The DI builds community and expertise around the digital transformation of the economy at HBS and beyond through curated content, facilitated exchange, and thought leadership.
America's infrastructure woes and how to fix them were front and center at the recent summit, America on the Move: Transportation and Infrastructure for the 21st Century, led by Rosabeth Moss Kanter.
April
20, 2018
|
12:35pm -
1:10pm
| Baker Library | Bloomberg Center 102
Organizer: Finance Unit, Harvard Economics Department
Seminar
| Finance/Economics Ph.D. Lunch Seminar
Anastassia Fedyk, Harvard University
Trading on Talent: Human Capital and Firm Performance
April
20, 2018
|
12:00pm -
12:35pm
| Baker Library | Bloomberg Center 102
| Open to public
Organizer: Finance Unit, Harvard Economics Department
Seminar
| Science-based Business Seminar
Andrew Lo, MIT, Sloan School
SBBI Seminar: "Can Financial Engineering Cure Cancer?: New Approaches to Funding Biomedical Innovation" (Paper co-written with Chi Heem Wong and Kien Wei Siah)
SUMMARY
Previous estimates of drug development success rates rely on relatively small samples from databases curated by the pharmaceutical industry and are subject to potential selection biases. Using a sample of 406 038 entries of clinical trial data for over 21 143 compounds from January 1, 2000 to October 31, 2015, we estimate aggregate clinical trial success rates and durations. We also compute disaggregated estimates across several trial features including disease type, clinical phase, industry or academic sponsor, biomarker presence, lead indication status, and time. In several cases, our results differ significantly in detail from widely cited statistics. For example, oncology has a 3.4% success rate in our sample vs. 5.1% in prior studies. However, after declining to 1.7% in 2012, this rate has improved to 2.5% and 8.3% in 2014 and 2015, respectively. In addition, trials that use biomarkers in patient-selection have higher overall success probabilities than trials without biomarkers.
April
20, 2018
|
12:00pm -
1:30pm
| Baker Library | Bloomberg Center 103
| Harvard community only
Organizer: Technology & Operations Management Unit
TOM Seminar: Digital Innovation with High Costs of Entry: Evidence from Software-Driven Medical Devices
Abstract
Does technological opportunity enable the rise of new entrants or reinforce the position of incumbents? Research on this classic topic often ignores the high costs of entry seen in some industries. We offer a novel approach to this question in the context of regulated medical technology, where the introduction of software is of growing importance and has created fresh opportunities for new product development. Pioneering a new application of supervised document classification, we consider over 35,000 new medical devices that came to market in the United States from 2002-2016 in order to identify predictors of digital innovation in this industry. We consider the relative importance of key factors such as geographic and within-firm capabilities and the role of financial resources. We find that location in a region of concentrated expertise and prior firm commercialization experience reinforce one another in predicting digital innovation. While venture capital funding appears to play a role in supporting innovative entrants, closer analysis suggests that this funding selects on other variables that predict digital innovation; in this regulated industry, financial resources do not substitute for existing capabilities. We conclude that incumbent firms have an advantage in innovating in this setting.
April
19, 2018
|
12:30pm -
2:00pm
| Cotting Conference Room
| Faculty and doctoral students only
Organizer: Technology & Operations Management Unit
April
18, 2018
|
4:00pm -
5:20pm
| Baker Library | Bloomberg Center 103
Organizer: Finance Unit, Harvard Economics Department
Seminar
| Finance/Economics Ph.D. Lunch Seminar
Yosub Jung, Harvard University
CEO Leadership and Talent Retention
April
13, 2018
|
12:35pm -
1:10pm
| Baker Library | Bloomberg Center 102
| Open to public
Organizer: Finance Unit, Harvard Economics Department
Seminar
| Finance/Economics Ph.D. Lunch Seminar
Ruiqing Cao, Harvard University
TBD
April
13, 2018
|
12:00pm -
12:35pm
| Baker Library | Bloomberg Center 102
| Open to public
Organizer: Finance Unit, Harvard Economics Department
Seminar
| Science-based Business Seminar
Gokhan Aykac , Gazi Univ Dept of Econ & Harvard Law School
SBBI Seminar: "The Value of an Overseas Research Trip"
This study provides a novel approach to understand and explain the effects of the overseas mobility of the scientists on their scientific productivity as well as on their scientific collaborations and their contributions to diffusion and impact on science. The research also set out to determine how these relations differ between the foreign scientists who have stayed at the USA and who had returned to their home country, as well as investigating the difference that might occur for destination countries other than the USA.
Our comparative case set-up is based on Abadie et al. (2010)’s synthetic control approach that uses data-driven procedures to construct suitable comparison groups. We employed a unique comparison control group design which utilizes immobile scientists’ publication based characteristics to construct a synthetic-author for each mobile scientist. We constructed the author sample from Turkish named authors as Turkey is assigned as the departure country. The methodology of this study can be applied to any departure and destination country.
It has not escaped our attention that our comparative case set-up suggests a remarkable increase in the scientific productivity of the mobile authors. Our results also show that an overseas research trip considerably adds to the contributions to diffusion and impact on science. Findings of the study confirm the notable importance of overseas research trip on scientific productivity of the scientists.
April
13, 2018
|
12:00pm -
1:30pm
| Baker Library | Bloomberg Center 103
| Harvard community only
Organizer: Technology & Operations Management Unit
