) change in...
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- January 2021
- Case
Value-Based Insurance Design at Onex
By: Joshua Schwartzstein, Amitabh Chandra and Amram Migdal
The operating executives of Health and Benefits for Onex Partners, Megan Jackson Frye and Sam Camens, faced a challenge: Healthcare costs for employees of Onex’s portfolio companies were continuing to rise above the consumer price index, reflecting broader trends...
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Keywords:
Decision Making;
Cost vs Benefits;
Decision Choices and Conditions;
Decisions;
Finance;
Behavioral Finance;
Insurance;
Health;
Health Care and Treatment;
Human Resources;
Compensation and Benefits;
Markets;
Demand and Consumers;
Consumer Behavior;
Social Psychology;
Behavior;
Interests;
Motivation and Incentives;
Perception;
Health Industry;
Insurance Industry;
North America;
United States
- 2020
- Working Paper
Hospital Allocation and Racial Disparities in Health Care
By: Amitabh Chandra, Pragya Kakani and Adam Sacarny
We develop a simple framework to measure the role of hospital allocation in racial disparities in health care and use it to study Black and white Medicare patients who are treated for heart attacks—a condition where virtually everyone receives care, hospital care is...
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- October 2020 (Revised June 2021)
- Case
What Will Best Serve Humanity? Accelerating Uses for CRISPR at the Broad Institute
By: Amitabh Chandra, Matthew C. Weinzierl, Lisa Marrone and Spencer Lee-Rey
- October 8, 2020
- Article
What Values and Priorities Mean for Health Reform
By: Katherine Baicker and Amitabh Chandra
- September 2020 (Revised February 2021)
- Case
Pricing the Priceless: Covering Transformational Medicines at Harvard Pilgrim Health Plan
By: Amitabh Chandra and Sofia Guerra
- September 15, 2020
- Article
Moving the Financing of Graduate Medical Education Into the 21st Century
By: Justin A. Grischkan, Ari B. Friedman and Amitabh Chandra
- September 8, 2020
- Article
Allocation of COVID-19 Relief Funding to Disproportionately Black Counties
By: Pragya Kakani, Amitabh Chandra and Sendhil Mullainathan
This study describes correlations between the dollar amount of relief funding authorized by the US Congress to fund prevention, diagnosis, and treatment of coronavirus disease 2019 (COVID-19) and to reimburse health care entities for lost revenues, and county-level...
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- September–October 2020
- Article
The Past, Present, and (Near) Future of Gene Therapy and Gene Editing
By: Julia Pian, Amitabh Chandra and Ariel Dora Stern
Emerging gene therapy and gene-editing technologies will have a growing impact on patient lives and health-care delivery. We analyzed a decade of data on clinical trials and venture capital investments to understand the likely trajectory of genetically focused...
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- Article
Do We Spend Too Much on Health Care?
By: Katherine Baicker and Amitabh Chandra
Health system reforms—such as changes in insurance design, patient cost sharing, payment reform, or price regulation—should be judged by whether they move us toward higher-value use of resources, rather than by whether they reduce spending.
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- 2020
- Working Paper
What Can Economics Say About Alzheimer's Disease?
By: Amitabh Chandra, Courtney Coile and Corina Mommaerts
Alzheimer’s Disease (AD) affects one in ten people aged 65 or older and is the most expensive disease in the United States. We describe the central economic questions raised by AD. While there is overlap with the economics of aging, the defining features of the...
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- July 28, 2020
- Article
Economic Vulnerability of Households with Essential Workers
By: Grace McCormack, Christopher Avery, Ariella Kahn-Lang Spitzer and Amitabh Chandra
The label of “essential worker” reflects society’s needs but does not mean that society has compensated those workers for additional risks incurred on the job during the current pandemic. When an essential worker contracts severe acute respiratory syndrome coronavirus...
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- March 13, 2020
- Editorial
Scale the Price for a Coronavirus Vaccine by the Harm it Averts
By: Amitabh Chandra
- May 2020
- Article
Identifying Sources of Inefficiency in Health Care
By: Amitabh Chandra and Douglas O. Staiger
In medicine, the reasons for variation in treatment rates across hospitals serving similar patients are not well understood. Some interpret this variation as unwarranted and push standardization of care as a way of reducing allocative inefficiency. However, an...
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- April 2020
- Case
Ginkgo Bioworks: The Cell as a Factory
By: Paul A. Gompers, Amitabh Chandra and Matthew Wozny