Skip to Main Content
HBS Home
  • About
  • Academic Programs
  • Alumni
  • Faculty & Research
  • Baker Library
  • Giving
  • Harvard Business Review
  • Initiatives
  • News
  • Recruit
  • Map / Directions
Faculty & Research
  • Faculty
  • Research
  • Featured Topics
  • Academic Units
  • …→
  • Harvard Business School→
  • Faculty & Research→
Publications
Publications
  • 2024
  • Article
  • Journal of Causal Inference

Neyman Meets Causal Machine Learning: Experimental Evaluation of Individualized Treatment Rules

By: Michael Lingzhi Li and Kosuke Imai
  • Format:Electronic
  • | Pages:19
ShareBar

Abstract

A century ago, Neyman showed how to evaluate the efficacy of treatment using a randomized experiment under a minimal set of assumptions. This classical repeated sampling framework serves as a basis of routine experimental analyses conducted by today’s scientists across disciplines. In this article, we demonstrate that Neyman’s methodology can also be used to experimentally evaluate the efficacy of individualized treatment rules (ITRs), which are derived by modern causal machine learning (ML) algorithms. In particular, we show how to account for additional uncertainty resulting from a training process based on cross-fitting. The primary advantage of Neyman’s approach is that it can be applied to any ITR regardless of the properties of ML algorithms that are used to derive the ITR. We also show, somewhat surprisingly, that for certain metrics, it is more efficient to conduct this ex-post experimental evaluation of an ITR than to conduct an ex-ante experimental evaluation that randomly assigns some units to the ITR. Our analysis demonstrates that Neyman’s repeated sampling framework is as relevant for causal inference today as it has been since its inception.

Keywords

AI and Machine Learning; Research

Citation

Li, Michael Lingzhi, and Kosuke Imai. "Neyman Meets Causal Machine Learning: Experimental Evaluation of Individualized Treatment Rules." Journal of Causal Inference 12, no. 1 (2024).
  • Read Now

About The Author

Michael Lingzhi Li

Technology and Operations Management
→More Publications

More from the Authors

    • 2025
    • Journal of Business & Economic Statistics

    Statistical Inference for Heterogeneous Treatment Effects Discovered by Generic Machine Learning in Randomized Experiments

    By: Kosuke Imai and Michael Lingzhi Li
    • 2024
    • Faculty Research

    Learning to Cover: Online Learning and Optimization with Irreversible Decisions

    By: Alexander Jacquillat and Michael Lingzhi Li
    • July 2024
    • Faculty Research

    Hospital for Special Surgery: Returning to a New Normal? (B)

    By: Robert S. Huckman, Michael Lingzhi Li and Camille Gregory
More from the Authors
  • Statistical Inference for Heterogeneous Treatment Effects Discovered by Generic Machine Learning in Randomized Experiments By: Kosuke Imai and Michael Lingzhi Li
  • Learning to Cover: Online Learning and Optimization with Irreversible Decisions By: Alexander Jacquillat and Michael Lingzhi Li
  • Hospital for Special Surgery: Returning to a New Normal? (B) By: Robert S. Huckman, Michael Lingzhi Li and Camille Gregory
ǁ
Campus Map
Harvard Business School
Soldiers Field
Boston, MA 02163
→Map & Directions
→More Contact Information
  • Make a Gift
  • Site Map
  • Jobs
  • Harvard University
  • Trademarks
  • Policies
  • Accessibility
  • Digital Accessibility
Copyright © President & Fellows of Harvard College.