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• Article | JAMA, the Journal of the American Medical Association | September 15, 2020

  Moving the Financing of Graduate Medical Education Into the 21st Century

  Justin A. Grischkan, Ari B. Friedman and Amitabh Chandra

  Citation:

  Grischkan, Justin A., Ari B. Friedman, and Amitabh Chandra. "Moving the Financing of Graduate Medical Education Into the 21st Century." JAMA, the Journal of the American Medical Association 324, no. 11 (September 15, 2020).  View Details

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• Article | NEJM Catalyst Innovations in Care Delivery | September–October 2020

  The Past, Present, and (Near) Future of Gene Therapy and Gene Editing

  Julia Pian, Amitabh Chandra and Ariel Dora Stern

  Emerging gene therapy and gene-editing technologies will have a growing impact on patient lives and health-care delivery. We analyzed a decade of data on clinical trials and venture capital investments to understand the likely trajectory of genetically focused therapies in the years ahead. The number of clinical trials and venture capital deals increased substantially from 2006–2017. We observed particularly notable growth in both industry-sponsored trials and trials involving specialty fields of drug development, including oncology, neurology, hematology, ophthalmology, and neurology. As the number of gene-therapy and gene-editing technologies continues to grow, we expect that such therapies will have a significant and heterogeneous impact on health-care delivery, including a shifting of resources from chronic disease management to more intense acute episodic care, an increase in the complexity of required intellectual property and manufacturing know-how, and the potential expansion of biopharmaceutical companies into service-based business models.

  Keywords: gene therapy; gene editing; Impact; Health Care and Treatment; Technological Innovation; Health Testing and Trials; Venture Capital; Change;

  Citation:

  Pian, Julia, Amitabh Chandra, and Ariel Dora Stern. "The Past, Present, and (Near) Future of Gene Therapy and Gene Editing." NEJM Catalyst Innovations in Care Delivery 1, no. 5 (September–October 2020).  View Details

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• Article | New England Journal of Medicine

  Do We Spend Too Much on Health Care?

  Katherine Baicker and Amitabh Chandra

  Health system reforms—such as changes in insurance design, patient cost sharing, payment reform, or price regulation—should be judged by whether they move us toward higher-value use of resources, rather than by whether they reduce spending.

  Keywords: Health Care and Treatment; Cost; Governing Rules, Regulations, and Reforms; Value Creation;

  Citation:

  Baicker, Katherine, and Amitabh Chandra. "Do We Spend Too Much on Health Care?" New England Journal of Medicine 383, no. 7 (August 13, 2020): 605–608.  View Details

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