It's Time to Reform the Orphan Drug Act

Nicholas  Bagley; Amitabh  Chandra; Craig  Garthwaite; Ariel Dora Stern

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Article | NEJM Catalyst | December 19, 2018

It's Time to Reform the Orphan Drug Act

by Nicholas Bagley, Amitabh Chandra, Craig Garthwaite and Ariel Dora Stern

Format: Electronic

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Citation:

Bagley, Nicholas, Amitabh Chandra, Craig Garthwaite, and Ariel Dora Stern. "It's Time to Reform the Orphan Drug Act." NEJM Catalyst (December 19, 2018).

About the Authors

Amitabh Chandra

Henry and Allison McCance Professor of Business Administration

Technology and Operations Management

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Ariel D. Stern

Poronui Associate Professor of Business Administration

Technology and Operations Management

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Technical Note | HBS Case Collection | November 2019

The Life Sciences Revolution: A Technical Primer

Gary P. Pisano, William J. Anderson, Amitabh Chandra, Clarissa Ceruti and Stephanie Oestreich

For more than two decades, scientific advances have been driving profound changes in drug discovery and the drug industry itself. This case provides an overview and description of these technical and scientific advances. Written for the nonscientific reader, it may be used as companion reading for other case materials that require basic knowledge of the tools, techniques, and approaches used in the pharmaceutical and biotechnology industries.

Keywords: Science; Technological Innovation; Technology; Pharmaceutical Industry; Biotechnology Industry;

Citation:
Pisano, Gary P., William J. Anderson, Amitabh Chandra, Clarissa Ceruti, and Stephanie Oestreich. "The Life Sciences Revolution: A Technical Primer." Harvard Business School Technical Note 620-054, November 2019. View Details

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Article | Annals of the American Academy of Political and Social Science | November 2019

Economic Principles for Medicare Reform

Amitabh Chandra and Craig Garthwaite

In this article, we develop an economic framework for Medicare reform that highlights trade-offs that reform proposals should grapple with, but often ignore. Central to our argument is a tension in administratively set prices, which may improve short-term efficiency but do so at the expense of dynamic efficiency (slowing innovations in new treatments). The smaller the Medicare program is relative to the commercial market, the less important this is; but in a world where there are no market prices or the private sector is very small, the task of setting prices that are dynamically correct becomes more complex. Reforming Medicare should focus on greater incentives to increase competition between Medicare Advantage plans, which necessitates a role for government in ensuring competition; premium support; less use of regulated prices; and less appetite for countless “pay for performance” schemes. We apply this framework to evaluate Medicare for All proposals.

Citation:
Chandra, Amitabh, and Craig Garthwaite. "Economic Principles for Medicare Reform." Annals of the American Academy of Political and Social Science (November 2019): 63 – 92. View Details

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Article | NEJM Catalyst | October 14, 2019

How Artificial Intelligence Is Changing Health Care Delivery

Samantha F. Sanders, Mats Terwiesch, William J. Gordon and Ariel Dora Stern

The development of intelligent machines holds great promise for making health care delivery more accurate, efficient, and accessible, but challenges remain for incorporating AI into clinical and administrative settings.

Keywords: artificial intelligence; Health Care and Treatment; Service Delivery; Technological Innovation;

Citation:
Sanders, Samantha F., Mats Terwiesch, William J. Gordon, and Ariel Dora Stern. "How Artificial Intelligence Is Changing Health Care Delivery." NEJM Catalyst (October 17, 2019). View Details

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It's Time to Reform the Orphan Drug Act

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