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Chimeric Antigen Receptor (CAR) T-Cell Therapy: Case Histories of Significant Medical Advances

By: Amar Bhidé and Srikant M. Datar
  • Format:Print
  • | Language:English
  • | Pages:25 
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Abstract

In 2017, the US Food and Drug Administration (FDA) approved an immunotherapeutic treatment, called CAR-T therapy, for two kinds of blood cancers—acute leukemia (ALL) and a lymphoma. We describe 1) how CAR-T works; 2) the foundational advances and discoveries; 3) development of CAR-T therapy; and 4) the situation in 2019.

Keywords

Immunotherapy; Health Care And Treatment; Innovation And Invention; Research And Development; Governing Rules, Regulations, And Reforms

Citation

Bhidé, Amar, and Srikant M. Datar. "Chimeric Antigen Receptor (CAR) T-Cell Therapy: Case Histories of Significant Medical Advances." Harvard Business School Working Paper, No. 21-034, August 2020.

About The Authors

Amar Bhide

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Srikant M. Datar

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